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Old 12-06-2007, 03:39 AM
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Default TRT not working at all.

Hi guys. I finally got started on TRT two weeks ago. I'm 2 days after my second shot. I'm doing 100mg Test Enanthate Sub-Q. No HCG.

I'm 19 years old and my labs indicate that I have pretty low T, LH,FSH, etc. All well below the norm for my age so my endo started me up on TRT. Along with everything else, my cortisol is a bit low, as is my thyroid, etc. Treatment was tried for that (HC, Armour, etc.) but it did not help much.

So anyway, like I said I'm 2 weeks into my shots and it is REDUCING my libido. My anxiety and depression increased and I'm having trouble maintaing an erection now and my load is reduced to about 75% of what it was.

To be quite honest i NEVER had ANY libido or erection problems, my main problem is major fatigue, brain fog, lack of motivation, lack of facial hair, etc. but libido was always perfect.

I'm started to get a bit panicky and I don't know what to do. Should I just quit while I'm ahead? Am I too young to be on TRT? Should I do more labs? It takes about 1 month before the lab results are available and I don't see my endo until February.

What should I do? How long does T take to stabilize and should I have felt the positive effects by now?
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Old 12-06-2007, 03:48 AM
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Default Re: TRT not working at all.

If the answer is that I need to do more labs and adjust with HCG, SERMS, etc. etc. than I think I will simply drop the T ASAP.

My life was tolerable without the T, even *great* at times, I don't want to mess things up.

Do I need to do some kind of PCT after 2-3 weeks of T if I needed to quit?

What a disappointment this turned out to be..
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Old 12-06-2007, 09:17 AM
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Default Re: TRT not working at all.

Quote:
Originally Posted by noneotherthan View Post
Hi guys. I finally got started on TRT two weeks ago. I'm 2 days after my second shot. I'm doing 100mg Test Enanthate Sub-Q. No HCG.

I'm 19 years old and my labs indicate that I have pretty low T, LH,FSH, etc. All well below the norm for my age so my endo started me up on TRT. Along with everything else, my cortisol is a bit low, as is my thyroid, etc. Treatment was tried for that (HC, Armour, etc.) but it did not help much.

So anyway, like I said I'm 2 weeks into my shots and it is REDUCING my libido. My anxiety and depression increased and I'm having trouble maintaing an erection now and my load is reduced to about 75% of what it was.

To be quite honest i NEVER had ANY libido or erection problems, my main problem is major fatigue, brain fog, lack of motivation, lack of facial hair, etc. but libido was always perfect.

I'm started to get a bit panicky and I don't know what to do. Should I just quit while I'm ahead? Am I too young to be on TRT? Should I do more labs? It takes about 1 month before the lab results are available and I don't see my endo until February.

What should I do? How long does T take to stabilize and should I have felt the positive effects by now?
Give it time and follow what your Dr tells you for now and let everything stabilize
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Old 12-06-2007, 10:37 AM
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Default Re: TRT not working at all.

Yep, I agree. Give your T shots some time. I felt like this too at first, but stabilized after about 4 weeks. Doing pretty well now. Anxiety isn't comfortable, but it's not going to kill you. Tell your doc that you're experiencing a little more anxiety than you'd like and ask him for some Xanax. If you use it CONSERVATIVELY (only during those times when you feel like you're going to jump out of your skin), it will help ease you through until you stabilize. This is what I did - Worked like a charm.
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Old 12-06-2007, 11:05 AM
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Default Re: TRT not working at all.

From what you saying about your tests your Seconday and could have a pituitary tumor but did you have your Estradiol tested with this lab. Seeing and Endo I would think no. Your problem may well be you don't have low t and your estradiol is to high. Most men when testing this that have low T with low LH and FSH need to test there Estradiol if this is high the brain thinks your high Estradiol is Testostereone and stops sending the messages of LH and FSH to your testis to make testosteron.

If you had your Estradiol tested with these labs before going on TRT and they were OK then you need to get an MRI on your Pituitary to rule out a tumor. And you need to go back on treating your low cortisol and Thyroid levels. And test other things the pituitary dose and find what is low and treat it.

I know this because I have Hypopituitary do to a head injury and it took me 23 yrs to figure this out. Now I treat every thing that is low and after all these yrs. I am now doing better. If you need more info you can find me here or at this site.
Real Thyroid Help Forums :: View Forum - For Men Only!
Quote:
Originally Posted by noneotherthan View Post
Hi guys. I finally got started on TRT two weeks ago. I'm 2 days after my second shot. I'm doing 100mg Test Enanthate Sub-Q. No HCG.

I'm 19 years old and my labs indicate that I have pretty low T, LH,FSH, etc. All well below the norm for my age so my endo started me up on TRT. Along with everything else, my cortisol is a bit low, as is my thyroid, etc. Treatment was tried for that (HC, Armour, etc.) but it did not help much.

So anyway, like I said I'm 2 weeks into my shots and it is REDUCING my libido. My anxiety and depression increased and I'm having trouble maintaing an erection now and my load is reduced to about 75% of what it was.

To be quite honest i NEVER had ANY libido or erection problems, my main problem is major fatigue, brain fog, lack of motivation, lack of facial hair, etc. but libido was always perfect.

I'm started to get a bit panicky and I don't know what to do. Should I just quit while I'm ahead? Am I too young to be on TRT? Should I do more labs? It takes about 1 month before the lab results are available and I don't see my endo until February.

What should I do? How long does T take to stabilize and should I have felt the positive effects by now?
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Old 12-06-2007, 11:43 AM
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Default Re: TRT not working at all.

Phil is right. I didn't think about it from the E2 angle (i.e., that your anxiety could be related to T converting to E2). I am "lucky" (in a way), because my E2 has always been low. So T shots have barely raised my E2 levels. Even still, I would hang in there, if you can, keep doing the shots and see what the next blood test reveals.
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Old 12-06-2007, 12:33 PM
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Default Re: TRT not working at all.

I had bad panic attacks with high E2 levels. If his E2 was high when he started yes the T shots are makeing worse. He needs to get back to us.
Quote:
Originally Posted by MacDonnell View Post
Phil is right. I didn't think about it from the E2 angle (i.e., that your anxiety could be related to T converting to E2). I am "lucky" (in a way), because my E2 has always been low. So T shots have barely raised my E2 levels. Even still, I would hang in there, if you can, keep doing the shots and see what the next blood test reveals.
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Old 12-06-2007, 12:41 PM
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Default Re: TRT not working at all.

Estradiol isn't high.

Anxiety isn't bad enough to warrant Xanax (I already have some anyway), I'm just stumped that Im not feeling any better at all after the 2nd week.

MRI was done and nothing was found either.

FSH: 2.1 U/L 1.4 - 18.1

LH: 3 UI/L 1.5 - 9.3

Test: 11.95 nmol/L 10 - 30

Bioavailable test: 6.4 nmol/L 3.5 - 18.8

estradiol: 80 pmol/L 55 - 198

cortisol AM: 456 nmol/L 165 - 850

TSH: 1.61 mU/L 0.27 - 4.2

01/06/07 blood test results:

TOTAL TESTOSTERONE: 6,8 10,0-30,0 nmol/L

SHBG: 13 12-46

FREE TEST: 218,0 223,0 - 915,0

BIOAVAILABLE TEST: 4,5 4,6-18,8

SALIVA:

Free cortisols:

AM: 13 Normal: 13-24 nM
NOON: 6 Normal: 5-10 nM
AFTERNOON: 4 Normal: 3-8 nM
MIDNIGHT: 1 Normal: 1-4 nM

DHEA: 7 Normal: 3-10 ng/ml
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Old 12-06-2007, 01:09 PM
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Default Re: TRT not working at all.

noneotherthan, i can relate fully to what you are saying. I am 24 year's old (25 in a few months) and developed low testosterone symptoms, hypothyroidism and adrenal issues thanks to varicocele (testicular vein swelling).

Technically i am primary, but i don't have elevated LH or FSH. Much like you i was left in a kind of limber with low levels. Except my thyroid ended up worse than your's and i had bad ED/no libido.

I assume the blood work you posted was BEFORE testosterone injections (and other medications) were started?

Testosterone can down regulate/slow down your thyroid funtion, which is why you felt bad and me too when i did TRT.

When i went on weekly injections i ended up with worse libido and ED than before (the same as yourself). It wasn't fun to say the least, so i quickly came back off again.

I believe in our situation's we need to treat everything at one time. Adrenals, thyroid and sex hormones (more so if you are secondary).

You're thyroid is low (judging by tsh - which isn't accurate anyway), get a full check up done (free t3/t4 + reverse t3).
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Old 12-06-2007, 01:29 PM
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Default Re: TRT not working at all.

For your FSH and LH to be this low with your testosterone at 344 in US units. I believe your seconday. Have ever had head injury been Knocked out. This will do it.

Your Estradiol is 21pg/ml and this is dam good.

Your morning cortisol is 16ug/dl this labs lowered this range your low 25 would be good about avg.

Your slaiva is very low for am and across the board.
Looks like stage 4 or 5 to me.

How long did you try treating your Cortisol and Thyroid and what did you use.
I have been at treating this for a yr. now just found out my Ferritin levels were below normal and started on Iron now I feel this kicked in my Thyroid meds to work I lose 10.5 lbs last week and feel dam good now.

As for your shots of T you need to give it more time you need to get your levels up into the upper 1/3 of your labs range for TT and FT and keep checking your E2. Try to keep it where you are now. As your levels come up your body will start to undo the damage done by the low T and you will start to feel better is slow for most and takes time. Your lucky on your libido your young and your E2 is good.

I would look into going back on treating your Cortisol levels and Thyroid.
Here is a link on how I got started.
Real Thyroid Help Forums :: View topic - How I got started treating my Adrenals and Thyroid.

If I were you I would keep all my bases covered just look at what low Iron did to me.
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Old 12-06-2007, 02:34 PM
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Default Re: TRT not working at all.

Quote:
Originally Posted by pmgamer18 View Post
For your FSH and LH to be this low with your testosterone at 344 in US units. I believe your seconday. Have ever had head injury been Knocked out. This will do it.

Your Estradiol is 21pg/ml and this is dam good.

Your morning cortisol is 16ug/dl this labs lowered this range your low 25 would be good about avg.

Your slaiva is very low for am and across the board.
Looks like stage 4 or 5 to me.

How long did you try treating your Cortisol and Thyroid and what did you use.
I have been at treating this for a yr. now just found out my Ferritin levels were below normal and started on Iron now I feel this kicked in my Thyroid meds to work I lose 10.5 lbs last week and feel dam good now.

As for your shots of T you need to give it more time you need to get your levels up into the upper 1/3 of your labs range for TT and FT and keep checking your E2. Try to keep it where you are now. As your levels come up your body will start to undo the damage done by the low T and you will start to feel better is slow for most and takes time. Your lucky on your libido your young and your E2 is good.

I would look into going back on treating your Cortisol levels and Thyroid.
Here is a link on how I got started.
Real Thyroid Help Forums :: View topic - How I got started treating my Adrenals and Thyroid.

If I were you I would keep all my bases covered just look at what low Iron did to me.
where did you get those labs at

That is the wrong estradiol test
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Old 12-06-2007, 02:35 PM
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Default Re: TRT not working at all.

Quote:
Originally Posted by noneotherthan View Post
Hi guys. I finally got started on TRT two weeks ago. I'm 2 days after my second shot. I'm doing 100mg Test Enanthate Sub-Q. No HCG.

I
I don't like the idea of injecting 100mg T Sub Q once per week.
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Old 12-06-2007, 02:55 PM
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Default Re: TRT not working at all.

Your right PC I ment to say something on this but missed the boat. He is doing a dam big shot subQ and it would be better if he tried shooting into his thigh or do his shots 2x 's a week of evrey 3 days like Dr. Shippen does.
Quote:
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I don't like the idea of injecting 100mg T Sub Q once per week.
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Old 12-06-2007, 04:34 PM
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Default Re: TRT not working at all.

Quote:
Originally Posted by pmgamer18 View Post
Your right PC I ment to say something on this but missed the boat. He is doing a dam big shot subQ and it would be better if he tried shooting into his thigh or do his shots 2x 's a week of evrey 3 days like Dr. Shippen does.
I would imagine that a Sub Q inject of a whopping 100 mgs would have an extremely slow release time, thus leaving alot of that T around in the belly fat to convert to estrogen

Either way, these esters aren't designed to be injected Sub Q in the first place - Many are simply experimenting. With small frequent doses, I can see where it would benefit.

But a once a week sub Q dose? First I have ever heard of. I think some of these Dr's are just simply having fun and playing guinea pig with a lot of you.
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Old 12-06-2007, 04:56 PM
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Default Re: TRT not working at all.

Quote:
Originally Posted by plymouth city View Post
But a once a week sub Q dose? First I have ever heard of. I think some of these Dr's are just simply having fun and playing guinea pig with a lot of you.

PC before I changed Dr's I was a 1 a week 100mg sub Q dose patient.
Now eod .30cc IM 200mg/ml Testosterone Cypionate
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