[JAF86]

I took Tramadol for a couple of years to combat fatigue and lack of motivation. It worked great and allowed me to workout without feeling a sense of total exhaustion afterwards. The problem was that over the course of the two years I progressively built up a tolerance and had to take larger doses to get the same effect. I'm not sure whether this was due to the opiod-like mechanism of Tramadol or the neuro-transmitter profile. (I believe it boosts both NE and Serotonin levels). I'd like to find a substance that has the same neuro-transmitter profile without the opiod activity in the hopes that I won't develop the tolerance second time around. Any ideas?