Are you on thyroid meds is your thyroid low. I know this is said but I have not seen this happen taking Indolplex/DIM. DIM if you find one that is good a lot of junk out there does not block E2 it converts it into good E's so your liver can wash it out. So even taking some TMG would held do this on DIM.
PhytoPharmica Indolplex with DIM