You're right about your
GH pulses being most significant during Phase IV sleep, so it's more cost-efficient, at the very least, to NOT shoot near bedtime, which will most likely inhibit the endogenous (free of cherge)
GH pulse during phase IV sleep. Granville also has a theory on other detriments to nightime
GH administration.
GH pulses occur about every 3-5 hours throughout the day, but the magnitude of these pulses are far greater at night. There is no good argument for any X days on/off scheduling other than allowing you to use
GH for longer. However, since the effects are merely additive, all you're doing is delaying the fruits of your
GH usage. The only reason I can think that he's doing 3 on/off is because he's cycling insulin as well. Humalog is a superior insulin due to greater potency per unit time and a shorter total activity period, thus allowing for a shorter period during which an insulin-specific diet must be adhered to....this leads to less potential for fat gain.