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Men's Health Forum: This is a discussion on alpha reductase activity - link between DHT and insulin resistance? within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; You may have noticed a post recently regarding Finasteride and within it there is mention of disturbed Alpha 5-reductase enzyme ...

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Old 01-30-2007, 06:27 AM
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Default alpha reductase activity - link between DHT and insulin resistance?

You may have noticed a post recently regarding Finasteride and within it there is mention of disturbed Alpha 5-reductase enzyme activity and how this might impair cortisol production.
I also recall that alpha 5-reductase is the enzyme responsible for creating DHT. So I'm looking to confirm the link between alpha-5 reductase activity and the typical phenomenon of balding men with lots of body hair, little head hair, and middle body obesity.

Is it true that the high level of alpha 5 reductase activity is giving these men both high DHT AND cortisol levels?. Whereby the higher cortisol levels impair insulin activity and cause middle body obesity.

I have both gynecomastia and some adrenal fatigue. I'm curious as to the prospect of using something that will increase alpha 5 reductase activity to increase DHT (which will antagonise the excessive E2) and also give me the increased Cortisol my body craves.....
Has anyone thought to do this? If so what drug is used and can anyone give a brief run down on it?

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Old 01-30-2007, 11:42 AM
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Default Re: alpha reductase activity - link between DHT and insulin resistance?

i noticed the same thing- lots of guys are bald, hairy and fat, to put it blunty.

i believed that elevated dht and e2 in my case has contributed to weight gain and hairloss

nasty combination
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adrenal fatigue , cortisol , dht , finasteride , gynecomastia , insulin

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