Post Orgasmic Illness Syndrome (POIS)

[DanielS3368]

Hello,

Does anyone know if POIS is linked too imbalanced hormone levels and neurotransmitters?

More can be read about POIS here :
Post Orgasmic Illness Syndrome (POIS) - Naked Scientists Discussion Forum

Symptoms are high intense brain fog, headaches/migraines, memory problems, impaired thinking, flu and fever like symptoms, sore joints/muscles, fatigue/exhaustion,
anxiety, tension, sensitivty too light and many more.

These symptoms can last from 1 - 7 days after an ejaculation from either
Sex or Masturbation. Females have also reported these.

Does anyone know any good practioners that could help me and many others with this rare but serious illness?

I do have high Pro, Estrone levels, low cort and dhea but a few other people have good healthy hormone levels yet suffer from POIS too,

I notice that the following hours after ejaculation blood pressure increases for 12-24 hours, shortness of breath, strong anxiety issues, face, neck and shoulder cramp also.

Could this be Excessive dopamine-norepinephrine/epinephrine conversion problem ?

Hope someone can help.

[JanSz]

Originally Posted by DanielS3368

Hello,

Does anyone know if POIS is linked too imbalanced hormone levels and neurotransmitters?

More can be read about POIS here :
Post Orgasmic Illness Syndrome (POIS) - Naked Scientists Discussion Forum

Symptoms are high intense brain fog, headaches/migraines, memory problems, impaired thinking, flu and fever like symptoms, sore joints/muscles, fatigue/exhaustion,
anxiety, tension, sensitivty too light and many more.

These symptoms can last from 1 - 7 days after an ejaculation from either
Sex or Masturbation. Females have also reported these.

Does anyone know any good practioners that could help me and many others with this rare but serious illness?

I do have high Pro, Estrone levels, low cort and dhea but a few other people have good healthy hormone levels yet suffer from POIS too,

I notice that the following hours after ejaculation blood pressure increases for 12-24 hours, shortness of breath, strong anxiety issues, face, neck and shoulder cramp also.

Could this be Excessive dopamine-norepinephrine/epinephrine conversion problem ?

Hope someone can help.

I can relate to that, but only to small extend.
Remember splitting hedache while masturbating and having dificulty to reach orgasm.
I got heavy duty vibrator, hepls a lot.
After splitting headache like that I would think twice about masturbating again.

It also happens sometimes during sex with wife.
I count this as positive experience, there would be no headache but very intense time.
Usualy I need an hour nap afterwards.

As for the reson, I think top notch, precise estrodial levels may be required for real good orgasm.
Unfortunately, when using AI, withouth Mother Nature cooperation, good E2 levels are hard to keep for extended period.
The splitting headache are probably when my testosterone was real low, mind was still asking but body was not ready sex.
.
.

[DanielS3368]

Thanks for your reply in this topic Jan

Have you ever heard of Antabuse/Disulfiram ?

"Disulfiram has been found to inhibit the enzyme dopamine-beta-hydroxylase, blocking the metabolism of dopamine into norepinephrine."

Disulfiram - Wikipedia, the free encyclopedia

I know that alot of POIS people suffer from extreme anxiety, massive raise in blood pressure, depression following ejaculation. It usually lasts 1-2 days for me but one person reported up too 30 days ... I dont know how he made it but 1 -2 days is bad enough but 30 .. that is too bad.

-------------------------------------------------------

I find this article interesting but does it make scientific sense?

This is called orgasmic stress (OS) induced by excessive conversion of dopamine-norepinephrine-epinephrine in the brain and adrenal glands under the sympathetic nervous function for you to achieve orgasm.
Action of Norepinephrine and Epinephrine on the sympathetic alpha receptor causes constriction of blood vessels upon orgasm. Excessive norepinephrine and epinephrine (excessive stress and anxiety) will eliminate the relaxation hormone prostaglandin E-1, resulting in tension in the rear brain, neck and shoulders where the norepinephrine and epinephrine neurons are very dense. Neck and shoulders have the densest neuro-hormone epinephrine and norepinephrine receptors in the body, followed by the urogenital areas (uterus, ovaries, vagina, clitoris, penis, testicles, and prostate), digestive tract and head skin. That is why stress, anxiety and panic can cause neck and shoulder pains and face cramp, urinary incontinence, infertility, prostate/uterine/ovarian tumors/cancers, prostate enlargement, erectile dysfunction (impotence and frigidity), digestive dysfunction, stomach cramps, and even hair loss(yes! Stress causes hair loss!). Excessive orgasm can produce Orgasmic Stress, resulting in these problems too. If you have a good blood circulation, excessive neurohormones Norepinephrine and Epinephrine can be dispersed out of the local tissues, then metabolized by the liver and expelled by the kidneys to the bladder. The un-metabolized neurohormones can also stimulate the bladder and urethral sympathetic nerves.
A low level of DHEA and androstenedione / estrogen will also cause excessive sympathetic nervous functions. Nausea is due to excessive epinephrine (sympathetic nervous functions) in the digestive systems - digestive stress.
Your body's responses to orgasmic stress out are the same as your work stress out. The difference is that the orgasmic stress occurs instantaneously upon orgasm and during sexual tension (extreme arousal), but both orgasmic and work stresses can last very long. To solve the orgasmic headache and nausea Orgasmic Stress), you have to
1. reduce the dopamine-norepinephrine-epinephrine conversion in the brain and adrenal medulla, and the epinephrine level in the bloodstream (who can do those? 5-HTP and Kava Kava!);
2. partially block the sympathetic alpha receptors;
3. increase the DHEA/androstenedione (for balancing testosterone and estrogen!) levels;
4. increase the acetylcholine and serotonin levels to modulate the sympathetic function for orgasm - de-stress the body for orgasm;
5. partially inhibit the acetylcholine re-uptaking in the synapses and power the parasympathetic nervous functions to balance the sympathetic functions that induce stress against the cardiovascular, digestive, liver, kidney and adrenal functions;
6. increase the prostaglandin E-1 (PGE-1) production in the local tissues by increasing the DHEA, acetylcholine (and its neurochemicals), and androstenedione levels;
7. Improve the local blood circulation by massage to quickly remove epinephrine and norepinephrine from the local tissues and to quickly replenish the local tissues with the nutrients, oxygen, DHEA/androstenedione and neurochemicals for the synthesis of PGE-1. Heating the local tissues can also promote the PGE-1 production to release the pulling or constriction pain. Massaging and heating on the neck and shoulders can extensively affect the PGE-1 concentration in the brain stem.
Note that Massaging and Heating the low abdomen, low back and tail bone can do the same effects on the PGE-1 production for release of the PMS or orgasmic/post-orgasmic pains or cramps in the low abdomen, low back/tailbone, and pelvic floor

[Gator8]

Originally Posted by JanSz

I can relate to that, but only to small extend.
Remember splitting hedache .

It also happens sometimes during sex with wife.
.
.

I used to get the same thing when younger and wife was hot. It never disuaded me though. Fortunately, the head ache didn't last long. It's sort of like alcohol. The last hangover consequence is recalled only long enough to abstain for a short time.

[demografx]

Originally Posted by DanielS3368

Hello,

Does anyone know if POIS is linked too imbalanced hormone levels and neurotransmitters?

More can be read about POIS here :
Post Orgasmic Illness Syndrome (POIS) - Naked Scientists Discussion Forum

Symptoms are high intense brain fog, headaches/migraines, memory problems, impaired thinking, flu and fever like symptoms, sore joints/muscles, fatigue/exhaustion,
anxiety, tension, sensitivty too light and many more.

These symptoms can last from 1 - 7 days after an ejaculation from either
Sex or Masturbation. Females have also reported these.

Does anyone know any good practioners that could help me and many others with this rare but serious illness?

I do have high Pro, Estrone levels, low cort and dhea but a few other people have good healthy hormone levels yet suffer from POIS too,

I notice that the following hours after ejaculation blood pressure increases for 12-24 hours, shortness of breath, strong anxiety issues, face, neck and shoulder cramp also.

Could this be Excessive dopamine-norepinephrine/epinephrine conversion problem ?

Hope someone can help.

Hi. I'm the moderator of the POIS Forum at The Naked Scientists. We're finally making some inroads into effective treatment. Here is a link to the latest posts:
Post Orgasmic Illness Syndrome (POIS) - Naked Scientists Discussion Forum

Look forward to seeing you!