How is ED caused by adrenal fatigue?

[gettingold]

I can't seem to see the relationship. I don't doubt it exists just don't see it. I know Marianco once said his most difficult ED case was caused by AF. Seems none of the ED drugs helped this particular patient.

[zkt]

Originally Posted by gettingold

I can't seem to see the relationship. I don't doubt it exists just don't see it. I know Marianco once said his most difficult ED case was caused by AF. Seems none of the ED drugs helped this particular patient.

How much do you know of the autonomic system, the HPTA axis, the adrenergic receptor biochemistry, the immune system signaling and a few more areas that dont come to mind?
If you are looking at this from a clinical situation and are feeling daring, doubt if this is the case, shoot it up with testosterone and see what happens. Otherwise more history is needed.
I am investigating adrenal fatigue from an experimental standpoint in dealing with my case of trauma induced arthritus usinf Medrol(methyl prednisolone).
If anyone wants to get into this let me know.
IF your interest is purely theoritical fine- happy to dicsuss it
If persoinal enev better.

[leed]

Originally Posted by zkt

I am investigating adrenal fatigue from an experimental standpoint in dealing with my case of trauma induced arthritus usinf Medrol(methyl prednisolone).
If anyone wants to get into this let me know.
IF your interest is purely theoritical fine- happy to dicsuss it
If persoinal enev better.

Sorry to detract from the OP
Hi ZKT, what 'trauma' was you involved in to begin RA?

When I took 1 month of Isocort last year prior to using Armour thyroid, I noticed my joints less flexible, incredibly noisy and much weaker - i discontinued use after one month but my joints issues and weakness persist (1 year on). Im going to my GP this week to discuss, not certain if its RA at all.

I am a long term beclomethasone (asthma cocortisteroid) user, and wonder if the short spike in Isocort could someohow trigger RA?

[zkt]

Originally Posted by leed

Sorry to detract from the OP
Hi ZKT, what 'trauma' was you involved in to begin RA?

When I took 1 month of Isocort last year prior to using Armour thyroid, I noticed my joints less flexible, incredibly noisy and much weaker - i discontinued use after one month but my joints issues and weakness persist (1 year on). Im going to my GP this week to discuss, not certain if its RA at all.

I am a long term (asthma cocortisteroid) user, and wonder if the short spike in Isocort could someohow trigger RA?

Not RA;OA
I put way too much stress on the left basal and first metacarpal joint. Probable micro fracures of the subchronal bone which led to joint remodeling. Joint remodeling is dependent upon increased local blood flow which can be reduced with glucorticoids and thus stopped.

beclomethasone causes adrenal supression so you may not have enought cortisol to deal with the situations where you need it

[HeadDoc]

Originally Posted by zkt

How much do you know of the autonomic system, the HPTA axis, the adrenergic receptor biochemistry, the immune system signaling and a few more areas that dont come to mind?
If you are looking at this from a clinical situation and are feeling daring, doubt if this is the case, shoot it up with testosterone and see what happens. Otherwise more history is needed.
I am investigating adrenal fatigue from an experimental standpoint in dealing with my case of trauma induced arthritus usinf Medrol(methyl prednisolone).
If anyone wants to get into this let me know.
IF your interest is purely theoritical fine- happy to dicsuss it
If persoinal enev better.

ZKT, please keep us all up on what you find on the topic of arthritis and adrenal fatigue. Are you investigating inbalances at the molecular level, using one of the diagnostic labs? I have some self induced trauma on my left index finger knuckle. The ache only comes out on my pulling day at the gym. Lots of pull-ups, deadlifts, rows, etc. I enjoy lifting heavy. I also had this knuckle injured while moving a feral cat into a cage---the knuckle required around 10-12 stitches around 3-4 years ago. (My wife and I have been feral cat caretakers for many years---we try to socialize the kittens and place them once they have been neutered or spayed. I was moving this particular cat after we concluded that our socialization program was not making progress and we were moving her back to her pride).

[zkt]

Originally Posted by HeadDoc

ZKT, please keep us all up on what you find on the topic of arthritis and adrenal fatigue. Are you investigating inbalances at the molecular level, using one of the diagnostic labs? I have some self induced trauma on my left index finger knuckle. The ache only comes out on my pulling day at the gym. Lots of pull-ups, deadlifts, rows, etc. I enjoy lifting heavy. I also had this knuckle injured while moving a feral cat into a cage---the knuckle required around 10-12 stitches around 3-4 years ago. (My wife and I have been feral cat caretakers for many years---we try to socialize the kittens and place them once they have been neutered or spayed. I was moving this particular cat after we concluded that our socialization program was not making progress and we were moving her back to her pride).

Talked to 3 different docrtors about this and they wouldnt consider methyl prednisolone other than Rxing a 24mg dosepak every 6 months. They werent too interested in ordering labs for me either. So, since paying for a lot of tests out of pocket is not something I want to do- It`s all subjective observations.
Interesting that you had a previous injury at the OA site. So did I and 25 years ago at that. Big dog tried to eat my hand. Many stitches on and around the afflicted joints. The literature says that OA can set in many years after the original injury. I beleive it.
In a nutshell, once subchordral bone, or even tendons or cartlidge, is injured it signals the immune system into local action which increases cirulation in the effected joint. This enables subchrondral bone absorption and redepositation, ie. bone spurs, and subchrondral cysts to delevop mostly around the perifpery of the joint, This reduces mobility and causes pain when you move the joint so as to put pressure on the spur or cyst. I have actually felt these cysts burst with refeif of pain for a while. The increased soft tisue pressure due to inflammation also causes pain. The entire remodeling process is de-[endant upon increased local circulation that conmes with the imflammatory response. Stop the inflammati0nand you stop the pain AND the damage the body is doing in its failing attempt to fix the situation. Thats where the Medrol comes in . IN some cases a wekks treatment might suffice. Didnt for me. I have found it necessary to hold the doseage at a particular level for a few days in order to eliminate Sx. Sout of play it by feel. Then decrease the doseage to zero and baby the hell out of it and try not to give the body the idea that the joint is still injured. Appears to me that there is some kind of memory effect going on here. I contend that given the chance the body will forget about the initiating injury eventually and full painless range of motion will result. I have been playing with this for about 6 months now with various dosing protocols. I had followed the above treatment and was off the medrol and painless then got carried away and hurt it again by overuse. I will take it much easier this time.

[JanSz]

Originally Posted by HeadDoc

ZKT, please keep us all up on what you find on the topic of arthritis and adrenal fatigue. Are you investigating inbalances at the molecular level, using one of the diagnostic labs? I have some self induced trauma on my left index finger knuckle. The ache only comes out on my pulling day at the gym. Lots of pull-ups, deadlifts, rows, etc. I enjoy lifting heavy. I also had this knuckle injured while moving a feral cat into a cage---the knuckle required around 10-12 stitches around 3-4 years ago. (My wife and I have been feral cat caretakers for many years---we try to socialize the kittens and place them once they have been neutered or spayed. I was moving this particular cat after we concluded that our socialization program was not making progress and we were moving her back to her pride).

Hope that you do not mind my off topic on ferral cats.
We have one in our home plus domesticated one.
Couple years ago it came in thru the window while playing with our domesticated cat.
He must have been no more than 2 months old when he came in.
He likes our home, but we newer were able to teach him abut cleanliness.
When we let him outside he keeps clean and there is no problem but if we do not let him out there is a big mess everywhere.
My son lives with us, so usually there is no problem to let himout, but if all three of us live house for couple days we have to lock the poor animal in laundry room and then clean big mess on a way back.

Any advice how to break this habit.
Cat is lovely and the two cats are really good buddies.
----------------------
Thank you for not killing the unsuccesfull cases.

[HeadDoc]

Originally Posted by JanSz

Hope that you do not mind my off topic on ferral cats.
We have one in our home plus domesticated one.
Couple years ago it came in thru the window while playing with our domesticated cat.
He must have been no more than 2 months old when he came in.
He likes our home, but we newer were able to teach him abut cleanliness.
When we let him outside he keeps clean and there is no problem but if we do not let him out there is a big mess everywhere.
My son lives with us, so usually there is no problem to let himout, but if all three of us live house for couple days we have to lock the poor animal in laundry room and then clean big mess on a way back.

Any advice how to break this habit.
Cat is lovely and the two cats are really good buddies.
----------------------
Thank you for not killing the unsuccesfull cases.

Our goal is to humanly treat the ferals for their otherwize attenuated life. The large number of ferals inhabiting our cities is a problem of human creation. Abandon a pet who is not neutered or spayed and the kittens will be feral. Here in Phoenix, pet abandonment is rampant. Given the extended warm weather here, they breed three times a year compared to twice in more temperate climates.

Now to your care of your feral. Ferals are cats living in overdrive. They are hypervigilant and hyperreactive. They are immediately aware of any piece of their environment that is out of place. I am surprised that your cat did not learn to use the litter box early on. We socialize ours by limiting their free access to stimulation and food. We put them our smallest bathroom with some toys, water, and a litter box. We feeds them with out bodies and hands in close proximity. Otherwize they get no food. When they are finished eating, we take the food out of the room. We bring in toys and play with them a few times per day. We touch them often and desensitize them to human touch. Beyond early adolescence, they cannot be socialized.

My best thought on your cat would be to do the socialization program for a few weeks and see how things go. If it fails, make the cat an outdoor cat. Now if the cat is just spraying, he is setting up a territory and doing what he would otherwise do to establish a safe haven for himself. If this is going on, consider making him an outdoor cat. This may be a move to establish dominance over your domesticated cat.

I have often thought that a little prozac would help.

[gettingold]

I am fascinated by the twists and turns a thread can take.

[zkt]

Originally Posted by gettingold

I am fascinated by the twists and turns a thread can take.

LOL

No good deed goes unpunished

Amyltryptiline is often used to calm small animals down

[HeadDoc]

although in terms of fight or flight responding, we are still in the same corner of the universe.

[zkt]

Originally Posted by HeadDoc

although in terms of fight or flight responding, we are still in the same corner of the universe.

When Checkers, the latest addition to the crew, sauntered up to the back door yesterday and pissed on it again, my sympathetic responses hit the roof and just missed the cat.

[cpeil2]

Originally Posted by HeadDoc

I have often thought that a little prozac would help.

Buspar is supposed to be good for cats that spray.

[HeadDoc]

Originally Posted by cpeil2

Buspar is supposed to be good for cats that spray.

interesting. thanks.

[gettingold]

If I were a feral cat could I have ED caused by adrenal fatigue?

[HeadDoc]

Originally Posted by gettingold

If I were a feral cat could I have ED caused by adrenal fatigue?

that and being neutered!