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  #1 (permalink)  
Old 06-18-2009, 11:46 PM
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Default Best E2 level

At what E2 level have you felt the best and had the strongest erections.

I
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Old 06-19-2009, 12:04 AM
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Default Re: Best E2 level

Quote:
Originally Posted by brettj86 View Post
At what E2 level have you felt the best and had the strongest erections.

I
Lower the SHBG lower the e2
higher the SHBG the higher e2 can be

ultrasensitve (mid range)
sensitive 20-30
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Old 06-19-2009, 01:28 AM
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Default Re: Best E2 level

My understanding from talking with Dr. M is that the absolute number is not as important as the ratio of T:E. He seems to feel that ideal is between 20:1 or 30:1. All I can say is that my E2 is and has been very low (~7) for awhile with fairly high T and I feel like absolute dog shit in a variety of ways, not the least of which is my lack of libido.
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Old 06-19-2009, 07:45 AM
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Default Re: Best E2 level

Getting e2 up is the easy part keeping it in check is the biggest challenge.
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Old 06-19-2009, 08:46 AM
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Default Re: Best E2 level

Quote:
Originally Posted by EIC View Post
My understanding from talking with Dr. M is that the absolute number is not as important as the ratio of T:E. He seems to feel that ideal is between 20:1 or 30:1. All I can say is that my E2 is and has been very low (~7) for awhile with fairly high T and I feel like absolute dog shit in a variety of ways, not the least of which is my lack of libido.
That's interesting. I just watched the Dr. John video last night and he says just the opposite. He said that the ratio is not important and he just pays attention to the absolute numbers. Of course, I guess that is not surprising, as I have seen several areas where Dr. John and Dr. Shippen differ greatly. I guess it just goes to show that no one completely understands all that there is to know about the very complex issue of hormones. Or perhaps it is just that opposite ideas both work. It probably depends on the person who is being treated.
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Old 06-19-2009, 09:07 AM
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Default Re: Best E2 level

The end result is that you can look at all the clincal data on once there are always going to be exceptions to the rule. In a clinical setting I am dealing with some of the complex cases that dr's do not even want to touch such as
Adrenals antibodies, secondary hypothyroidism due to adrenal insufficiency, testosterone resistance (androgen resistance), people that are slapped on antidepressants when the source was adrenal insufficeny due to improper thyroid meds. I am sure Dr M has seen his share as well. To get proper treatments and results the Dr will be have to willing to tweak the protocol and think out side the box of traditional medicine, but stay with in the guidelines.
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Old 06-19-2009, 11:30 AM
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Default Re: Best E2 level

For me the best levels of E2 are when you get some strong night time and morning wood from rem sleep. When I don't get them on arimidex I know I am going down to low. I don't chase ratio's and labs for this I go by how I feel and my wood. The labs are just tool there are no set labs that give me good wood E2 changes all the time and one needs to keep a log on what they are taking and how they feel to keep it in the sweet spot.
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Old 06-19-2009, 10:12 PM
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Default Re: Best E2 level

Quick adex question.

If you are currently using adex, and realize you have knocked your E2 too low, and just stop taking adex. How many days does it take for your E2 levels to go back to where they would be if you werent taking adex at all???

Theoretical Question #2: Suppose you took a single full dose of letro, and knocked your E2 down 95+%. How many days do you think it would take to recover to normal E2 levels?
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Old 06-19-2009, 10:57 PM
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Default Re: Best E2 level

Problem is that people on weekly injections can have very high E2 at the time of the blood draw and very low (E2) 12 or 24 hours latter.

If the weekly average is in the (more or less) right place ok, otherwise there is a problem.

The big deal is that one would have to draw blood 7x within a week to figure it out.

That is why men who use transdermal daily testosterone have an edge.
Their measurements of E2 have much higher chance of being correct.

That is why I use EOD injections, so when I measure E2 I have a better chance to get the actual number.

I have used the

Estradiol, Ultrasensitive, LC/MS/MS (30289X)

so many times and newer got <2 readings.

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Old 06-20-2009, 12:21 AM
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Default Re: Best E2 level

Quote:
Originally Posted by hardasnails1973 View Post
Getting e2 up is the easy part keeping it in check is the biggest challenge.
If you're on HRT, yes; if you are not (like me) then getting E2 up can be hard. Dr. M has mentioned HCG as a possibility, but we are waiting to see how things look when all the rough parts are smoothed out. I personally can't remember ever having the super high libido that most men experience, even as an adolescent/college student. I suspect that I just don't produce much aromatase.
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