Adrenal Thread

[s0b]

More blood tests, more insight yet more confusion as to what i must do.

So now all comes in handy and is well explanatory but i would like your opinion as well, as i m getting more confused about treatment.

I think i found the reason behing my depleted Cortisol Output after noon

This is my cortisol curve, once again

8am cortisol ----> 20 nM <--- (normal is 13-24)
12am cortisol ----> 5 nM <--- (normal is 5-10nM) - thus im on the lower margin at noon time
4pm cortisol -----> 1 nM <---- (normal is 3-8) - Depressed output
12midnight ------> 1 nM <----- (normal 1-4) - Normal



Insulin Fasting <3 Normal is 3-12 IU/ml
Insulin Postprandial <3 normal is 5-20 IU/ml (depressed)

Dhea 5 ng/ml (3-10)

And now i look at my norepinephrine values

375 pg/ml (normal is 120-350) and that measurement was while i was lying down in bed

I didnt have a testing while standing up as i was supposed to because doctors simply didnt think it was important !!! most of my problems come about when i stand up though

Furthermore i look at free testosterone levels.
My latest results are 16.50 pg/ml (8.7-54) is normal range
This is the lowest free testo levels i have been having in all my life.
Last yr i was also in same shit, overtrained the lowest it went down to was 17.5.

LH is around 4.5 (1.7-10) is considered normal
FsH is around 2.3 (1.7-12) is normal values

And now im thinking, 2 days from now im ready to start on cortef.
I was told to take 5mg of cortef at noon time.

But my goal is to bring down my high norepinephrine levels, limit this sympathetic overcharge, and thus decrease the amount of stress in my body and get back to the anabolic state i used to be.

My testo is low my while my cortisol is also low. What should i do? Try to increase cortisol or increase testosterone? Or both? If i increase cortisol, maybe i feel less stressed but wont this cause a more catabolic state? I initially got into overtraining due to drop in free testosterone (it was down to 8.5 eight months ago) and high rise in cortisol.

Anyone last advice before i jump into making some serious mistake.
Is testosterone or cortisol better for holding back and bringing down norepinephrine?

Last few days i managed to go running. I thought some minor exercise might bring some small ups in my resting testosterone levels.
I run about 500-600 meters and shot some hoops. I didnt sweat at all, my quads/biceps hurt a bit, but i didnt have dyspnea or bronchitis and that was good, yet i didnt really feel good afterwards. My temperature was still very low despite doing at least 20 minutes of running around. The only reason i thing i should take cortisol is to help my thyroid and my metabolism but i have been reading that testosterone can do that as well.

Last but not least TRT or HcG? My doctor said i should test again for FSH,LH and all androgens.

Maybe i should get some dopamine/serotonin urine testing as well.

I would also like you to suggest some books if you know about testosterone and gonadotropins and replacement therapies. I looked into google and found tons but dont know whats the must

[JanSz]

Originally Posted by s0b

More blood tests, more insight yet more confusion as to what i must do.

So now all comes in handy and is well explanatory but i would like your opinion as well, as i m getting more confused about treatment.

I think i found the reason behing my depleted Cortisol Output after noon

This is my cortisol curve, once again

8am cortisol ----> 20 nM <--- (normal is 13-24)
12am cortisol ----> 5 nM <--- (normal is 5-10nM) - thus im on the lower margin at noon time
4pm cortisol -----> 1 nM <---- (normal is 3-8) - Depressed output
12midnight ------> 1 nM <----- (normal 1-4) - Normal



Insulin Fasting <3 Normal is 3-12 IU/ml
Insulin Postprandial <3 normal is 5-20 IU/ml (depressed)

Dhea 5 ng/ml (3-10)

And now i look at my norepinephrine values

375 pg/ml (normal is 120-350) and that measurement was while i was lying down in bed

I didnt have a testing while standing up as i was supposed to because doctors simply didnt think it was important !!! most of my problems come about when i stand up though

Furthermore i look at free testosterone levels.
My latest results are 16.50 pg/ml (8.7-54) is normal range
This is the lowest free testo levels i have been having in all my life.
Last yr i was also in same shit, overtrained the lowest it went down to was 17.5.

LH is around 4.5 (1.7-10) is considered normal
FsH is around 2.3 (1.7-12) is normal values

And now im thinking, 2 days from now im ready to start on cortef.
I was told to take 5mg of cortef at noon time.

But my goal is to bring down my high norepinephrine levels, limit this sympathetic overcharge, and thus decrease the amount of stress in my body and get back to the anabolic state i used to be.

My testo is low my while my cortisol is also low. What should i do? Try to increase cortisol or increase testosterone? Or both? If i increase cortisol, maybe i feel less stressed but wont this cause a more catabolic state? I initially got into overtraining due to drop in free testosterone (it was down to 8.5 eight months ago) and high rise in cortisol.

Anyone last advice before i jump into making some serious mistake.
Is testosterone or cortisol better for holding back and bringing down norepinephrine?

Last few days i managed to go running. I thought some minor exercise might bring some small ups in my resting testosterone levels.
I run about 500-600 meters and shot some hoops. I didnt sweat at all, my quads/biceps hurt a bit, but i didnt have dyspnea or bronchitis and that was good, yet i didnt really feel good afterwards. My temperature was still very low despite doing at least 20 minutes of running around. The only reason i thing i should take cortisol is to help my thyroid and my metabolism but i have been reading that testosterone can do that as well.

Last but not least TRT or HcG? My doctor said i should test again for FSH,LH and all androgens.

Maybe i should get some dopamine/serotonin urine testing as well.

I would also like you to suggest some books if you know about testosterone and gonadotropins and replacement therapies. I looked into google and found tons but dont know whats the must

Read page 6 of my test.
Start with
Neurotransmitters metabolites.

Possibly test like that would be helpfull to you.
JanSz-Metabolic Analysis and Cellular Energy

Attachment #8 on that test have suggested corrective actions, names of supplements, suggested doses.
They do not sell supplements, you have to get them elsewhere.

Link to where to get that test in in post #44
Jan's BloodTest April13/2007 - Page 2

[pmgamer18]

Here is what I feel you need to do this is way over our heads and one guy I know that is dam good at this helped me a lot is Chris. Go to this link and post this to him see what he says tell him Phil sent you.
Real Thyroid Help Forums :: View Forum - Hypopituitary

Originally Posted by s0b

More blood tests, more insight yet more confusion as to what i must do.

So now all comes in handy and is well explanatory but i would like your opinion as well, as i m getting more confused about treatment.

I think i found the reason behing my depleted Cortisol Output after noon

This is my cortisol curve, once again

8am cortisol ----> 20 nM <--- (normal is 13-24)
12am cortisol ----> 5 nM <--- (normal is 5-10nM) - thus im on the lower margin at noon time
4pm cortisol -----> 1 nM <---- (normal is 3-8) - Depressed output
12midnight ------> 1 nM <----- (normal 1-4) - Normal



Insulin Fasting <3 Normal is 3-12 IU/ml
Insulin Postprandial <3 normal is 5-20 IU/ml (depressed)

Dhea 5 ng/ml (3-10)

And now i look at my norepinephrine values

375 pg/ml (normal is 120-350) and that measurement was while i was lying down in bed

I didnt have a testing while standing up as i was supposed to because doctors simply didnt think it was important !!! most of my problems come about when i stand up though

Furthermore i look at free testosterone levels.
My latest results are 16.50 pg/ml (8.7-54) is normal range
This is the lowest free testo levels i have been having in all my life.
Last yr i was also in same shit, overtrained the lowest it went down to was 17.5.

LH is around 4.5 (1.7-10) is considered normal
FsH is around 2.3 (1.7-12) is normal values

And now im thinking, 2 days from now im ready to start on cortef.
I was told to take 5mg of cortef at noon time.

But my goal is to bring down my high norepinephrine levels, limit this sympathetic overcharge, and thus decrease the amount of stress in my body and get back to the anabolic state i used to be.

My testo is low my while my cortisol is also low. What should i do? Try to increase cortisol or increase testosterone? Or both? If i increase cortisol, maybe i feel less stressed but wont this cause a more catabolic state? I initially got into overtraining due to drop in free testosterone (it was down to 8.5 eight months ago) and high rise in cortisol.

Anyone last advice before i jump into making some serious mistake.
Is testosterone or cortisol better for holding back and bringing down norepinephrine?

Last few days i managed to go running. I thought some minor exercise might bring some small ups in my resting testosterone levels.
I run about 500-600 meters and shot some hoops. I didnt sweat at all, my quads/biceps hurt a bit, but i didnt have dyspnea or bronchitis and that was good, yet i didnt really feel good afterwards. My temperature was still very low despite doing at least 20 minutes of running around. The only reason i thing i should take cortisol is to help my thyroid and my metabolism but i have been reading that testosterone can do that as well.

Last but not least TRT or HcG? My doctor said i should test again for FSH,LH and all androgens.

Maybe i should get some dopamine/serotonin urine testing as well.

I would also like you to suggest some books if you know about testosterone and gonadotropins and replacement therapies. I looked into google and found tons but dont know whats the must

[marsaday]

hi

i have been referred to this thread by the yahoo hypogonadism forum because there is relevant info here. i was hoping i could get some feedback from some members. this is my story.

i am 36 and we are trying for a baby and no joy so i have been tested and have low fertility. Light bulb goes off ! i have a referral mid may with the urologist.

since the age of 21 i have had non stop depression. i have always said to the docs i think i have a problem with testosterone and asked for blood tests. they are always normal. my life is great, so i cannot understand why i have depression. i am 13st of lean muscle, and very active, don't smoke or do drugs and drink maybe 3 beers a week. i already do the things people should do when they have depression.

i have some basic symptoms which never seem to change. they can be more severe on a day to day basis. at the moment it is one day good and one day bad etc.

what happens is like someone switching on a light. my body either comes to life or stops working.

this is what happens:

energy stops - tired, head in a fog, poor concentration
appetite goes
muscles decrease in size slightly - not as chunky
don't need to drink as much water
stamina drops off
not as strong
skin becomes drier
breathing tightens up (cant get a nice big breath full)
sexual desire decreases

i take one tablet of the AD effexor per day and carbomazapine (used to treat epilepsy commonly
nightly as a mood stabilizer. i have tried many timed to come off these things but no joy. my symptoms come back stronger and last almost permanently if i do.

one other thing, i had an undescended testicle and had it operated on when i was 9.

my thinking is i have primary late onset hypogonadism - low testosterone.

any help will be appreciated.
i am in the uk by the way.

[JanSz]

Originally Posted by marsaday

hi

i have been referred to this thread by the yahoo hypogonadism forum because there is relevant info here. i was hoping i could get some feedback from some members. this is my story.

i am 36 and we are trying for a baby and no joy so i have been tested and have low fertility. Light bulb goes off ! i have a referral mid may with the urologist.

since the age of 21 i have had non stop depression. i have always said to the docs i think i have a problem with testosterone and asked for blood tests. they are always normal. my life is great, so i cannot understand why i have depression. i am 13st of lean muscle, and very active, don't smoke or do drugs and drink maybe 3 beers a week. i already do the things people should do when they have depression.

i have some basic symptoms which never seem to change. they can be more severe on a day to day basis. at the moment it is one day good and one day bad etc.

what happens is like someone switching on a light. my body either comes to life or stops working.

this is what happens:

energy stops - tired, head in a fog, poor concentration
appetite goes
muscles decrease in size slightly - not as chunky
don't need to drink as much water
stamina drops off
not as strong
skin becomes drier
breathing tightens up (cant get a nice big breath full)
sexual desire decreases

i take one tablet of the AD effexor per day and carbomazapine (used to treat epilepsy commonly
nightly as a mood stabilizer. i have tried many timed to come off these things but no joy. my symptoms come back stronger and last almost permanently if i do.

one other thing, i had an undescended testicle and had it operated on when i was 9.

my thinking is i have primary late onset hypogonadism - low testosterone.

any help will be appreciated.
i am in the uk by the way.

Get blood tested, list on my post #40
Jan's BloodTest April13/2007 - Page 2
start new thread when you get the results or if you have more questions.

[TrembMan]

Hello...first of all sorry for my english,I'm brazilian and dont speak very well.

I'm on HRT for a year...and for about a 6 months...I'm felling in adrenal fatigue.A LOTTT of symptons.20 years old.
Hipothireodism.(1 year too)

my blood test.

Glicose 94 mg/dL 70 - 99 mg/dL
Insulina 7,3 μUI/mL 4,0 - 24,0
Colesterol Total 123 mg/dL
HDL - Colesterol 17 mg/dL - ((( Very loww)))
LDL - Colesterol 79 mg/dL
Homocisteína 8,8 μmol/L < 15,0
Lipoproteina (a) 14 mg/dL < 30 mg/dL
Iron 55 μg/dL de 59 até 159 μg/dL
Ferritina 83 ng/mL 22 a 322 ng/mL (sorry dont know the name in english)
Leucócitos 2.900 4.500 - 11.000 /μL
Neutrófilos 1.119 38,6 de 45,5 até 73,5 %
Eosinófilos 238 8,2 de 0,0 até 4,4 %
Basófilos 12 0,4 de 0,0 até 1,0 %
Linfócitos 1.325 45,7 de 20,3 até 47,0 %
Monócitos 206 7,1 de 2,0 até 10,0 %
Fibrinogênio 365,80 mg/dL 180,00 a 350,00 (WHAT IS THIS??)
Dehidroepiandrosterona (DHEA) 3,70 ng/mL 1,40 a 12,50 ng/mL (((LOWW))
Sulfato de Dehidroepiandrosterona 1.920 ng/mL 800 a 5.600 ng/mL ((LOW)))
Testosterona Total 3.994 ng/dL (800mg of test per week,I was doing this exam in my cycle)
Estradiol 15,3 pg/mL 0-42 (1/2 letrozol monday - fryday)
Progesterona 1,8 ng/mL < 1,0
SHBG 5,6 nmol/L 13-71nmol/L (stanozolol)
TSH 0,431 μUI/mL 0,350 a 5,500
T3 91 ng/dL 70 a 220 ng/dL (LOW)
T4 free 2,31 ng/dL 0,89 a 1,76 ng/dL ( 200mcg of T4 levotiroxin)
IGFBP3 2,71 μg/mL 3,40 a 7,80
IGF-1 (Somatomedina C) 204,0 ng/mL 127,0 a 424,0
Serotonina - 5HT 160,7 ng/mL de 117,5 até 193,3
Cortisol 20,0 μg/dL De 4 a 22 (7h AM)(BLOOD)


What do you think???

I dont have doc,I'm doing all ALONE.Need some Help.

I'm thinking about taking cortisone,if I'm fell better I continue....but in BRAZIL dont have HYDROcortisone....have predsolone and others,and I dont know about dosages.

[TrembMan]

please help!!

[steph]

There are so many good articles over here! Thank you!