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Old 01-26-2007, 06:38 PM
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Default My Testosterone, Estradiol and DHT blood results

I recently underwent a routine blood test where they measure hematology and blood chemistry and I asked the doctor to request a testorone, estradiol and DHT test as well.

I also asked for SHBG, free testosterone, DHEA and all the rest of the hormones, but the doctor started freaking out, telling me I have to go to an endroconologist for that. In fact, the lab was supposed to test my thyroid, but they failed to do so. I'm still trying to find out where the communication broke down.

Anyway, here are the partial hormonal results. I plan to get more extensive tests done in the near future, but I'm not going through that doctor again.

Testosterone - 6.29 (1.75-7.81 ng/ml)
DHT 305 (160-660 pg/ml)
Estradiol 17 (20-75 pg/ml) This is for females as the male normal range was not listed.

On the other blood tests, everything was in normal range except Mean Platelet Volume (MPV), which was 7.2 (7.4-10.4). From what I've read, it is worse to have a higher than normal MPV than lower because that puts you at greater heart attack and stroke risk.

In my urine test, everything was normal except for the following: Urine was "cloudy" where it is supposed to be "clear"; I had 1-3 white blood cells in my urine where I'm supposed to have 0-1; and I had a "few" urates when I'm supposed to have "none".

It should be noted that I've been fighting an ear infection and have been on antibiotics.

Any feedback?
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Old 01-26-2007, 09:33 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by The_Skeptic
I recently underwent a routine blood test where they measure hematology and blood chemistry and I asked the doctor to request a testorone, estradiol and DHT test as well.

I also asked for SHBG, free testosterone, DHEA and all the rest of the hormones, but the doctor started freaking out, telling me I have to go to an endroconologist for that. In fact, the lab was supposed to test my thyroid, but they failed to do so. I'm still trying to find out where the communication broke down.

Anyway, here are the partial hormonal results. I plan to get more extensive tests done in the near future, but I'm not going through that doctor again.

Testosterone - 6.29 (1.75-7.81 ng/ml)
DHT 305 (160-660 pg/ml)
Estradiol 17 (20-75 pg/ml) This is for females as the male normal range was not listed.

On the other blood tests, everything was in normal range except Mean Platelet Volume (MPV), which was 7.2 (7.4-10.4). From what I've read, it is worse to have a higher than normal MPV than lower because that puts you at greater heart attack and stroke risk.

In my urine test, everything was normal except for the following: Urine was "cloudy" where it is supposed to be "clear"; I had 1-3 white blood cells in my urine where I'm supposed to have 0-1; and I had a "few" urates when I'm supposed to have "none".

It should be noted that I've been fighting an ear infection and have been on antibiotics.

Any feedback?
What are you complaining about?
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Old 01-26-2007, 11:32 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by JanSz
What are you complaining about?
I'm not really complaining, just wanted to get some feedback. I'm wondering if my E2 is at a decent level or is it too low? Frankly, I was surprised it was that low.

I'm also curious about the numbers they consider normal ranges. They've very different from what I've seen here.
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Old 01-27-2007, 10:53 AM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by The_Skeptic
I recently underwent a routine blood test where they measure hematology and blood chemistry and I asked the doctor to request a testorone, estradiol and DHT test as well.

I also asked for SHBG, free testosterone, DHEA and all the rest of the hormones, but the doctor started freaking out, telling me I have to go to an endroconologist for that. In fact, the lab was supposed to test my thyroid, but they failed to do so. I'm still trying to find out where the communication broke down.

Anyway, here are the partial hormonal results. I plan to get more extensive tests done in the near future, but I'm not going through that doctor again.

Testosterone - 6.29 (1.75-7.81 ng/ml)
DHT 305 (160-660 pg/ml)
Estradiol 17 (20-75 pg/ml) This is for females as the male normal range was not listed.

On the other blood tests, everything was in normal range except Mean Platelet Volume (MPV), which was 7.2 (7.4-10.4). From what I've read, it is worse to have a higher than normal MPV than lower because that puts you at greater heart attack and stroke risk.

In my urine test, everything was normal except for the following: Urine was "cloudy" where it is supposed to be "clear"; I had 1-3 white blood cells in my urine where I'm supposed to have 0-1; and I had a "few" urates when I'm supposed to have "none".

It should be noted that I've been fighting an ear infection and have been on antibiotics.

Any feedback?
In my units your T is 629 ng/dl top of your range is 781 so your in the upper 1/3 of your lags range. To tell if your E2 Estradiol is to low we need your SHBG if your under 25 then your E2 is good. How do you feel do you get morning wood and can your have sex.
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Old 01-27-2007, 03:59 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by pmgamer18
In my units your T is 629 ng/dl top of your range is 781 so your in the upper 1/3 of your lags range. To tell if your E2 Estradiol is to low we need your SHBG if your under 25 then your E2 is good. How do you feel do you get morning wood and can your have sex.
Hi Phil;
and others who can/will help with answer.
Please tell me what you know or point me to previus discussions about correct E2 levels as function of a level of other hormones, in this case SHBG but probably there are other. It would be great if there were some Dr Marianco's posts on this, or Dr John on the other board.

I also thought that there were hints on how to run TRT to minimize E2 and DHT problems.
My DHT is usually high, I stopped using Avodart hoping that instructions come soon.
My (unsuportedt) guess was that it was about not exceeding FreeT more than 250, and using DIM and I3C. Specially I3C is my suspect, it act more broadly than DIM and possibly that is a reason that it regulates Total estrogens and may be also DHT.

Btw, Phil, FreeT=250 is quite generous and not really very limiting for what we are attempting here. Just looking at FreeT makes a point that the desired good Testosterone level is different for different people and depends heavily on their SHBG level.
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Old 01-27-2007, 05:09 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by JanSz
Hi Phil;
and others who can/will help with answer.
Please tell me what you know or point me to previus discussions about correct E2 levels as function of a level of other hormones, in this case SHBG but probably there are other. It would be great if there were some Dr Marianco's posts on this, or Dr John on the other board.

I also thought that there were hints on how to run TRT to minimize E2 and DHT problems.
My DHT is usually high, I stopped using Avodart hoping that instructions come soon.
My (unsuportedt) guess was that it was about not exceeding FreeT more than 250, and using DIM and I3C. Specially I3C is my suspect, it act more broadly than DIM and possibly that is a reason that it regulates Total estrogens and may be also DHT.

Btw, Phil, FreeT=250 is quite generous and not really very limiting for what we are attempting here. Just looking at FreeT makes a point that the desired good Testosterone level is different for different people and depends heavily on their SHBG level.
I just know about low SHBG from Dr. John but if you read about what SHBG does to T and E2 then it makes sense. The higher your SHBG the more your Tand E2 is bound up.
Who has a Free T level of 250 I hear Shippen saying a CFT of 160 pg/ml is normal but my labs Free T range is 8.8 to 27 pm/ml have no Idea what the difference is mine is a lab result and his is CFT. My Dr. told me CFT is not accurate. I only use Quest to check my E2 the rest of my tests are done at a loco lab that is much better then Quest. The lab is BioTech there Free T test is the best out.
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Old 01-27-2007, 06:42 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by pmgamer18
I just know about low SHBG from Dr. John but if you read about what SHBG does to T and E2 then it makes sense. The higher your SHBG the more your Tand E2 is bound up.
Who has a Free T level of 250 I hear Shippen saying a CFT of 160 pg/ml is normal but my labs Free T range is 8.8 to 27 pm/ml have no Idea what the difference is mine is a lab result and his is CFT. My Dr. told me CFT is not accurate. I only use Quest to check my E2 the rest of my tests are done at a loco lab that is much better then Quest. The lab is BioTech there Free T test is the best out.
Most of laboratories are doing FreeT wrong. Explained here:
http://jcem.endojournals.org/cgi/reprint/86/6/2903.pdf
Your laboratory is no different. Now you are stuck with the number that really have no meaning.
I have from LabCorp junk numbers on my FreeT, so I am not much better of ether, until next test.
Possibly the best, at this point, would be to give up on asking for FreeT test.
Just get the TT, Albumin and SHBG, and you can calculate the FreeT number your self.
Do not ask the doctor to do it, he only will get confused.
Do you own due diligence so you can be comfortable with this issue.

You said that you have a chart that Dr Shippen uses, look at it.
If it is the same that I have seen, it does not use Albumin as a variable to make that chart little simpler to use. But at the bottom there is a reference that explains the theory behind it.
That same method is used in calculator available here:
http://www.issam.ch/freetesto.htm
the reference method is on the second page, here on second line:
http://www.issam.ch/freetesuit.htm
The calculator, because it uses Albumin, is somewhat more accurate then Dr Shippen's chart.
Many things changed in last 23 years.
Actually the chart and the calculator are somewhat obsolete now. The newer theory is here:
http://www.atypon-link.com/WDG/doi/p...5/JLM.2006.050
I just wish I knew how to use it.

-----------
It would help if we could get Dr Marianco to chime in on this subject or Dr John.
----------------
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Old 01-27-2007, 07:25 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by JanSz
Most of laboratories are doing FreeT wrong. Explained here:
http://jcem.endojournals.org/cgi/reprint/86/6/2903.pdf
Your laboratory is no different. Now you are stuck with the number that really have no meaning.
I have from LabCorp junk numbers on my FreeT, so I am not much better of ether, until next test.
Possibly the best, at this point, would be to give up on asking for FreeT test.
Just get the TT, Albumin and SHBG, and you can calculate the FreeT number your self.
Do not ask the doctor to do it, he only will get confused.
Do you own due diligence so you can be comfortable with this issue.

You said that you have a chart that Dr Shippen uses, look at it.
If it is the same that I have seen, it does not use Albumin as a variable to make that chart little simpler to use. But at the bottom there is a reference that explains the theory behind it.
That same method is used in calculator available here:
http://www.issam.ch/freetesto.htm
the reference method is on the second page, here on second line:
http://www.issam.ch/freetesuit.htm
The calculator, because it uses Albumin, is somewhat more accurate then Dr Shippen's chart.
Many things changed in last 23 years.
Actually the chart and the calculator are somewhat obsolete now. The newer theory is here:
http://www.atypon-link.com/WDG/doi/p...5/JLM.2006.050
I just wish I knew how to use it.




-----------
It would help if we could get Dr Marianco to chime in on this subject or Dr John.
----------------

I read those all those links and it was confusing as hell. They didn't check my SHBG, but they did check my albumin, which was 4.7 (3.2-5.3 gm/dl). I guess without the SHBG, I still can't determine my Free Test.
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Old 01-27-2007, 11:03 PM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by The_Skeptic
I read those all those links and it was confusing as hell. They didn't check my SHBG, but they did check my albumin, which was 4.7 (3.2-5.3 gm/dl). I guess without the SHBG, I still can't determine my Free Test.
Without SHBG you cannot do calculation of FreeT. Small variation in SHBG make a big difference to end results.
It is not the same with Albumin.
Dr Shippen's chart is not using Albumin, but,
it is assumed there that Albumin=4.3
In your case, speaking of Albumin, yours is higher than 4.3, you have 4.7, that is little bit of a good news. Testosterone that is bound to Albumin is still bio-available, and eventually it counts.
-------------------------
I learn all this only recently.
I included SHBG on the list when I ask for a script for my last blood test.
Guess what, they skipped SHBG and screw me up (little bit) with cortisol.
I am on this road for over 4 years, had number of tests and newer had my SHBG checked.
--------------------------
Are you by any chance chemist or know somebody who could be able to help and use that new ,2006 method,to do our FreeT calculations?
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Old 01-28-2007, 05:49 AM
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Default Re: My Testosterone, Estradiol and DHT blood results

Quote:
Originally Posted by JanSz
Without SHBG you cannot do calculation of FreeT. Small variation in SHBG make a big difference to end results.
It is not the same with Albumin.
Dr Shippen's chart is not using Albumin, but,
it is assumed there that Albumin=4.3
In your case, speaking of Albumin, yours is higher than 4.3, you have 4.7, that is little bit of a good news. Testosterone that is bound to Albumin is still bio-available, and eventually it counts.
-------------------------
I learn all this only recently.
I included SHBG on the list when I ask for a script for my last blood test.
Guess what, they skipped SHBG and screw me up (little bit) with cortisol.
I am on this road for over 4 years, had number of tests and newer had my SHBG checked.
--------------------------
Are you by any chance chemist or know somebody who could be able to help and use that new ,2006 method,to do our FreeT calculations?

I was just looking at my past tests from 12 years of being on TRT and not once did they ever test for SHBG. Not once. What the hell is wrong with these doctors that they neglect such an important thing?
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