Fresh blood test results--some telltale abormal values.

[chip douglas]

A month ago I switched primary care provider. As a first step since I was a new patient, she looked over my medical history and labs, and made the decision to run all of those test over to start fresh. So the following blood test are from 3 weeks ago. My chief complaint is with low to non-existant sex drive. Also the units used are Canadian units since test were performed in Canada. However i'll provide U.S. equivalents wherever I can. Note that I'm not on HRT/TRT. I'm not currently taking any hormones or pharmaceutical drugs.


Dihydrotestosterone : 2015 ( [male 20-49 yo] 217 - 1650) PMOL/L

DHEA-S : 11.1 ( 4.0 - 16.3) umol/L

SHBG : not in yet--will post when I get it.


Total Testosterone : 14.8 (8.4 - 28.7) nmol/L

Bioavalable Testosterone : 10.6 ( 2.0 - 14.0) nmol/L

Estradiol-17B : 122 (42 - 151) pmol/L

Cortisol (8 hours) : 623 (160 - 700) nmol/L
Time of draw : 8:30 AM

Cortisol ( 16 hours) : 330 (50 - 500) nmol/L
time of draw 3:30 PM

PSA : 1.1 (0.0 - 1.4) ug/L

TSH : 2.06 Euthyr. 0.27 - 5.0 mUI/L
hypothyr. >5.00
hyperthyr. <0.01


FSH : 3 (2 - 12) U/L

LH : 5 (2 - 9) U/L


Prolactin : 7.2 (4.0 - 15.2) ug/L

Ferritin : 284 (50 - 250) ug/L

Folic acid : 35.8 Normal : (11.9 - 46.7) nmol/L

B12 : 542 Normal : (96 - 568) pmol/L

RBC folate : 1136 (> 634) nmol/L

Homocysteine : 7.6 (3.7 - 13.9) umol/L
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Cholesterol : 4.4 (2.0 - 5.2) mmol/L
Triglycerides : 1.3 (0.5 - 2.0) mmol/L
Cholesterol-HDL : 1.36 (1.00 - 2.60) mmol/L
Cholesterold-LDL : 2.4 ( 2.0 - 3.4) mmol/L
Cholesterol Total/HDL : 3.2 no ref. range provided for this one.
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Urinalysis


Aspect : slightly cloudy
Color : yellow
Volume : 12 mL
Density : 1.025 (1.014 - 1.028)
pH : 5.0 (4.8 - 7.5)
Proteins : Negative Negative g/L
Glucose : Negative Negative mmol/L
Cetonic bodies : Negative Negative mmol/L
Blood : Negative (0 - 5) x10-6 Erc
Leucocytes : Negative Negative x10-6 Lkc
Nitrites : Negative Negative
Urobilinogen : negative Negative umol/L
Bilirubin : Negative Negative umol/L
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Hematology


Leucocytes : 5.1 x10-9/L (4.0 - 12.0)
Erythrocytes : 5.30 x10-12/L (4.40 - 6.00)
Hemoglobin: 160 g/L (140 - 180)
Hematocrit: 0.461 (0.0420 - 0.520)
CGMH: 347 g/L (320 - 365)
VGM : 87 fL (80 - 100)
TGMH: 30.1 pg (27.0 - 34.0)
IDE: 12.0 (10.5 - 16.0)
Platelets: 227.0 x10-9/L (120.0 - 400.0)
VPM: 7.3 fL (7.0 - 10.4)


automated analysis of leucocyte formula :


Relative value Absolute value

Neutrophils : 0.517 2.6 (1.4 - 6.5)
Lymphocytes : 0.340 1.7 (1.2 - 3.4)
Monocytes : 0.101 0.5 (0.1 - 0.8)
Eosinophils: 0.036 0.2 (0.0 - 0.7)
Basophils : 0.006 0.0 (0.0 - 0.2)
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Biochemistry

Glucose 5.0 (4.2 - 6.1) mmol/L
Serum creatinine 70 (62 - 106) umol/L
Sodium 140 (137 - 145) mmol/L
Potassium (plasma) 3.3 (3.4 - 4.8) mmol/L
Chloride 102 (98 - 109) mmol/L
AST 18 (0 - 37) U/L
ALT 19 (0 - 41) U/L
Alkaline Phosphatase 54 (52 - 132) U/L
Total Bilirubin 32 (3 - 22) umol/L
Direct Bilirubin 4 (0 - 7) umol/L
Calcium 2.43 ( 2.15 - 2.65) mmol/L
Uric acid 394 (255 - 430) umol/L
Total protein 79 (63 - 83) g/L
Albumin 51 (35 - 60) g/L
Magnesium 0.97 (0.65 - 1.05) mmol/L
Serum iron 23.4 (9.5 - 29.9) umol/L
Transferrin 2.8 (2.0 - 3.4) g/L
TIBC 64 (47 - 78) umol/L
TRF saturation % 0.37 (0.20 - 0.50)

[chip douglas]

I was worried this evening, and forgot a very important : big thank you to everyone out here for their help. This place feels good as it's all about men helping men.

[hardasnails1973]

Originally Posted by chip douglas

I was worried this evening, and forgot a very important : big thank you to everyone out here for their help. This place feels good as it's all about men helping men.

Alkaline Phosphatase 54 (52 - 132) U/L

Thats low dude and usally indicator or zinc, magnesium or manganese, low progesterone/ cortisol , or elevated estrogen since all of these are bone building nutriients, my normal was 75 all the time and when I first got sick dropped down to 39 but drs ignored it and never has been right ever since..


Total Testosterone : 14.8 (8.4 - 28.7) nmol/L - estrogen can be binding up receptors creating negative feed back to the pituitary to lower LH

Bioavalable Testosterone : 10.6 ( 2.0 - 14.0) nmol/L - not bad, but total test is low

Ferritin : 284 (50 - 250) ug/L - hemochromatosis - could explain alot of your symptoms low testosterone, insulin resistance, impotency, brain fog, emotional content. Donate blood or molybdneum ..increasing testosterone is used to treat it too

estrogen to testosterone SUCKS - could be problems with estrogen metabolism and causing excessive insulin production making you insulin resistance. Dhea may be converting to estrogen vs testosterone due to over active aromatiase or 5 alpha reductase which is driving zinc into the ground. altering your insulin function. Seek RBC or WBC ZINC analysis

Potassium (plasma) 3.3 (3.4 - 4.8) mmol/L - insulin can be driven this into the ground (reflecting insulin ressitance) - seek glucose tolerance test probably show reactive hypoglycemic .. Excess estrogen can make one insulin resistant over time..

Need thyroid ft3 ft4 and make better analyisis

If your free cortisol is low then estrogen/testosterone ratio could be at play because estrogen activates cortisol binding glubulin and causes reduction in free cortisol like shbg does to testosterone.. Lowerint eh estrogen could reduce stress off adrenals and raise testosterone. You need testosterone to uptake zinc into the prostrate to lower the dht and estrogen hmmm .
What optimal for one may be another mans poison for another we all are different. If you had high to begin with and drop say 40% you body may be activing if it is low testosterone despite it being in the normal or optima range...Drs are ignorant to this !!

[hardasnails1973]

Total Bilirubin 32 (3 - 22) umol/L - signs of heavy metabl detoxidfcation or remvoal of toxin in the body. Bile acids may be elevated maywant to check serum bile acids (gliberts syndrome)

[pmgamer18]

You DHT is high but this will not make one feel bad.

SHBG will tell us a lot post this when it comes in.

Your Total T is low to me 427 ng/dl in my units I keep mine at 800 to 1000.

Estradiol in my units is high for me 35.2 pg/ml I keep mine at less then 20 with my SHBG at 22.

Just getting E2 down can bring up Total and Free T levels.

LH and FSH the LH is on and off fast so it's better to go by FSH and this is low normal just by this I would do an MRI on your Pituitary Gland just to be sure you don't have a tumor on it.

Also the low normal Sodium with low Potassium leads me to think pituitay. You need to check your Aldosterone and Renin to see if you have Hypoaldosteronism. Here is a link about it I have this but not real bad.
http://www.stopthethyroidmadness.com...opic.php?t=581
I put a 1/2 tsp of pure Sea Salt into a glass of water first thing in the morning and this makes me feel much better.

Question did you fast on this test first and did you drink at least 2 good glass's of water when you got up for this test. If not this can make things like Ferritin and Hemochromatosis look off because your Dehydrated.

Do test Free T4 and Free T3 your TSH is over 2 this can mean if your feeling bad that thyroid meds may help you to feel better but first get E2 down. Then test.

This is what I see and I am not a Dr. so take this for what it's worth.

[chip douglas]

From Wikipedia on DHT :

Medical conditions which correlate with androgenetic alopecia
Androgenetic alopecia in men has been associated with several other medical conditions including coronary heart disease and enlargement of the prostate. Additionally, prostate cancer, disorders of insulin resistance (such as diabetes and obesity), and high blood pressure (hypertension) have been related to androgenetic alopecia. Notably, the link between androgenetic alopecia and metabolic syndrome is strongest in non-obese men.[1] Medically increasing DHT levels can exacerbate the balding process, but has not been shown to worsen metabolic syndrome indicating that androgen levels are not the link between the two conditions. In women, androgenetic alopecia is associated with an increased risk of polycystic ovary syndrome (PCOS). PCOS is characterized by a hormonal imbalance that can lead to irregular menstruation, acne, excess body hair (hirsutism), and weight gain.
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As soon as SHBG comes in, I'll make sure to post it on here.
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Total T should definately be higher, I fully agree, and pretty much all would too.
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E2 is higher this time than it's ever been on all of the tests I've had for slightly more than year.
DIM as you advised many times, will likely help this. I would have started on it, but was waiting for the test batch to come in.
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My new pcp has talked to me about the possibility of doing an pituitary MRI to rule out any tumor. I guess this is the next step.
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Potassium hangs on the low side, but you find my Sodium to be low too ?

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um, I did a 12 hour fast for all of those tests I posted, as some of them required a 12 hour fast. I can't seem to remember whether I drank couples of glasses of water prior to taking the tests--I'm pretty sure I didn't.
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I'll ask my pcp for FT4/FT3--often my hands are cold, especially my right hand. I'm often cold since I moved into my new place. Something's not right about it. If I recall correctly E2 competes with thyroid for receptor binding, thus can cause low thyroid.


I'm 5'7'' and lost weight (on purpose), and I'm now at 160 lbs--I don't have much fat at all, except abdominal fat (pot belly). High DHT can cause insulin resistance, or at least contribute to it.

Again my chief complaint is low sex drive. Other than anxiety is an issue too, but I do not lack energy most of the time. Anxiety is definately is a pet peeve, no doubt.

For instance, I have been known to have ectopic ventricular beats, which all M.D.'s and internists are not concerned about--they told me they're not actual arrhythmias. But for instance whenever I feel one of those, my anxiety soars and thereafter I keep focusing my mind on the beating of my heart, and this alone makes anxiety much worse.

Thank you so much Phil.

[chip douglas]

I've been suffering with this low sex drive issue for 8+ years now, however I'd had a Mononucleosis diagnosis made 1 and a half year before I was struck with low sex drive. At the time of diagnosis I had no symptoms of mono except for spleen pain that went away fast. Reason was my liver enymes weren't elevated at the time of diagnosis.

I never had any follow up on this with my former primary care provider.

I've wondered about Mycoplasma infection, which if I recall correctly can wreak havoc even once the initial infection is resolved.

[chip douglas]

Further although my blood Cortisol looks fine in the above test samples, not long ago I had urinary Cortisol done and it came in low at :


Urinary Cortisol 87 ( 55--300) nmol/d
duration : 24 hours
Volume : 1 150 mL

[hardasnails1973]

Originally Posted by chip douglas

Further although my blood Cortisol looks fine in the above test samples, not long ago I had urinary Cortisol done and it came in low at :


Urinary Cortisol 87 ( 55--300) nmol/d
duration : 24 hours
Volume : 1 150 mL

Estrogen can bind up free cortisol :P
Not to sound mean or anything since estrogen /test looks out of wack have you ever had the finger up the ass to check prostrate? It could be cutting off ciruclation down there..plus lack of blood flow from low testosterone would not help either.
Hey atleast you got a good looking PCP to do it

check on vitamin D levels (not 1.25 either other one) too chip i bet they are in the shitter !! from being up north and not getting out side much and sunlight is not so intense that can affect your sex drive too !! try some vitamin D at 2000 ius a day for a month then retest levels need to get them in to the upper 80% range to have helath benefit affects

[chip douglas]

Could going to bed late at night for 8 years (that is 1 AM and often later) racking my brains searching the web have brought about the low sex drive ?

Mind you, the low sex drive had already started prior to me getting into this bad lifestyle, and the reason why I'd stay up that late at night for so long, was to find out what was cuasing the low sex drive.

However, this may show a pattern of obsession/compulsion. I've always been obsessive/compulsive about sex, and other stuffs. Obsessions/compulsions can be a major stress, leading to adrenal fatigue I guess.

I'm somewhow ashamed of this behavior.

So to wrap things up, I've always been obsessed over sex/masturbation and watching porn flicks..........sheesh have I sunk low at times

Admitting to this fact is for me quite hard, trust me. I don't know whether I'm admitting something which is common to most men, or if I really went over the limit on this. I recall times where I'd have to do it 7-8 times a day. Of course that is not my daily habit, but i've seen this.

Something I don't understand quite well is despite what seemed to me to be non-existant libido, I still felt the urge to do it all the same. There have been other times where libido was really absent and then I would not touch it at all. That showed me that at times where I thought my sex drive was non-existent, some of it was still there. For years i ran on TCM ying/yang tonics (that was back when i was roughly 24) and my sex drive in those years was unbelievably high--I had to do on the job at times, that should tell you it was high alright

[chip douglas]

Originally Posted by hardasnails1973

Estrogen can bind up free cortisol :P
Not to sound mean or anything since estrogen /test looks out of wack have you ever had the finger up the ass to check prostrate? It could be cutting off ciruclation down there..plus lack of blood flow from low testosterone would not help either.
Hey atleast you got a good looking PCP to do it

check on vitamin D levels (not 1.25 either other one) too chip i bet they are in the shitter !! from being up north and not getting out side much and sunlight is not so intense that can affect your sex drive too !! try some vitamin D at 2000 ius a day for a month then retest levels need to get them in to the upper 80% range to have helath benefit affects

I agree that Vitamin D is likely in the shitter.

A finger up there heh--well, I feel this is going to happen soon--Iike you say, let's look on the bright side ; i got a good-looking lady doc to do it. However this is likely far from pleasant, at least in a medical office setting i mean.