Men's Health Forum: This is a discussion on High Norepinepherine & Erectile Dysfunction within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; I'm not greek, bro. I'm italian......
I can tell you that when I take too much Adderall (amphetamine), the NE spike is so bad it can trigger anything to a partial to full ejaculation without even thinking about sex......
When I was in college I had a friend with benefits and she told me her boy friend could not get it up if he took Ephedrine products. He used to work at a bar and he would take those pills the gas stations used to carry to stay a wake. Needless to say I helped her out with that problem right before she went off to see her boy friend!!!! So yes I have heard of it before. So if your adrenal system is pumping out too much of it then it could do the same thing as taking too much Ephedrine ! I know when my Doctor first put me on high blood pressure medicine the first medicine he put me on if I had so much as a single beer it shut down my ability to get an errection. Needless to say that medication was changed in less then 2 weeks time! Even though I am married now me and the wife love a healthy sex life and we both like to have a drink or two at random.
If itis natural problem you need to look into biofeedback and look at diet becasue stress raise's your epi levels!
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NE is a potent vasoconstrictor, so yes. Alpha1 antagonists systemically block the action of NE at the presynaptic neuron at smooth vascular muscle and PDE5 inhibitors help maintain the action of nitric oxide, a potent vasodialator, in the penis.