"Two mechanisms can account for a lower gland production of the hormone: --a persisting significant rise in the levels of circulating epiniphrine could induce a drop in the plasma levels of
testosterone by means of reduced testicular production, with unchanged global metabolic clearance (32); --- hypercortisolemia, under the condition that it is prolonged enough, would reduce the plasma levels of
testosterone (33,34). This normal profile (hypercortisolemia, hypotestosteronemia) is described in other stress conditions (35,36) and in Cushings's syndrome (37,38,39)..."
So then, could long term use of
clenbuterol, ephedrine, or even caffeine result in hypogonadism? Could the rise in caffeine intake be a culprit in terms of the rising rates of hypogonadism?