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Old 04-16-2007, 08:20 PM
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Default Please interpret these labs and give opinions

These labs are my most recent and are what I typically show without any form of treatment whatsoever. The most dominant things I am trying to fix are in order of importance:

Depression
Insomnia
Energy
Motivation
Memory
Erections

I also have an erratic heartbeat which feels like I have been scared and then it slows down..and does that cycle over and over all day long. Usually twice within each minute. Bloodwork is as follows:

Labs done 2 weeks ago

E2 51 (2-50) (high flag)
TSH 1.471 (0.350-5.500)
FSH 1.3 (1-12)
LH 4.1 (2-12)
Prolactin 6.2 (3-20)
Free Testosterone 130 (47-244)
%Free Testosterone 3.2 (1.6-2.9) (high flag)
Testosterone 412 (280-1070)
SHBG 12 (13-71) (low flag)
Dihydrotestosterone 413.9 (155-553)

Also, my most recent adrenal labs showed:

ACTH 61 (4-35) (high flag)
Cortisol 17 (3-17) (high flag)
TSH 1.243 (0.350-5.500)

Thyroids usually look mid range

Any input is appreciated

God Bless,
Chris
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Old 04-16-2007, 09:04 PM
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Default Re: Please interpret these labs and give opinions

Hi Chris yep it's me posting from Meso. You need to get your E2 down with an SHBG this low your E2 is dam high. If you can't get some Arimidx they sell it here in a liq. form.
http://www.ag-guys.com/store/product...=16134&cat=248
Or get some Indolplex/DIM and take one tablet at dinner time if your E2 comes down your first thing you will see is morning wood.
http://www.ritecare.com/prodsheets/PHY-15336.html
But then we have talked about this before. I think I also gave you this link at the H2 group.
http://jcem.endojournals.org/cgi/content/full/89/3/1174
Getting your E2 down will bring up your T levels and can lower your cortisol levels.
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Old 04-16-2007, 09:06 PM
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Default Re: Please interpret these labs and give opinions

vaiisking, i believe we are both in the same situation with regards to chronic ED and "shrinkage"?

Your problem is clear cut here. E2 is your issue and you need to bring that value down a good bit. This correlates with both SHBG and TSH, so fixing this should free up allot more "free" testosterone in your body and improve erection quality and such like.
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Old 04-16-2007, 09:19 PM
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Default Re: Please interpret these labs and give opinions

Quote:
Originally Posted by Megazoid
vaiisking, i believe we are both in the same situation with regards to chronic ED and "shrinkage"?

Your problem is clear cut here. E2 is your issue and you need to bring that value down a good bit. This correlates with both SHBG and TSH, so fixing this should free up allot more "free" testosterone in your body and improve erection quality and such like.
Everything they tell you i agree 100% lowering estrogen will also increase Lh back to tell your brain to produce more testosterone also lowering e2 will help prevent insuin resistance
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Old 04-16-2007, 10:04 PM
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Default Re: Please interpret these labs and give opinions

My doctor gave me Raloxifene samples....a months supply at 60mg/day tablets. Is this similar to arimidex? Not heard anything from Raloxifene. My understanding is that it is a SERM, which is different from Arimidex, but I'm not exactly sure how.
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Old 04-16-2007, 10:19 PM
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Default Re: Please interpret these labs and give opinions

Quote:
Originally Posted by vaiisking
My doctor gave me Raloxifene samples....a months supply at 60mg/day tablets. Is this similar to arimidex? Not heard anything from Raloxifene. My understanding is that it is a SERM, which is different from Arimidex, but I'm not exactly sure how.
I tried this for months because my Dr. would not give me Arimidex. Finally I got mad and asked him why don't you let me try Arimidex. He said he did not want to here from my BCBS as to why he was giving me a drug for women. Raloxifene did nothing to lower my E2 I told my Dr. to give me Arimidex that I would pay for it myself if BCBS would not pay for it. Well they did get some.

Here is a link about all of the AI's

http://www.t-nation.com/readTopic.do...geNo=-1#bottom

Raloxifene (Evista)

This drug was originally approved for the treatment and prevention of osteoporosis in postmenopausal women. Yep, yet another chick drug. Raloxifene has agonistic properties on bone. That means it acts in a similar fashion to estrogen by binding to the Beta version of the ER and inducing transcription. This is a good thing.

As a matter of fact, clomiphene and tamoxifen do this as well, but not to the same extent, it seems. What they found later about this substance was that it also has antagonistic effects on the ER alpha in humans. Thus, it could be used as an alternative to tamoxifen.

Like the other two drugs, raloxifene can also lower LDL levels because of its agonistic effects on lipid metabolism. Is it beneficial to LH and Testosterone levels? It seems as though it is, but not to a very great extent; perhaps less than that of tamoxifen. (8) So, if you’re after it for a means of preventing gyno, I’d say a dosage of 60 to 240 mg is necessary. For a possible elevation of endogenous Testosterone, higher dosages would need to be used, possibly 200 to 300 mg per day. The half life is 27.7 hours. The cost is about $2.25 to $3 per 60mg tab.
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Old 04-19-2007, 12:55 AM
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Default Re: Please interpret these labs and give opinions

Chris, my name also Chris and I felt I had better say something about your other tests.

First, your TSH looks low. Anything below 1.8 I equate with secondary hypothyroid (hypopituitary causing low thyroid). Your 1.2 is among the lowest I get to see in men. You need thyroid antibody tests and if you have other thyroid tests such as free or total T3 and or T4, go ahead and post them. Your low FSH and LH shows that you are hypopituitary as well.

Your ACTH and cortisol tests match with primary adrenal insufficiency. I look for upper 40's - lower 50's for acth in the morning and morning cortisol of upper 20's-lower 30's in men. I would like to see your serum acth redone (to make sure of what is going on) at the same time as an acth stim test. Because of your other tests showing hypopit, I would expect your acth to be low (below 30). Serum acth and acth stim together are what I really use in determining if primary or secondary AI.

Chris - Owner of Hypopituitary Support Group
http://health.groups.yahoo.com/group...itary_Support/
and
Hypopituitary Support Supplement site
http://www.geocities.com/chrisgj@sbc...upplement_STTM

I also help moderate these health forums

Northwest Pituitary
http://health.groups.yahoo.com/group...est_pituitary/

Addison's Disease
http://groups.msn.com/AddisonsDisease/general.msnw

Natural Thyroid Hormones ADRENALS
http://health.groups.yahoo.com/group...monesADRENALS/

Stop! The Thyroid Madness!! forums
http://www.stopthethyroidmadness.com...nity/index.php

also see
Stop! The Thyroid Madness!! informational site
http://www.stopthethyroidmadness.com/
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Old 04-19-2007, 03:20 PM
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Default Re: Please interpret these labs and give opinions

Chris,

My last tests that had those were:

Free T4 1.22 (0.71-1.85)
Total T3 1.4 (0.6-2.2)

That is all I could find.
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Old 04-19-2007, 03:38 PM
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Default Re: Please interpret these labs and give opinions

Quote:
Originally Posted by vaiisking
These labs are my most recent and are what I typically show without any form of treatment whatsoever. The most dominant things I am trying to fix are in order of importance:

Depression
Insomnia
Energy
Motivation
Memory
Erections

I also have an erratic heartbeat which feels like I have been scared and then it slows down..and does that cycle over and over all day long. Usually twice within each minute. Bloodwork is as follows:

Labs done 2 weeks ago

E2 51 (2-50) (high flag)
TSH 1.471 (0.350-5.500)
FSH 1.3 (1-12)
LH 4.1 (2-12)
Prolactin 6.2 (3-20)
Free Testosterone 130 (47-244)
%Free Testosterone 3.2 (1.6-2.9) (high flag)
Testosterone 412 (280-1070)
SHBG 12 (13-71) (low flag)
Dihydrotestosterone 413.9 (155-553)

Also, my most recent adrenal labs showed:

ACTH 61 (4-35) (high flag)
Cortisol 17 (3-17) (high flag)
TSH 1.243 (0.350-5.500)

Thyroids usually look mid range

Any input is appreciated

God Bless,
Chris
My interpretation (I'm not a healthcare professional), you are hypogonadal due to excessive estrogen, probably too much aromatization of T to E2. You are also way stressed out. Are you a coffee or caffeinated soft drink drinker?
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adrenal insufficiency , arimidex , clomiphene , cortisol , cycle , doctor , erection , estrogen , gyno , health , hypopituitary , serm , shbg , tamoxifen , testosterone

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