hcg weekly dosesage

[zkt]

Been on T enanthate IM 125mg/week for about 6 weeks now. Althought havent noticed any evidence of testicular atrophy or decreased output ( morning wood is still there) I`m going to start the hcg so as to keep it that way. I`m thinking 750 sub Q weekly. And alternate with T weekly. Whaddyathink ?

[cpeil2]

Originally Posted by zkt

Been on T enanthate IM 125mg/week for about 6 weeks now. Althought havent noticed any evidence of testicular atrophy or decreased output ( morning wood is still there) I`m going to start the hcg so as to keep it that way. I`m thinking 750 sub Q weekly. And alternate with T weekly. Whaddyathink ?

One of the more common ways of using hCG is Dr. Crisler's protocol: 250 IU two days before and the day before your weekly T injection.

[zkt]

I have this thing about needles- the fewer the better.
Hopeing that the smaller gauge will be easier.

[cpeil2]

Originally Posted by zkt

I have this thing about needles- the fewer the better.
Hopeing that the smaller gauge will be easier.

The reconstistuted hCG is of low viscosity so you can use very small guage, e.g. 31g, needle very easily. Sub-q into the belly fat with that fine a needle is essentially painless. Use an slin pin with a short needle.

[zkt]

Guess what the Fed Ex guy just brought ?
What would you expect the shoty term effects of a 750 IU dose to be ?

[cpeil2]

Originally Posted by zkt

Guess what the Fed Ex guy just brought ?
What would you expect the shoty term effects of a 750 IU dose to be ?

Individual response is really variable. Many report "a sense of well-being" within a short period of time (hours). Others don't feel a thing. I used hCG briefly, but I was under a doctor's care who was unfamiliar with the newer ways of using it. I was using 5000 iu once a week as a monotherapy for TRT. At that dose, it was jet fuel.

[KSman]

Research published in May 2005 showed that 250iu SQ EOD restored intratesticular testosterone levels in young normal males where were LH shutdown with 200mg test ester per week.

So 250iu SQ EOD would be a good dose. It keeps the testes working all the time.

Once a week is nuts, the half life will not support it.

Huge doses are dangerous and will down regulate the LH receptor. Disregard all of the posts that you find that suggest large doses. Large does are not better. There is no need to inject IM. What you read stems from product use descriptions targeted at women forcing ovulation.

[cpeil2]

Originally Posted by KSman

Research published in May 2005 showed that 250iu SQ EOD restored intratesticular testosterone levels in young normal males where were LH shutdown with 200mg test ester per week.

So 250iu SQ EOD would be a good dose. It keeps the testes working all the time.

Once a week is nuts, the half life will not support it.

Huge doses are dangerous and will down regulate the LH receptor. Disregard all of the posts that you find that suggest large doses. Large does are not better. There is no need to inject IM. What you read stems from product use descriptions targeted at women forcing ovulation.

No, it wasn't a good alternative. I abandoned it after about a month.

[zkt]

Originally Posted by KSman

Research published in May 2005 showed that 250iu SQ EOD restored intratesticular testosterone levels in young normal males where were LH shutdown with 200mg test ester per week.

So 250iu SQ EOD would be a good dose. It keeps the testes working all the time.

Once a week is nuts, the half life will not support it.

Huge doses are dangerous and will down regulate the LH receptor. Disregard all of the posts that you find that suggest large doses. Large does are not better. There is no need to inject IM. What you read stems from product use descriptions targeted at women forcing ovulation.

Pharmacokinetics
Maximal plasma hCG levels will be reached in males approximately 6 and 16 hours after a single intramuscular or subcutaneous injection of hCG, respectively and in females after approximately 20 hours. HCG is approximately 80 per cent metabolized, predominantly in the kidneys. Intramuscular and subcutaneous administration of hCG were found to be bioequivalent regarding the extent of absorption and the apparent elimination half-lives of approximately 33 hours.

http://home.intekom.com/pharm/donmed/pregnyl.html

You are right. Keep getting it in my head that hcg has a very long half live. Not so.

I have a mild renal impairment to consider and am willing to lose a few Leydig cells in favor of keeping all the renal I have. Twice weekly might be about right for me.

[KSman]

Originally Posted by zkt

[b]Pharmacokinetics


I have a mild renal impairment to consider and am willing to lose a few Leydig cells in favor of keeping all the renal I have. Twice weekly might be about right for me.

If your HPTA was working normally now, that would not stress the kidneys. I would not expect that an equivalent dose of HCG would be a problem.

[zkt]

Yes, assuming that LH and FSH are metabolized in the kidneys and that hcg is equivalent to the pituitary hormones in terms of pound for pound potency.

[JanSz]

Originally Posted by KSman

Research published in May 2005 showed that 250iu SQ EOD restored intratesticular testosterone levels in young normal males where were LH shutdown with 200mg test ester per week.

So 250iu SQ EOD would be a good dose. It keeps the testes working all the time.

Once a week is nuts, the half life will not support it.

Huge doses are dangerous and will down regulate the LH receptor. Disregard all of the posts that you find that suggest large doses. Large does are not better. There is no need to inject IM. What you read stems from product use descriptions targeted at women forcing ovulation.

I am on E3D routine of T + hcg on the same day, two days free.
I like the shots free days.

What would be a proper dose of HCG?
Currently I am using 500iu.
I am 67yo, I think my testis are mostly shot.
On current routine I see some day to day variations in testis firmness, not sure if that would harm me on the long run.
Cosmetical side is acceptable.
I am doing this since 6/19/07
Previously 250iu eod.

Any predictions on how would this hcg routine influence my E, E2 and DHT levels.
Any other angles?

[zkt]

I`d think it would effect DHT and E2 and its metabolites the same as an equivalent T increase would. Hcg IS metabolized in the kidneys and hevent seen anything that leads me to think that hcgs metabolites are bioactive.
Notice any difference on 500 ? How does it make you feel ?

[JanSz]

Originally Posted by zkt

I`d think it would effect DHT and E2 and its metabolites the same as an equivalent T increase would. Hcg IS metabolized in the kidneys and hevent seen anything that leads me to think that hcgs metabolites are bioactive.
Notice any difference on 500 ? How does it make you feel ?

No difference in any feelings or anything.
I was for years on just Androgel my balls were gone.
In Feb/07 I got frendlier doctor and changed to Tcream and HCG.
HCG 250iu EOD
Within 30 days my balls were back to normal size.
My absorbtion of Tcream was low, surprise, because I newer had any absorption problems with Androgel.

[zkt]

A 30g x1/2 in the belly is worse than a 25x1 in the leg. Lotsa nerves in the belly. Not this boy. The 30x1/2 in the thigh isnt too bad.