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Old 09-08-2008, 10:55 PM
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Default less E2 = more DHT?

All,

Is this logic correct? The reason I ask is because I have cranked up my liquidex since switching to injections from pellets and once I added liquidex, I feel great. I haven't gotten to the lab yet though. Is there any truth that lowering aromatase activity leaves more testosterone to convert to DHT ---- because my back has seriously broken out!!! Thanks.
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Old 09-09-2008, 01:48 AM
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Default Re: less E2 = more DHT?

in males, progesterone opposes DHT.
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Old 09-09-2008, 11:14 AM
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Default Re: less E2 = more DHT?

Quote:
Originally Posted by HeadDoc View Post
in males, progesterone opposes DHT.
Thanks HeadDoc,

If testosterone does not aromatize, is it left in a free state, or does it still have a chance to bind to SHBG?
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Old 09-09-2008, 02:12 PM
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Default Re: less E2 = more DHT?

Read this link..
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Old 09-09-2008, 08:56 PM
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Default Re: less E2 = more DHT?

Quote:
Originally Posted by clloyd View Post
Thanks HeadDoc,

If testosterone does not aromatize, is it left in a free state, or does it still have a chance to bind to SHBG?
testosterone can aromatize and convert to E2. Testosterone can metabolize to DHT. Each of these actions requires a different enzyme.
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Old 09-12-2008, 04:08 PM
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Default Re: less E2 = more DHT?

DHT and estradiol are both metabolites of testosterone. Reducing conversion of T to E, will increase total testosterone. Increased testosterone means more available substrate to be converted to DHT.
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Old 09-12-2008, 06:24 PM
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Default Re: less E2 = more DHT?

its the bioavailable testosterone that converts to dht more then anything..
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