SWALE and HCG

[James23]

I hear SWALE is asking all patients with SHBG problems to contact his office regarding some "new" protocols. Does anyone have any information about what he is up to?

[marianco]

Originally Posted by James23

I hear SWALE is asking all patients with SHBG problems to contact his office regarding some "new" protocols. Does anyone have any information about what he is up to?

Low SHBG is most associated with high insulin levels due to insulin resistance or diabetes - which is associated with Metabolic Syndrome.

SHBG is raised by thyroid, estrogen, and progesterone.
SHBG is lowered by insulin, testosterone, DHT, growth hormone, DHEA, and other androgens.

Supraphysiologic doses of testosterone or other androgens can drive SHBG lower.

I don't have any information on what Dr. Crisler is up to.

However, perhaps it may be related to the above information.

For example, if one has insulin resistance/diabetes, it may be treated with substances/medications such as Actos or Avandia to improve insulin sensitivity. It may be important to aggressively treat insulin resistance since leaving it untreated results in a much higher risk of heart disease, hypogonadism, obesity, stroke, mood disorder, dementia, among many other illnesses.

[James23]

Thanks for the information, marianco!

Strangely, though, I acually have mild postasbsortavie (fasting) hypoglycemia (which is the opposite of diabetes, right?)

Better stated, I symptoms of low blood sugar if a meal is missed. I will become suddenly extremely tired, pass out, and awaken an hour or so later very confused, with a headache, feeling very sick. If I don't force myself to stand up (at which point, I am shaky and weak) I have the overwelming urge to just lay down and pass out again. Somtimes, I will wake up this way in a sweat. I have a glucose meter, and discovered that my levels do not drop below 70 mg/ml during the "spells," they just drop very close to 70, at which point my body feels like absolute hell. Since they aren't below 70, I can't get treated for hypoglycemia. Another case of doctors using those global averages as doctrine for individuals.