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Old 10-21-2009, 05:16 PM
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Default Propecia: estrogen and hormone balancing

I am on a needle-centric TRT regimen -- injecting 38 mg testosterone cyp. twice a week, plus 250 IU of HCG twice a week. (Gels and creams created way too much DHT regardless of formulation or skin surface size.) However, even with injections, my DHT levels were still slightly above the normal range, and I am losing my hair big time. So I decided to take 1/4 dose of propecia daily. Within two weeks, my DHT dropped from 95 to 28.

However, my estrogen (E2) level shot up to 55 picog/ml, and my PSA levels oddly went up too. Does anyone know if propecia increases E2 levels? What is the proper level of E2? And can anyone recommend a non-drug supplement that might reduce the E2?

Thanks for reading all this!
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Old 10-21-2009, 05:40 PM
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Default Re: Propecia: estrogen and hormone balancing

1/4 dose? Isn't that .25 mgs of finestaride? Thats not much. Dont get me wrong as I have heard many stories on long term ill effects from using that drug, so I would research and reconsider. Note that each different person has a different DHT threshold for each particular body area. Your body may just be bent on loosing head hair. That is the genetic side to this application. If you have a "pretty head" just go with it. But dont forget to note your prostate's reaction to DHT as well. I would get to the urologist and get a baseline PSA and digital exam so that you will know where those figures are while you are healthy. Your testosterone dose is low even for TRT. Also keep in mind that only about 70-80% of the injectible cypionate compound in testosterone. So the rest is carbon ester. Meaning that at your current weekly doseage of 76mgs, you are only actually getting 60 +/- mgs of test.

I am guessing that since both DHT and E2 are durivatives of testosterone, and now that you are converting less to DHT, the excess in thus available for Estrogen conversion. Since your body favors high DHT levels then it is probably also inclined to produce estrogens more easily, given that E2 is the natural counter for DHT. You are throwing off that balance. The best way I know of to prevent E2 conversion is Arimidex. Naturally speaking, avoiding soy products, plastics(in both cooking and botteling), and lowering your body fat content in general will help to lower E2. It would be interesting to know what your SHBG, test, free test, and E2 readings are. What is your age?? Unfortunately it sounds like you are genetically inclined to have less hair on your head (given the eyes of the beholder). I would just make sure to start tracking your prostate now. Reason being is that there is so much research right not with regard to prostate and its relation to androgens. One side states that high DHT in the prostate will give prostate cancer. Another side (the one I am going with) states that it is not the prolonged exposure to high androgens that cause cancer, but the lack of ample supply of them once you are older and production starts to slow. YOU NEED TO KNOW WHERE YOU ARE NOW!!!!! Do yourself a favor and have a full expanded male hormone panel done ASAP... As far as the HCG goes, I believe it has a stimulating effect on testosterone and thus estrogens. It is always a good idea to supp HCG while taking exogenous testosterone. Please give more info...

One further. I find it VERY interesting that your PSA levels went up with lack of DHT and increased E2. This is very supportive of that latter of the tow theories, of which I am banking my life on!! Very interesting.


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Originally Posted by drp90210 View Post
I am on a needle-centric TRT regimen -- injecting 38 mg testosterone cyp. twice a week, plus 250 IU of HCG twice a week. (Gels and creams created way too much DHT regardless of formulation or skin surface size.) However, even with injections, my DHT levels were still slightly above the normal range, and I am losing my hair big time. So I decided to take 1/4 dose of propecia daily. Within two weeks, my DHT dropped from 95 to 28.

However, my estrogen (E2) level shot up to 55 picog/ml, and my PSA levels oddly went up too. Does anyone know if propecia increases E2 levels? What is the proper level of E2? And can anyone recommend a non-drug supplement that might reduce the E2?

Thanks for reading all this!
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