shbg and free testosterone

[masterpp]

hey guys,

i was recently told that my very elevated shbg was partially the result of my high fat low carb diet.

i therefor assumed that high shbg leads to low free testosterone, and that increasing my insulin, by having some more carbs and varied foods in my diet, would lower shbg and thus free up some testosterone- which most would assume is a good thing

but then i dont understand this document

http://jcem.endojournals.org/cgi/reprint/79/4/1173.pdf

on page 1176 half way down it suggests that low shbg does not correlate with higher free t in men- i dont get it- i thought shbg was a bad thing we dont want if one has low total t and low free t

any comments please

[JanSz]

Originally Posted by masterpp

hey guys,

i was recently told that my very elevated shbg was partially the result of my high fat low carb diet.

i therefor assumed that high shbg leads to low free testosterone, and that increasing my insulin, by having some more carbs and varied foods in my diet, would lower shbg and thus free up some testosterone- which most would assume is a good thing

but then i dont understand this document

http://jcem.endojournals.org/cgi/reprint/79/4/1173.pdf

on page 1176 half way down it suggests that low shbg does not correlate with higher free t in men- i dont get it- i thought shbg was a bad thing we dont want if one has low total t and low free t

any comments please

There are relationships betweel everything with everything.

Some of them are strong, some weak some not worth mentioning.

When FreeTestosterone is concerned, as far as I know there are two strongly related items

Total Testosterone and SHBG
there is third one, Albumin, already considered weak.

All the rest go behind Albumin.
Not sure how E2 would fare, when it is very high it increases SHBG (and lowers freeT).

It would be real nice someone could make a list of the 200-300 indicators that we usually observe and figure our corelation factors between each pair.
==============================================
Wonder how they were figuring out the Freet and FreeE2.
This is "old" 1994 research.
Since then I know of two items that may have influenced their conclussions.

1.inaccuracy of FreeT analysis

2. discovered "duality" of SHBG that further dilutes accuracy of FreeT analysis or calculations.

-----------http://www.atypon-link.com/WDG/doi/pdf/10.1515/JLM.2006.050