Men's Health Forum: This is a discussion on Adrenal Thread within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; I know a overseas pharmaceutical broker who can ship hydrocortisone, prednisone, and Florinef to the US. The URL is at ...
I know a overseas pharmaceutical broker who can ship hydrocortisone, prednisone, and Florinef to the US. The URL is at hand pending the results of my Adrenal test.. I think Cortef is only about $30 for 100 10mg tablets.
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All male doctors need to be on a one year cycle of Proscar and Androcur. Maybe then, a hypogonadal man would be treated with the same care given to other patients.
I'm still evaluating salivary testing. Often there is quite a disparity between saliva, blood and urinary levels regarding cortisol and DHEA.
How would you explain low salivary cortisol levels and high DHEA levels (salivary 1200-1600) or DHEA-S in men not on DHEA supplemention. They all have uniformly low testosterone, estradiol and elevated progesterone levels. Thyroid function is normal based on FT3 and FT4 levels. Some men are hypertensive, 10-20 pounds overweight but are otherwise active. I don't know the plasma renin or aldosterone levels. Do you have any thoughts?
Judging by all of the tests I've had so far, I may be hypopituitary. My pre-treatment levels were:
Total T - 302 (241-827)
LH - 1.6 (1.2-8.6)
FSH - 1.6 (1.27-19.26)
Cortisol am - 17 (2-22) Range is skewed, cortisol should be upper twenties
DHEA - 262 (280-640)
FT3 - 3.1 (2.2-4.3)
FT4 - 6.3 (4.5-12)
ALL of the pituitary hormones are LOW. Could this be the cause of my hypogonadism. Could some cases of secondary hypogonadism actually be hypopituitary?
Judging by all of the tests I've had so far, I may be hypopituitary. My pre-treatment levels were:
Total T - 302 (241-827)
LH - 1.6 (1.2-8.6)
FSH - 1.6 (1.27-19.26)
Cortisol am - 17 (2-22) Range is skewed, cortisol should be upper twenties
DHEA - 262 (280-640)
FT3 - 3.1 (2.2-4.3)
FT4 - 6.3 (4.5-12)
ALL of the pituitary hormones are LOW. Could this be the cause of my hypogonadism. Could some cases of secondary hypogonadism actually be hypopituitary?
Have you had an MRI on your Pituitary Gland.
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Don't believe anything you hear and only half of what you see.
Phil
I had a pituitary MRI done. Showed nothing that would convince the endo to help me. I have low T, low LH, low FSH, and a questionable response to an ACTH stimulation test. It was nice to know I do not have a pituitary tumor, but my symptoms should have caused doctors to question if my low-normal results are really adequate to keep me healthy.
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All male doctors need to be on a one year cycle of Proscar and Androcur. Maybe then, a hypogonadal man would be treated with the same care given to other patients.
I had a pituitary MRI done. Showed nothing that would convince the endo to help me. I have low T, low LH, low FSH, and a questionable response to an ACTH stimulation test. It was nice to know I do not have a pituitary tumor, but my symptoms should have caused doctors to question if my low-normal results are really adequate to keep me healthy.
Yeah I'm a little frustrated how two docs, one being an endo can take a look at my symptoms and NOT order a pit mri. It would definately explain my symptoms and numbers. I read something recently that said a study was done on many autopsy reports showing that as many as 1 in 5 people have pit tumors. SO I guess these things are MUCH more common than reported (1 in 10,000)
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Albumin and TRT and Adrenal Fatigue
Quote:
Originally Posted by zadok
My FT level will not raise above the bare minimum, TRT, or no TRT. TT can be v high, but FT is always v low. It is not Estrogens causing the prob cause i have eliminated that. SHBG is v.v low also. Scientifically, the test must be going somewhere, or binding to something else, which must be high. My question is what else does test bind to? My Albumin is high normal 46nmol/l (35-50), however i dont think that would be causing this problem, what else could it be?
Total testosterone consists of:
1. Testosterone strongly bound to Sex Hormone Binding Globulin - inactive
2. Testosterone weakly bound to Albumin - potentially active
3. Testosterone which is free - fully active
Measuring Bioavailable Testosterone (free and weakly bound) is important when questioning the effectiveness of TRT, if free T is low.
Albumin makes up about 70% of the circulating protein in the blood. It is highly important to maintain blood pressure and to transport other substances.
By weakly binding Testosterone, Albumin protects Testosterone from being destroyed in the liver. Free Testosterone itself may last only about 70 minutes before being destroyed. Testosterone bound to Albumin may be considered the body's way to create a natural extended-release form of testosterone - just as medications often come in an extended-release version.
High albumin level is primarily associated with dehydration.
Dehydration and high albumin level is one possible clue that adrenal fatigue or insufficiency is occurring. In adrenal fatigue or insufficiency, besides cortisol and DHEA, not enough aldosterone is produced. Aldosterone is important in maintaining sodium level, fluid and salt balance in the body, maintaining blood pressure.
Adrenal fatigue or insufficiency may contribute to sexual dysfunction (and other conditions) and can lower testosterone production.
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