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Old 01-01-2006, 11:07 PM
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Default Injection site for HCG to reduce aromatization

I'm still having symptoms of high E2 (water retention and no morning wood), despite reducing my HCG dosage to 250 IU EOD and taking two Indolplex/DIM ED (one in the am and one in the pm). I inject in the belly (usually about 2 inches up and three inches right or left of the navel using a 30g 5/16" 3/10 cc syringe. I'm wondering if I should try injecting in another site.

Any suggestions?
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Old 01-01-2006, 11:16 PM
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I think that is to close to the belly button but I don't feel it makes any difference. Give it another week and if you don't get some wood you need to do Arimidex.
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Old 01-01-2006, 11:32 PM
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how old are you and do you have a problem with cholesterol,blood sugar,or tryclycerides? i ask because erection problems hoist a red flag for those particular problems. how much testosterone per week are you taking? injectable or gel? are you dieting and doing cardio?
mxim
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Old 01-02-2006, 12:17 AM
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pmgamer18,

I do get wood, just not morning wood and not as strong as I'd like. Unfortunately, with my doc, arimidex is not a possibility. So, until I get a new doc, I have to find other means of controlling E2.

Now, I'm really just tying to find the ideal injection site.

Any thoughts?
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Old 01-02-2006, 04:04 AM
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Quote:
Originally Posted by bassack
I'm still having symptoms of high E2 (water retention and no morning wood), despite reducing my HCG dosage to 250 IU EOD and taking two Indolplex/DIM ED (one in the am and one in the pm). I inject in the belly (usually about 2 inches up and three inches right or left of the navel using a 30g 5/16" 3/10 cc syringe. I'm wondering if I should try injecting in another site.

Any suggestions?
Logically it should not matter where u inject HCG, as it is only a signal to the testie to produce testosterone. This testosterone then converts to E2

Testosterone injections on the other hand "may" vary the amount of E2 created depending on where it is injected - although I have not seen any studies to confirm this.
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Old 01-02-2006, 04:37 AM
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Quote:
Originally Posted by coz
Testosterone injections on the other hand "may" vary the amount of E2 created depending on where it is injected - although I have not seen any studies to confirm this.
So what would your opinion be on where to inject testosterone? I've been shooting it in my ass for more than ten years, and I experienced great aromization. Should I find another area of my body?
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Old 01-02-2006, 08:07 AM
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Quote:
Originally Posted by The_Skeptic
So what would your opinion be on where to inject testosterone? I've been shooting it in my ass for more than ten years, and I experienced great aromization. Should I find another area of my body?
Sorry I honestly have no idea, I would think IM should be simliar no matter where you do it, possibly if their is little fat surounding the muscle it may aromatise less, although it may just be the intial spike in T that causes excessive aromatisation in some... Also unsure about the SubQ method people are experimenting with - will be interesting to see their results
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Old 01-02-2006, 12:06 PM
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If you are doing injections. Perhaps decreasing dose and increasing frequency would help, i.e. instead of 200mg q2weeks, try 100mg q1week or 50mg twice a week.
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Old 01-02-2006, 01:23 PM
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I don't understand what site of hcg injection has to do with Testosterone aromatizing to Estrogen. hCG mimics Luteinizing Hormone which circulates in the blood then gets to the testes and stimulates them to get them to produce T. The testes are nowhere near the abdomen.

WF
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Old 01-02-2006, 01:38 PM
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Quote:
Originally Posted by wildfox
I don't understand what site of hcg injection has to do with Testosterone aromatizing to Estrogen. hCG mimics Luteinizing Hormone which circulates in the blood then gets to the testes and stimulates them to get them to produce T. The testes are nowhere near the abdomen.

WF
I agree 100%.
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Old 01-02-2006, 02:16 PM
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Quote:
Originally Posted by wildfox
I don't understand what site of hcg injection has to do with Testosterone aromatizing to Estrogen. hCG mimics Luteinizing Hormone which circulates in the blood then gets to the testes and stimulates them to get them to produce T. The testes are nowhere near the abdomen.

WF

I was wondering if there is a way, by selecting the injection site, to have the HCG more moderately absorbed and hence reduce any aromatization that arises from a spike. In lieu of that I'm going to try to reduce my dose in half and inject ED instead of EOD and see if that has any effect on my E2 symptoms.
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Old 01-02-2006, 03:31 PM
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Quote:
Originally Posted by bassack
I was wondering if there is a way, by selecting the injection site, to have the HCG more moderately absorbed and hence reduce any aromatization that arises from a spike. In lieu of that I'm going to try to reduce my dose in half and inject ED instead of EOD and see if that has any effect on my E2 symptoms.
I see your point. I think that's why some here recommend taking less hCG more often, as opposed to more hCG less often, which is what you seem to be planning to do.

I know my main issue with aromatization is the fat in my belly, so I'm working that off with exercise.

WF
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Old 01-02-2006, 04:14 PM
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Quote:
Originally Posted by bassack
I was wondering if there is a way, by selecting the injection site, to have the HCG more moderately absorbed and hence reduce any aromatization that arises from a spike. In lieu of that I'm going to try to reduce my dose in half and inject ED instead of EOD and see if that has any effect on my E2 symptoms.
Injecting nightly before bed is working well for me, and seems to (at least in theory) better mimick the bodies natural hormone cycle.
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Old 01-02-2006, 06:11 PM
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Quote:
Originally Posted by bassack
I was wondering if there is a way, by selecting the injection site, to have the HCG more moderately absorbed and hence reduce any aromatization that arises from a spike. In lieu of that I'm going to try to reduce my dose in half and inject ED instead of EOD and see if that has any effect on my E2 symptoms.
David Z is doing HCG only everyday and doing dam good do a search on his post with HCG. I am doing HCG everyday with my shots I see my Dr. tomorrow and am going to break his arm to let me do my shots IM every 3 days .35mls.
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Old 01-03-2006, 06:59 PM
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Quote:
Originally Posted by wildfox
I know my main issue with aromatization is the fat in my belly, so I'm working that off with exercise.

WF
Nice, this is why many men actually can have lower levels the older they get and actually have more aromatase enzyme floating around.
And I thought I was the only guy to hear this


SubQ works fine for me and I dont see how injecting into diffrent fatty areas would have any effect on aromatase.
Amounts would.


Testosterone: Free or Bound?

Testosterone circulates in the blood in two different forms called free and bound.
About 70-80% of circulating testosterone is bound to a protein named sex hormone binding globulin (SHBG)
When testosterone is bound to SHBG it is essentially out of action.
Another 20% or more of circulating testosterone is bound to another protein, albumin.
Testosterone bound to albumin may be biologically available under certain conditions.
This leaves only about 1-3% of circulating testosterone as free, which is completely available and potentially active at testosterone target cells.

Professor Alex Vermeulen found that both total testosterone and free testosterone levels decline with age, while SHBG, which binds testosterone, rendering it permanently unavailable for biological uses, increased. Free testosterone declined farther and faster rate than total testosterone.

Stinging Nettle?
A study in Germany, showed that stinging nettle extract may inhibit the enzyme aromatase.
Other studies have shown that stinging nettle extract binds to the protein SHBG allowing less testosterone to be bound to SHBG allowing for more free testosterone bioavailability.
So if stinging nettle hinders aromatization (actually keeping more testosterone around), and less estradiol floating around (which can reduce LH bad for test production), and bind to SHBG which allows more free testosterone to circulate around in the body. I feel that this for the older guys would help in test production.
Not only that stinging nettle is used in Europe for prostate problems and this is also a older mans disease.

Last edited by hackskii; 01-03-2006 at 07:02 PM.
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