Wilson's Syndrome, sounds like me, please help me

[Warrior21]

Okay if you guys are familiar with Wilson's Syndrome, it really sounds like what is happening to me. Even when I take massive amounts of straight T3, I see no effects from it. I am hypothyroid. I'm 99% sure it is due to poor cellular utilization of the t3 hormones.
T3 and steroids have the same nuclear receptor types. This would most certainly explain why I do not respond to steroids or thyroid medication. This should be an eye-opener to others who are on HRT or thyroid medication and are not feeling better, and have already ruled out Adrenal Fatigue.
Okay next, I know I need to get the Genova ONE test done. But it will be a couple of months before I can afford that. I know my poor cellular utilization has to due with a certrain trace element/vitamin/mineral deficiency. Problem is, I don't know what. Can some of you smarter folk get on here and maybe suggest any?
I know for one, I used to sweat copper out like crazy. I do not get any supplemental copper at all in, and for years I supplemented plenty of Zinc. I'm sure I'm copper deficient. Selenium is another, I don't recall really getting much of that. Magnesium as well, what else can you guys think of?
Do you guys know anything about cell membrane permeability? I've been researching that which is related to the Wilson's Syndrome. It makes sense, but what can I do to get those membranes a bit more permeable so that the thyroid/steroids can pass and activate receptors to do their job?

[coz]

Originally Posted by Warrior21

Okay if you guys are familiar with Wilson's Syndrome, it really sounds like what is happening to me. Even when I take massive amounts of straight T3, I see no effects from it. I am hypothyroid. I'm 99% sure it is due to poor cellular utilization of the t3 hormones.
T3 and steroids have the same nuclear receptor types. This would most certainly explain why I do not respond to steroids or thyroid medication. This should be an eye-opener to others who are on HRT or thyroid medication and are not feeling better, and have already ruled out Adrenal Fatigue.
Okay next, I know I need to get the Genova ONE test done. But it will be a couple of months before I can afford that. I know my poor cellular utilization has to due with a certrain trace element/vitamin/mineral deficiency. Problem is, I don't know what. Can some of you smarter folk get on here and maybe suggest any?
I know for one, I used to sweat copper out like crazy. I do not get any supplemental copper at all in, and for years I supplemented plenty of Zinc. I'm sure I'm copper deficient. Selenium is another, I don't recall really getting much of that. Magnesium as well, what else can you guys think of?
Do you guys know anything about cell membrane permeability? I've been researching that which is related to the Wilson's Syndrome. It makes sense, but what can I do to get those membranes a bit more permeable so that the thyroid/steroids can pass and activate receptors to do their job?

Are you saying you have taken massive doses of T3 by itself for a long period of time ? Without any T4 med at all ?? If so, doesn't sound like Wilson's Syndrome - as that is the recommended way to treat it.

http://knoxintegrativemed.com/wilson's%20syndrome.htm

[Warrior21]

No, not for long periods of time. If the hormone was going to be utilized, it would have been utilized within a matter of hours.
Wilson's studies due provide more insight to what may be going on though. It's definately a deficiency in something. But until I can afford metabolic testing, I'm just going to have to 'guess and check'. Of course, with tons of research and discussion first.

[coz]

The theory with Wilsons Syndrome - Reverse T3 syndrome, is that once you have it, your body will continue to convert T4 to RT3 while you have T4 in your body. RT3 in inactive and can fit into the T3 receptor, therefore blocking T3 from it.

So the recommended treatement is to ramp up on T3 only, until your body no longer has T4 - this takes a few weeks due to T4's long half life. You stay on T3 for about 30 days before ramping down. At which point the theory is that your body will hopefully start converting T4 to T3 correctly, and not RT3.

It's all in the link I provided..

[Warrior21]

Okay this article is directly from Wilson's homepage. There's more possibilities to Wilson's Temperature Syndrome than just RT3 dominance. In this article you will see how mineral/trace elements can effect membrane permeability.

THYROID ASSESSMENT

I'm just hoping someone can get on here and learn me on that. I'm getting myself up to date on metabolic typing, and chelation as we speak. I also ordered Dr.Rinds "Basic Cell Energy" by Dove Health Products. Found here: Dove Health Products Item Description

I think the supplement is going to help too.

[coz]

That link points to a webpage by Lawrence Wilson, MD. He is not the Dr Wilson who the Wilson Syndrome is named after - that is Dr. E. Denis Wilson

Wilson's Temperature Syndrome -- Review Article
Position Statement

[Warrior21]

My mistake. Well even still, that Lawrence Wilson sounds like he really knows what he is talking about. I wish I could get a consult with him. But I bet his prices are ridiculous.