Men's Health Forum: This is a discussion on E2 and DHT spikes within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; As most know E2 and DHT increase rapidly in the first 36 hrs following a T injection and fall off ...
As most know E2 and DHT increase rapidly in the first 36 hrs following a T injection and fall off more slowly in a logarithmic (or is it exponential?)function over time. Anyway the bottom line is that E2 and DHT are only high for a short time in the first part of the week. Since the aromatizarion of T takes place in adipose tissue, those of ushaving less fat will need less AI doseage. I wrote up a proposed doseing plan for Arimidex a while ago that addresed the E2 spike issue. I think its good for me (5-10, 145lbs) to take 0.5mg the evening following the T injection and that wil take care of it for the week. Maybe a 1/4mg on day 5 to ake care of the hcg induced spike.
Now I`m wondering just how safe it is to ignore the DHT spike? I`ve heard all the stories about Finsasteride but were any of the cases involving a single small dose timed with the T injection ? Since the Endo is playing resident with me and odrering the tests I want I think I will run this past him too. I believe there is sufficient evidence concerning the role of DHT in prostate problems to justify doing something about high DHT levels brought about by running T levels in the uooer third of the normal range.
Im not sure E2 and BF can be directly coorelated. You would have to see me to understand. As of now Im about 6 - 7% BF. Full 6 pack, veins protruding from lower abs. My e2 = 43.
I think everyone has a different expression of the aromatase enzyme, regardless of BF levels.
Now I do believe that increases in BF will increase E2. However, I just wanted to point out that everyone has a higher/lower base E2 level at a low BF%.
I don't think its ever a good idea to try and guestimate an arimidex dosage. Its best to go by BW and shoot for a number 17 - 25, preferably closer to the lower end of that scale.
I think the same goes for DHT. Everyone has a different base DHT level and will respond totally different. Some might see a small tick in a rise from 100mg inject, others may go well above the upper range.
That sounds bout rite. But if you compare 250 lb fat sedentary guys to thin types I`m sure they will statistically run significantly higher. I mention it more as a guideline to the EOD users.
The thing that interests me is the DHT and lack of control. For me the whole thing is to optimize hormonal levels.
Before HRT my E2 levels were 217 pmol/L range (0-206), at 8% bf, although that was with supplementing with 100mg DHEA/day which may have squewed the results. I have a six pack and am quite vascular.
I'm not sure what my E2 levels are now, but they are probably higher. I'm struggling to keep my E2 sides down while on HCG 250IU EOD, and was taking 100mg test a week but had to drop it.. 25mg/day of Aromasin isn't strong enough to keep sides away.
I have Arimidex and Letrozole coming. Hopefully they will be stronger.
When I was on Gels my DHT and E2 levels were over the top my DHT was 3 x's above the top of the range. For me Gels were the worst for E2 and DHT levels. Now that I do shots and HCG my DHT is down at mid range. My E2 is much less a problem and the best gauge for E2 being at the right levels is night time and morning wood if you have this and it's strong your at the right range. Still when I test T levels I do my E2.
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Don't believe anything you hear and only half of what you see.
Phil
Before HRT my E2 levels were 217 pmol/L range (0-206), at 8% bf, although that was with supplementing with 100mg DHEA/day which may have squewed the results. I have a six pack and am quite vascular.
I'm not sure what my E2 levels are now, but they are probably higher. I'm struggling to keep my E2 sides down while on HCG 250IU EOD, and was taking 100mg test a week but had to drop it.. 25mg/day of Aromasin isn't strong enough to keep sides away.
I have Arimidex and Letrozole coming. Hopefully they will be stronger.
Use the arimidex.
It is your best bet.
Aromasin may actually be healthier/safer, but it is nowehere near as effective as arimidex.
How much T and hcG do you inject/how often/what are results.
Aromasin may actually be healthier/safer, but it is nowehere near as effective as arimidex.
How much T and hcG do you inject/how often/what are results.
Thanks
I was taking 100mg test enanthate/week, 28mg EOD IM, with 250 IU HCG EOD SC. I originally started with a low dose of Aromasin 6.25mg EOD because I didn't want to overshoot. I've since progressed up to 25mg ED, and have had to drop the test, due to E2 sides.
The E2 sides became apparant the first couple days with test only, then became worse with HCG addedthe next week. I only started 2-3 weeks ago.
So far I am feeling worse. Much more fatigued, ED, BPH, sore wrists, and bloating. I am starting to feel a little better since dropping the test. Until I get the Adex and Letro I am going to hold off on the HCG as well (till next week), while taking 25mg Aromasin/day.
I am shocked that I am so sensitive to E2. I'm guessing I may have low SHGB. My doctor did not want to test it. I assumed lean people always had low E2 levels. I'm guessing this is not the case.
I had wondered if I overshot my Aromasin dose resutling in too low of E2, but I don't think I would have the bloat, and BPH problems in that case. I'm not scheduled for blood work till the middle of november.
I was taking 100mg test enanthate/week, 28mg EOD IM, with 250 IU HCG EOD SC. I originally started with a low dose of Aromasin 6.25mg EOD because I didn't want to overshoot. I've since progressed up to 25mg ED, and have had to drop the test, due to E2 sides.
The E2 sides became apparant the first couple days with test only, then became worse with HCG addedthe next week. I only started 2-3 weeks ago.
So far I am feeling worse. Much more fatigued, ED, BPH, sore wrists, and bloating. I am starting to feel a little better since dropping the test. Until I get the Adex and Letro I am going to hold off on the HCG as well (till next week), while taking 25mg Aromasin/day.
I am shocked that I am so sensitive to E2. I'm guessing I may have low SHGB. My doctor did not want to test it. I assumed lean people always had low E2 levels. I'm guessing this is not the case.
I had wondered if I overshot my Aromasin dose resutling in too low of E2, but I don't think I would have the bloat, and BPH problems in that case. I'm not scheduled for blood work till the middle of november.
Thoughts?
Those are high E2 sides.
Aromasin just isn't effective enough for you, you need adex.
Get back on T and get adex working. Start off with 1mg per week total, split up EOD.
I am walking proof at 6% BF with a baseline E2 reading of 43(that is on no drugs) that bodyfat and E2 are of little coorelation.
Yea I`m beginning to think that BF and E2 dont corelate all that well too.
Yep. No impact on BASELINE levels.
However, as one gains weight/loses weight, it will fluctuate from baseline levels.
I guy naturally at 30 E2 that is thin will see an e2 level go up if he gains weight.
So we can make a judgement that a good first line of defense against E would be to simply lose weight.
However, the monkey wrench in the engine is that having high E2 levels makes it hard to lose weight.
This is why we start with adex. The theory is that as E2 goes down and one shifts to a more favorable T/E ratio, one will lose weight. Then one may be able to lower dosage of arimidex or possible be weened off.
E2 and DHT spikes 
Linear Mode
