Terresw question about Clomid and BBC3 PM

[BBC3]

I have posted here as too large for PM and I am not going to waste all that good typing.

To my knowledge, clomid will stimulate pituitary activity on an "all-around" type basis. However, I am not a physician (not that most of those assholes even have a clue about this stuff!). In the TRT section I have heard some of the more knowledgeable speak about "doing a Clomid Challenge". I believe that by the application of Clomid, you are attempting to rule out primary hypogonadism. Meaning, and I think that primary is defined as a failure of the testicles, that if you add Clomid and get a response then you know that they are working and the problem has to be higher up (pituitary/brain/etc..) So with that said, if my assumtions are correct, you should be able to feed yourself some clomid and the testicles should act as close to normal expectations as possible. Then you have proven that they are working Ok. A few things to keep in mind. I have read that the leydig portion of the testicle is a very small area in relation to the actual mass and size of them. This would mean that regardless of the size and physical condition, the testicles could have suffered damage, be disfuntional in leydig or other areas of function, not be working correctly. Clomid challenge should prove or disprove this possibility. Also I understand that Clomid should be dosed anywhere from 50, 100, or 150mgs/day. They say that at 150mgs, the side effects can be difficult to deal with. i believe "they: are referring mostly to the emotional aspect of the drug. Drugs like CLomid and Novadex have some slight inheirent risk associated with using them, just as any other pharmaceutical medication does. With this said, if you are going to experiement with Clomid (with or without an asshole physician), you shold be careful to pay attention to your body. I also understand that use of Clomid can contribute to some the blood clotting more easily. I think this is more common in long term use.

In short conclusion. I think that in your situation I would certainly try clomid to see how I reacted. They say that you should have a good response from it within 10 days. So I would assume that you should definity feel the physical results with a months use. Personally I would attemp ramp up to 150mgs over first 3 days. Spend a full 7 days at 150mgs. Then 10-12 days at 100mgs. And finally 10 more days at 50mgs. I dont think that I would ever consider clomid as A long term solution to secondary hypogonadism due to the negatives with long term exposure. I am not sure of your stats at this time, but if low on testosterone, I would prefer 150mgs cypionate/week combined with HCG and HMG therapy to stimulate and preserve the boys.

Further, if it does turn out that you are having issues other than a primary failure of the testicles, then you should also first thoroughly explore all possibilities. Meaning that if you are having a signalling issue from the brain, regardless of whether the cause be the pituitary, (or higher) the hypothalmus, ( or even higher) some sort of generalized problem with the brain, thenj you need to make sure you are not having problems elsewhere. I understand that there is a lot of research indicating that if there is a problem with the Thyroid, then it can cause these hormonal problems as it may very well supercede the pituitary in this chicken or egg argument. I have also read that the pancrease can have an impact causing these type of testosterone related hormonal issues. Personally I am thinking that insulin activity is a much less likely suspect in this situation, as compared to a malfunction of the Thyroid. So I would look there first, and prior to Clomid use.

Other, Please keep in mind that if you post these questions and issues just as you have pm'd me, I will still repsond the same, and others can benefit from the information as well. Also as this keeps all your information regarding the matter in one place where I could check the thread to see if you have posted Thyroid, etc, and not remain ignorant as I am trying to answer. If you feel like you are not getting a response from the party you are interested in hearing from, such as me in this case, then PM me if I have missed it or have been away for a while, and I'll get the email notifying me to go have a look and help. Just makes it easier mostly so I can see all the info you have posted.

MOST IMPORTANTLY!!! Take everyone around here with a LARGE grain of salt. Including me!! You can get bad information that may sound right in a hurry. This is another good reason to keep things on a public thread as guys out there can catch me if I am giving bed advice and help to prove it to you and prove to you the more correct direction. If you would like you could even start a thread and copy and paste the body of this PM and that way you could get even more feedback and even a critique of the info I have provided. If not let me know how things go either way.

Thanks for your regard for my thought.

Originally Posted by terresw

Is it able to raise lh and fsh vlaues in pretty much everyone? Reason being is I am thinking of wswiutching to trt just using clomid. My nuts work, but my pituitary was the issue.

[terresw]

That is an excellent and insightful answer BBC.

Originally Posted by BBC3

I have posted here as too large for PM and I am not going to waste all that good typing.

To my knowledge, clomid will stimulate pituitary activity on an "all-around" type basis. However, I am not a physician (not that most of those assholes even have a clue about this stuff!). In the TRT section I have heard some of the more knowledgeable speak about "doing a Clomid Challenge". I believe that by the application of Clomid, you are attempting to rule out primary hypogonadism. Meaning, and I think that primary is defined as a failure of the testicles, that if you add Clomid and get a response then you know that they are working and the problem has to be higher up (pituitary/brain/etc..) So with that said, if my assumtions are correct, you should be able to feed yourself some clomid and the testicles should act as close to normal expectations as possible. Then you have proven that they are working Ok. A few things to keep in mind. I have read that the leydig portion of the testicle is a very small area in relation to the actual mass and size of them. This would mean that regardless of the size and physical condition, the testicles could have suffered damage, be disfuntional in leydig or other areas of function, not be working correctly. Clomid challenge should prove or disprove this possibility. Also I understand that Clomid should be dosed anywhere from 50, 100, or 150mgs/day. They say that at 150mgs, the side effects can be difficult to deal with. i believe "they: are referring mostly to the emotional aspect of the drug. Drugs like CLomid and Novadex have some slight inheirent risk associated with using them, just as any other pharmaceutical medication does. With this said, if you are going to experiement with Clomid (with or without an asshole physician), you shold be careful to pay attention to your body. I also understand that use of Clomid can contribute to some the blood clotting more easily. I think this is more common in long term use.

In short conclusion. I think that in your situation I would certainly try clomid to see how I reacted. They say that you should have a good response from it within 10 days. So I would assume that you should definity feel the physical results with a months use. Personally I would attemp ramp up to 150mgs over first 3 days. Spend a full 7 days at 150mgs. Then 10-12 days at 100mgs. And finally 10 more days at 50mgs. I dont think that I would ever consider clomid as A long term solution to secondary hypogonadism due to the negatives with long term exposure. I am not sure of your stats at this time, but if low on testosterone, I would prefer 150mgs cypionate/week combined with HCG and HMG therapy to stimulate and preserve the boys.

Further, if it does turn out that you are having issues other than a primary failure of the testicles, then you should also first thoroughly explore all possibilities. Meaning that if you are having a signalling issue from the brain, regardless of whether the cause be the pituitary, (or higher) the hypothalmus, ( or even higher) some sort of generalized problem with the brain, thenj you need to make sure you are not having problems elsewhere. I understand that there is a lot of research indicating that if there is a problem with the Thyroid, then it can cause these hormonal problems as it may very well supercede the pituitary in this chicken or egg argument. I have also read that the pancrease can have an impact causing these type of testosterone related hormonal issues. Personally I am thinking that insulin activity is a much less likely suspect in this situation, as compared to a malfunction of the Thyroid. So I would look there first, and prior to Clomid use.

Other, Please keep in mind that if you post these questions and issues just as you have pm'd me, I will still repsond the same, and others can benefit from the information as well. Also as this keeps all your information regarding the matter in one place where I could check the thread to see if you have posted Thyroid, etc, and not remain ignorant as I am trying to answer. If you feel like you are not getting a response from the party you are interested in hearing from, such as me in this case, then PM me if I have missed it or have been away for a while, and I'll get the email notifying me to go have a look and help. Just makes it easier mostly so I can see all the info you have posted.

MOST IMPORTANTLY!!! Take everyone around here with a LARGE grain of salt. Including me!! You can get bad information that may sound right in a hurry. This is another good reason to keep things on a public thread as guys out there can catch me if I am giving bed advice and help to prove it to you and prove to you the more correct direction. If you would like you could even start a thread and copy and paste the body of this PM and that way you could get even more feedback and even a critique of the info I have provided. If not let me know how things go either way.

Thanks for your regard for my thought.