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Men's Health Forum: This is a discussion on Injections VS gels within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; I have "fought" the baldness problem for years with DHT . I just went to a "renouned" Dermatologist here in ...

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  #11 (permalink)  
Old 04-25-2005, 07:17 PM
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I have "fought" the baldness problem for years with DHT. I just went to a "renouned" Dermatologist here in Houston and was told that essentially there is nothing that can be done to reverse baldness since one is predisposed genetically for baldness. If one is 25 and the genetic makeup says that he will be bald by age 40, then DHT will accelerate it, but nothing can really change the end results. I had to have have transplants early on in which the plastic surgeons stated the exact same these concerning baldness. Now that I am 52 and STILL taking testosterone for muscle mass, I would be completely bald if it wasn't for my transplanted areas. Propecia nor any of the other DHT fighting drugs would have made a difference........

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Old 04-26-2005, 12:19 PM
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Quote:
Originally Posted by gemini
I was under the impression that injectible T caused higher Estrogens than transdermals.
Nope. Why? Because the adipose tissue (fat) contains higher concentrations of the aromatase enzyme, which converts testosterone to estradiol.
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Old 04-26-2005, 12:51 PM
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Quote:
Originally Posted by mranak
Nope. Why? Because the adipose tissue (fat) contains higher concentrations of the aromatase enzyme, which converts testosterone to estradiol.
What about the fact that the injectible T causes a faster rise in T levels thereby causing a bigger conversion to Estrogen?
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Old 04-26-2005, 02:31 PM
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I have done both and a mix for gel and shots. I find that the shots convert faster then the gels. But it does not matter I have to take something everyday to keep my E2 in check.
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Old 04-27-2005, 04:09 AM
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Quote:
Originally Posted by earthdog
One of the things that testosterone converts to is DHT. That is the hormone that is, to quote Swale, "responsible for All Things Male." But DHT is also responsible for male pattern baldness. The skin contains an enzyme that coverts testosterone to DHT. Therefore, testosterone applied transdermally (through the skin) will have a higher conversion rate to DHT than injected testosterone will, and therefore will be somewhat more likely to produce male pattern baldness, if you are genetically predisposed to male pattern baldness. If you are not genetically predisposed to it, then there is no problem there. Injected testosterone will also convert to DHT, but at a lower rate than transdermally applied testosterone.

I don't know if DHT can also cause acne. My guess is that it can. Perhaps someone can answer that.
Acne is a disorder of keratinization, meaning the development of cells lining the sebaceous gland is faulty.

These cell walls are sticky, binding together, plugging the gland rather than easily exfoliating themselves onto the surface.

Despite the presence of this plug, the sebaceous glands, triggered by DHT, the active form of testosterone, continue to secrete sebum.

so to your question, yes DHT can and will trigger acne in many who are predisposed to it.
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Old 04-27-2005, 05:45 AM
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Quote:
Originally Posted by GDSGFT
Acne is a disorder of keratinization, meaning the development of cells lining the sebaceous gland is faulty.
These cell walls are sticky, binding together, plugging the gland rather than easily exfoliating themselves onto the surface.
Despite the presence of this plug, the sebaceous glands, triggered by DHT, the active form of testosterone, continue to secrete sebum.

Holy camoly !!!!! say that again ?
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Old 04-27-2005, 07:07 AM
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Quote:
Originally Posted by GDSGFT
Acne is a disorder of keratinization, meaning the development of cells lining the sebaceous gland is faulty.

These cell walls are sticky, binding together, plugging the gland rather than easily exfoliating themselves onto the surface.

Despite the presence of this plug, the sebaceous glands, triggered by DHT, the active form of testosterone, continue to secrete sebum.

so to your question, yes DHT can and will trigger acne in many who are predisposed to it.
That sounds like me. Faulty sebaceous lining cells. My pores clog no matter what I use or how often I wash.

Does accutane somehow reverse or correct this process? I'm considering using accutane.
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Old 04-27-2005, 07:27 PM
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Accutane causes the glands to reduce, or in some cases STOP, producing the oils. This is a permanent thing. It also causes LOTS of dryness when on it. I just got done with a 5 month regimen at a reduced dosage (had to go low cause of the side effects...I'd shit myself at higher doses lol!) Even at a less than optimal dose most of my acne is gone. ALL of the large nodules are gone. Worth it. Sucks while on but afterwards you're very happy.
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Old 05-01-2005, 02:23 PM
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Gemini's got it right. Test cyp will increase E levels dramatically when it is overdosed. This increases the activity of the aromatase enzyme.

But generaly transdermals elevate E moreso (compared to appropriate test cyp dosing) because of the presence of the aromatase enzyme in the adipose tissue. It also tends to rise over time.
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Old 05-01-2005, 04:29 PM
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I have had acne problems all my life and was extremely concerned about this being aggravated by TRT. I no longer have an acne problem since I discovered "The Regimin" at www.acne.org. I have altered it just a little but what I do is was my face in the shower with a soap called Basic. Then after drying I apply the gel developed by the owner of the site(it is dirt cheap and last for a couple of months). It is 5% Ben. Perox. You must use it liberally and it dries on clear. I apply it to my problem areas only. Then use the mosturizer, brand Basic(it does not clog pores). In the evening just before going to bed I use 2""Clear and Clean" Salic Acid pads on the problem areas and let it dry. That is it! Once you start using the Regimin, it only takes a couple of extra minutes out of your day. Worked like a charm for me. TRT has not caused any relapses.
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accutane , acne , aromatase , body , bodybuilding , bodybuilding.com , cycle , dht , estradiol , estrogen , growth , hair , information , lab , mass , muscle , oral , pain , propecia , sex , site , skin , test , testosterone , trt

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