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Men's Health Forum: This is a discussion on 3 1/2 day dosing of Testosterone cypionate within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; Has anyone tried this (e.g., injections on Sunday morning and Wednesday night each week)? Mranak, I noticed that you were ...


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Old 09-17-2005, 04:22 AM
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Default 3 1/2 day dosing of Testosterone cypionate

Has anyone tried this (e.g., injections on Sunday morning and Wednesday night each week)? Mranak, I noticed that you were contemplating this idea on another forum earlier this year as you waited for your doctor to prescribe HCG . . . did you ever try it?
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Old 09-17-2005, 12:35 PM
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I tried 100 mgs. of depo T shots every 5 days and it did not bring my levels up much. I still felt a drop in how I felt after the 4th to 5 th day. But upping my shot to 150 mgs. every 7 days I felt much better. Doing what you are taking about will build up in time because of he Half Life of the shot. Plus I did not like getting that shot every 5 days. It is hard enough as it is to do one every 7 days.
Phil
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Old 09-17-2005, 06:48 PM
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Hi Phil,

Someone please correct me if I'm wrong about any of this, but my understanding is that once you've reached the steady state on a particular dosage level, it will no longer accumulate, even if the half-life is longer than 3 1/2 days. On the other hand, given the same total weekly dosage (e.g., 50mg every 3 1/2 days versus 100mg every 7 days), I'm wondering if the steady state levels (the troughs and peaks) would end up higher overall using the shorter dosing interval. So what this might mean (if true) is that if you dosed every 3 1/2 days then you might only need to do a total of 70mg T-cyp (i.e., 2x35mg) per week to put you into the same theraputic range that 100mg every 7 days gives you - with the additional benefit that the distances between the troughs and peaks are smaller, i.e., you have a steadier steady state (no pun intended). I've attached a diagram (I hope) which might be helpful that shows a hypothetical drug being dosed at time intervals of (1) 0.5 x half-life, (2) half-life, (3) 2 x half-life.

It sounds good in theory anyway - except for the extra injections part. Are you giving the injections to yourself? My first injection (gluteal) was given by a nurse who (a) didn't replace the needle with a fresh one after piercing the septum of the T-cyp vial, and who (b) depressed the plunger too quickly to inject the oil, and it hurt a good deal for days afterwards. When a different nurse performed the operation correctly, there was zero pain. Both used a 22 gauge, 1 1/2" needle. I'm doing them myself now using a 25 gauge 1" needle (thighs) and I haven't gotten as good as the second nurse, but I'm way the heck better than the first. I'm going to try my first gluteal self-injection tomorrow . . .

Frank
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File Type: gif Steady state results at different dosing intervals.gif (12.2 KB, 20 views)

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Old 09-17-2005, 07:12 PM
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Frank I feel you are right here but for me I did not get much out of it because the dose was to low to start. I don't give my self shots all the time only when I can't get to my Dr. office. I have got good at it but don't like the way it feels in my leg. I end up with a sore spot for 3 to 4 days doing 150 mgs. is a lot to me for the leg.
Phil
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Old 09-17-2005, 07:53 PM
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Quote:
Originally Posted by frankwhardy
Has anyone tried this (e.g., injections on Sunday morning and Wednesday night each week)? Mranak, I noticed that you were contemplating this idea on another forum earlier this year as you waited for your doctor to prescribe HCG . . . did you ever try it?
In fact, I have done biw (twice weekly) injections as of recently. And my very subjective opinion is that I feel better.

If I were to receive an injection every day of the week; some of them placebo and some of them real testosterone, I think that I could do a decent job at judging which injections were real and which were not.

...but I unfortuantely can't say the same for my hCG injections. That isn't to say that the hCG doesn't help, it is only to say that I don't readily notice the effects.
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Old 09-18-2005, 01:52 PM
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Quote:
Originally Posted by mranak
In fact, I have done biw (twice weekly) injections as of recently. And my very subjective opinion is that I feel better.

If I were to receive an injection every day of the week; some of them placebo and some of them real testosterone, I think that I could do a decent job at judging which injections were real and which were not.

...but I unfortuantely can't say the same for my hCG injections. That isn't to say that the hCG doesn't help, it is only to say that I don't readily notice the effects.
mranak did you ever feel the feeling of well being from any HCG shot. And do you know if your levels went up on the HCG.
Phil
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Old 09-18-2005, 04:37 PM
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Quote:
Originally Posted by pmgamer18
mranak did you ever feel the feeling of well being from any HCG shot.
Nope.
Quote:
Originally Posted by pmgamer18
And do you know if your levels went up on the HCG.
I honestly don't know. My tests thus far have already been the day before usage of hCG.

I am using the APP brand, so maybe that is why. However, I myself am not going to make any conclusions unless I am able to try one of the other brands first. My physician is a bit shakey on the hCG thing, however, so I need to be careful is trying to get a name-brand prescription. I don't want him to suddenly decide that I don't need the hCG.
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Old 09-18-2005, 05:26 PM
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I have 5 box's of he APP brand and MedcoHealth told me they had a lot of men calling them that it does not work. They us to make the Novarel I first started out on and it lasted 60 days. I under stand that both APP and Novarel are a generic. I can't say how you can get your Dr. over to giving you Pregnyl or Profasi. But you could try and telling him you talked to other men on the boards that are having a porblem with the Generic brands. MedcoHealth told me that most scripts the get the box is checked for no Generic on HCG. But that is just one person that works for them saying this.
Phil
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Old 09-18-2005, 06:02 PM
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Quote:
Originally Posted by frankwhardy
My first injection (gluteal) was given by a nurse who (a) didn't replace the needle with a fresh one after piercing the septum of the T-cyp vial, and who
are you supposed to replace the needle after piercing the vial?

i was never told to do this...
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Old 09-18-2005, 07:44 PM
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Quote:
Originally Posted by frankwhardy
Someone please correct me if I'm wrong about any of this, but my understanding is that once you've reached the steady state on a particular dosage level, it will no longer accumulate, even if the half-life is longer than 3 1/2 days.
Doing 1/2 the injection of T. Cyp. every 3.5 days instead of the entire amount every 7 days will not cause an ever increasing build up of T. You will reach a more or less steady state, but there really doesn't seem to be a clear idea of just what a graph of your levels would look like. It may be worse than if you did it weekly, the same or better. Too many variables to just intuit an answer.
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Old 09-18-2005, 07:47 PM
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Quote:
Originally Posted by LiquidGib
are you supposed to replace the needle after piercing the vial?

i was never told to do this...
Some seem to feel that piercing the vial dulls the needle enough to make an injection with the same needle more painful. Some don't.

I've tried both and I didn't notice a difference. Now I stick to the same needle, it's cheaper and I eliminate a potential source of contamination.
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Old 09-18-2005, 08:41 PM
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I learned the hard way, don't put the same needle in the vial a second time. OUCH!

Chris
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Old 09-18-2005, 11:07 PM
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Quote:
Originally Posted by pmgamer18
I have 5 box's of he APP brand and MedcoHealth told me they had a lot of men calling them that it does not work. They us to make the Novarel I first started out on and it lasted 60 days. I under stand that both APP and Novarel are a generic. I can't say how you can get your Dr. over to giving you Pregnyl or Profasi. But you could try and telling him you talked to other men on the boards that are having a porblem with the Generic brands. MedcoHealth told me that most scripts the get the box is checked for no Generic on HCG. But that is just one person that works for them saying this.
Phil
Hopefully I can get the Profasi or the Pregnyl and then I can give a report and we'll have some more data.
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Old 09-18-2005, 11:10 PM
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Quote:
Originally Posted by caos
Doing 1/2 the injection of T. Cyp. every 3.5 days instead of the entire amount every 7 days will not cause an ever increasing build up of T. You will reach a more or less steady state, but there really doesn't seem to be a clear idea of just what a graph of your levels would look like. It may be worse than if you did it weekly, the same or better. Too many variables to just intuit an answer.
Surely, more frequent dosing (with dosage amount adjusted appropriately) will provide more stable serum testosterone levels. Many leading-edge guys in the AAS world have already figured this out and go their injections of test cyp or test enan twice/week.
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Old 09-18-2005, 11:41 PM
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Quote:
Originally Posted by mranak
In fact, I have done biw (twice weekly) injections as of recently. And my very subjective opinion is that I feel better.
Hi Mranak,

Did you try a shorter frequency, like every 5 days (E5D), before trying twice weekly (E3.5D)? If so, I was just wondering if you see a clear trend, with every E5D better than E7D, and E3.5D better than E5D? If you don't mind me asking, I was wondering what your dosage is, too?

So far, for me, E5D is noticably better than E7D - things are more level (energywise), but unless there is further improvement in raising the overall level, the amount I'm injecting (70mg E5D = approx. 100mg/wk) will definitely need to be upped. With the E5D seemingly giving a relatively steady level (so far), I think I'll try upping the dosage in a few weeks, perhaps to 80mg E5D (= approx. 110mg/wk), before I go to E3.5D. At E3.5D, I may need to find a fifth and sixth location (e.g., deltoids, in addition to quads and glutes) to inject to avoid excessive needle trauma. Really, the only bad thing about E5D, for me, is having to do it on a different day each time.
Frank
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