Nolvadex vs. Arimidex.

[pmgamer18]

I read this this morning at the H2 group.
A cut & paste.
To: hypogonadism2@yahoogroups.com
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Date: Sat, 25 Mar 2006 05:39:10 -0000
Subject: [Hypogonadism] Re: Nolvadex vs. Arimidex

Any SERM will block estrogen but will not stop estrogen production, at
some point if you stop
taking the SERM there will be a major flood of blocked estrogen filling
those receptor sites. A
SERM is great if you have any symptoms of gynecomastia, but just
lowering estrogen with
Arimidex will do the same. Arimidex is very very powerful and even .5mg
can drive estrogen
down too low.

--- In hypogonadism2@yahoogroups.com, "Taddeo Tatsulok" <taddeo_t@...>
wrote:
>
> Hi All,
>
> I already know that both medications are used to fight estrogen and
> that Nolvadex is a SERM (Selective Estrogen Receptor Modulator),
while
> Arimidex is an AI (Aromatase Inhibitor). But when would you prefer
> one over the other? Cost aside, what are the instances or conditions
> when you would prefer to use Nolvadex over Arimidex or the latter
over
> the former? Also, how long do you use these medications?
>
> Taddeo
>

[HeadDoc]

thanks for posting this. I really didn't know what to say to Mxim's thread on nova v. clomid.

[The_Skeptic]

So is it not advised to take Arimidex with Nolvadex if you feel the familiar symptoms of high E2 coming on?

[pmgamer18]

Originally Posted by HeadDoc

thanks for posting this. I really didn't know what to say to Mxim's thread on nova v. clomid.

I just hope the men here are not messing with different meds with a Dr.'s suppervision.

[toc67guru]

from swale's recipe for TRT:-

"If a patient has “nipple issues”, even while estrogen is within normal range, I add a SERM, emergently. I prefer Nolvadex over Clomid, and Evista is probably best of all for antagonizing estrogen (although much more expensive). Clomid often induces untoward visual effects (i.e. “tracers”), and can cause emotional lability by virtue of its estrogen agonistic effects at the more peripheral (emotion) brain sites. I do like my patients to keep some Nolvadex on hand, should they experience nipple swelling or sensitivity, so they may begin 40mg per day until the symptoms abate, and then taper to 20 mg QD for a few days, then 10mg for a few more, then finally 5mg QD to taper off.

My TRT male patients who suffer E2 elevations above the top of normal range are placed on 0.25mg of Arimidex every third day. If that is not enough, I use the same dose EOD. It is possible to cut the tiny 1mg tabs into quarters, but here a gel or cream preparation, compounded to convenient dosing, makes a lot of sense. A month later I recheck E2, and make further adjustment if necessary. It is important to not lower estrogen too far, which is easy to do with an AI, as doing so has disastrous effects on the Lipid Profile, bone deposition, etc. I prefer to maintain E in mid-range."


you will see that men can experience nipple issues even when estrogen is in normal range.
a serm like nolvodex is used to quickly compete at the estrogen receptor(nipple) and lower sensitivity and swelling and used on a tapering dose when sensitivity go's away.
an AI is used to keep E2 in check.
however nolvodex is always kept on hand for nipple sensitivity flare ups.

[pmgamer18]

Originally Posted by toc67guru

from swale's recipe for TRT:-

"If a patient has “nipple issues”, even while estrogen is within normal range, I add a SERM, emergently. I prefer Nolvadex over Clomid, and Evista is probably best of all for antagonizing estrogen (although much more expensive). Clomid often induces untoward visual effects (i.e. “tracers”), and can cause emotional lability by virtue of its estrogen agonistic effects at the more peripheral (emotion) brain sites. I do like my patients to keep some Nolvadex on hand, should they experience nipple swelling or sensitivity, so they may begin 40mg per day until the symptoms abate, and then taper to 20 mg QD for a few days, then 10mg for a few more, then finally 5mg QD to taper off.

My TRT male patients who suffer E2 elevations above the top of normal range are placed on 0.25mg of Arimidex every third day. If that is not enough, I use the same dose EOD. It is possible to cut the tiny 1mg tabs into quarters, but here a gel or cream preparation, compounded to convenient dosing, makes a lot of sense. A month later I recheck E2, and make further adjustment if necessary. It is important to not lower estrogen too far, which is easy to do with an AI, as doing so has disastrous effects on the Lipid Profile, bone deposition, etc. I prefer to maintain E in mid-range."


you will see that men can experience nipple issues even when estrogen is in normal range.
a serm like nolvodex is used to quickly compete at the estrogen receptor(nipple) and lower sensitivity and swelling and used on a tapering dose when sensitivity go's away.
an AI is used to keep E2 in check.
however nolvodex is always kept on hand for nipple sensitivity flare ups.

For me Arimidex works and when my nipples act up it means my E2 is up so I just take a higher dose of Arimidex and it is gone. To keep from going to low I use my morning wood as a gauge. I wood stops on a morning I check to see if I can get it up if not I know my E2 went to low. In all time I have been keeping my E2 in check I have never found a dose of Arimidex or for that matter Indolplex/DIM that did not need to be adjusted. There is no constant level of E2 it goes all over the place. To many thing can make it go up or down what we eat or drink. I find it a lot of work to keep in check.

[toc67guru]

phil i had read that the active half life of arimidex was 3 days i didn't think it would have as an immediate effect.

[pmgamer18]

Originally Posted by toc67guru

phil i had read that the active half life of arimidex was 3 days i didn't think it would have as an immediate effect.

A lot of people told me this and one guy did a searc on it and found that taking on a reg. bases works fast. I did not read his search but kept a link in is in here some where.
http://tinyurl.com/9w33q