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Men's Health Forum: This is a discussion on Pregnenolone within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; For the past 2 days I have tried 10mg of oral pregnenolone in the morning. The results have been really, ...

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Old 10-16-2006, 03:56 PM
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Default Pregnenolone

For the past 2 days I have tried 10mg of oral pregnenolone in the morning. The results have been really, really good. I have Adrenal Fatigue and take 5mg hydrocortisone in the morning and 25mg DHEA. I was pondering at one time whether it would be better to take pregnenolone which converts into all the Adrenal hormones (Cortisol, DHEA, Aldosterone, Progesterone, Testosterone, Estrogen), or to take the hormones individually because one does not know what pregnenolone is going to convert to, and one relies on the body's wisdom to convert pregnenolone to what it needs. Taking the pregnenolone the past couple days is making me think that it is the better route. I have experienced an even better "feeling of well being" than from using HCG.

Most of the literature discusses the use of oral pregnenolone. There is also no info about how long a single dose will be effective for. I noticed that pregnenolone is also available in a cream which delivers 15mg of pregnenolone, which I believe would be equal to about a 50mg oral dose, which I think may be too much.

Does anyone have any info on oral versus transdermal?
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Old 10-16-2006, 04:08 PM
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Default Re: Pregnenolone

http://www.vitaminusa.com/prbocr2ozbyl.html
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Old 10-16-2006, 04:56 PM
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Default Re: Pregnenolone

You might also consider sublingual drops as a more efficient delivery method.
You can titrate the topical cream dose by how you feel. - Use a1/4 tsp instead of a full pump etc.
The "essential oils" in this product could be problematic if they are lavender or tea tree, both possibly estrogenic.
10-20 mg is a good starting dose orally and give it a week or two to equilibrate in your system.
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Old 10-16-2006, 05:31 PM
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Default Re: Pregnenolone

Quote:
Originally Posted by 1cc
For the past 2 days I have tried 10mg of oral pregnenolone in the morning. The results have been really, really good. I have Adrenal Fatigue and take 5mg hydrocortisone in the morning and 25mg DHEA. I was pondering at one time whether it would be better to take pregnenolone which converts into all the Adrenal hormones (Cortisol, DHEA, Aldosterone, Progesterone, Testosterone, Estrogen), or to take the hormones individually because one does not know what pregnenolone is going to convert to, and one relies on the body's wisdom to convert pregnenolone to what it needs. Taking the pregnenolone the past couple days is making me think that it is the better route. I have experienced an even better "feeling of well being" than from using HCG.

Most of the literature discusses the use of oral pregnenolone. There is also no info about how long a single dose will be effective for. I noticed that pregnenolone is also available in a cream which delivers 15mg of pregnenolone, which I believe would be equal to about a 50mg oral dose, which I think may be too much.

Does anyone have any info on oral versus transdermal?
I could sware Dr. John said he has all his men on this now. I was going to try it but felt doing Isocort and HCG it would turn to E2. There is time release form of it.
http://search.store.yahoo.com/cgi-bi...lone+&x=21&y=8
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Old 10-16-2006, 05:40 PM
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Default Re: Pregnenolone

Quote:
Originally Posted by pmgamer18
I could sware Dr. John said he has all his men on this now. I was going to try it but felt doing Isocort and HCG it would turn to E2. There is time release form of it.
http://search.store.yahoo.com/cgi-bi...lone+&x=21&y=8
Here is a cut and paste on what Dr. John said.
I quit running pregnenolone assays--they are ALWAYS low. Dr. Rothenberg made this same comment in one of his lectures.

I use a trandermal cream whihc Signature compounds for us.

I now want all of my guys on TRT to take it, along with DHEA, to help rebalance the pathways.

Pregenenolone is lowered in TRT because the P450scc enzyme (which converts CHOL into pregnenolone) is reduced in activity by lowered gonadotropins, as it is by ACTH. This is also why I always use HCG in every TRT patient.
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Old 10-16-2006, 05:47 PM
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Default Re: Pregnenolone

Quote:
Originally Posted by Naturdoc
10-20 mg is a good starting dose orally and give it a week or two to equilibrate in your system.
How long does the effect of pregnenolone last when taking a single morning oral dose? Is it necessary to take more than one dose per day in your experience? The cream has the effect of a prolonged release, although I'm not sure if this is necessary.
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Old 10-16-2006, 05:50 PM
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Default Re: Pregnenolone

Quote:
Originally Posted by pmgamer18
I could sware Dr. John said he has all his men on this now. I was going to try it but felt doing Isocort and HCG it would turn to E2. There is time release form of it.
http://search.store.yahoo.com/cgi-bi...lone+&x=21&y=8
I believe Dr. John has one of his patients take 60mg pregnenolone cream, which is a very high dose for a cream.

Some of what I have read has said that if you take pregnenolone and DHEA, one should reduce the DHEA by the amount of the added pregnenolone. So if one takes 50mg DHEA per day and decides to take 25mg pregnenolone, then the DHEA should be reduced to 25mg per day as well.
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Old 10-16-2006, 05:59 PM
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Default Re: Pregnenolone

Quote:
Originally Posted by 1cc
I believe Dr. John has one of his patients take 60mg pregnenolone cream, which is a very high dose for a cream.

Some of what I have read has said that if you take pregnenolone and DHEA, one should reduce the DHEA by the amount of the added pregnenolone. So if one takes 50mg DHEA per day and decides to take 25mg pregnenolone, then the DHEA should be reduced to 25mg per day as well.
Good point I believer Dr. Low talks about this I am going to do some searching see what I can find.
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Old 10-16-2006, 06:38 PM
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Default Re: Pregnenolone

There is some talk about Pregnenolone in this link.
http://www.totalityofbeing.com/Archi...eofaPenis.html
I said Dr. Low I ment to say Dr. John Lee.
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Old 10-16-2006, 06:43 PM
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Default Re: Pregnenolone

This has a lot in it.
http://www.tidesoflife.com/pregprodhea.htm
From this seach.
http://www.google.com/search?hl=en&l...2BPregnenolone
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