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Old 03-15-2007, 11:37 AM
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Default Would ADVAIR and/or FLONASE impact my HPTA negatively?

My GP just wrote me a script for Advair and Flonase in order to combat my allergies. Since both meds have some sort of steroidal substances, Do they have any negative impact on my HPTA? This is very important to me as I have just recovered my HPTA, been feeling pretty well, and I don't want to take anything that may set me backwards. Please let me know before I embark on these meds.
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Old 03-15-2007, 08:25 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by BigAk
My GP just wrote me a script for Advair and Flonase in order to combat my allergies. Since both meds have some sort of steroidal substances, Do they have any negative impact on my HPTA? This is very important to me as I have just recovered my HPTA, been feeling pretty well, and I don't want to take anything that may set me backwards. Please let me know before I embark on these meds.

I don't believe that inhaled steroids would have a direct effect on your HPTA. But long-term use of inhaled steroids can suppress adrenal function, and we all know that underactive adrenals can negatively effect T level.
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Old 03-15-2007, 11:27 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

The steroids in the inhalers are antihistamines and like mentioned above can cause adrenal shutdown after long term use. Here are some other sides...

* increased appetite and weight gain
* deposits of fat in chest, face, upper back, and stomach
* water and salt retention leading to swelling and edema
* high blood pressure
* diabetes
* black and blue marks
* slowed healing of wounds
* osteoporosis
* cataracts
* acne
* muscle weakness
* thinning of the skin
* increased susceptibility to infection
* stomach ulcers
* increased sweating
* mood swings
* psychological problems such as depression
* adrenal suppression and crisis
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Old 03-16-2007, 12:55 AM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by advanced-stealth
The steroids in the inhalers are antihistamines and like mentioned above can cause adrenal shutdown after long term use. Here are some other sides...

* increased appetite and weight gain
* deposits of fat in chest, face, upper back, and stomach
* water and salt retention leading to swelling and edema
* high blood pressure
* diabetes
* black and blue marks
* slowed healing of wounds
* osteoporosis
* cataracts
* acne
* muscle weakness
* thinning of the skin
* increased susceptibility to infection
* stomach ulcers
* increased sweating
* mood swings
* psychological problems such as depression
* adrenal suppression and crisis
They are NOT antihistamines, they are corticosteroids/ bronchodialtor. Side effects are dose dependant. Systemic effects are usually low. I was used to use lots of inhalers/nebulizers. Asthma is very controlled with singulair. I only take the blue one when I am around heavy allergens/irritants (cats/dogs/smoke)
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Old 03-16-2007, 02:18 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by advanced-stealth
The steroids in the inhalers are antihistamines and like mentioned above can cause adrenal shutdown after long term use. Here are some other sides...

* increased appetite and weight gain
* deposits of fat in chest, face, upper back, and stomach
* water and salt retention leading to swelling and edema
* high blood pressure
* diabetes
* black and blue marks
* slowed healing of wounds
* osteoporosis
* cataracts
* acne
* muscle weakness
* thinning of the skin
* increased susceptibility to infection
* stomach ulcers
* increased sweating
* mood swings
* psychological problems such as depression
* adrenal suppression and crisis

Corticosteroids are not antihistamines. There use and their effects overlap some, but they are two different classes of substance.
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Old 03-16-2007, 02:24 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Most authorities and studies indicqte that there is little long term effect on the HPTA. Ive seen one or two to the contrary. Ive been on them for 3 yrs. my skin is noticibly thinner, but there could be other factors involved. Its the oral (prednisone ) that will fuck you up.
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Old 03-16-2007, 02:35 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by zkt
Most authorities and studies indicqte that there is little long term effect on the HPTA. Ive seen one or two to the contrary. Ive been on them for 3 yrs. my skin is noticibly thinner, but there could be other factors involved. Its the oral (prednisone ) that will fuck you up.

But a prednisone blast can be a godsend when nothing else works.
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Old 03-16-2007, 02:38 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by keaster
They are NOT antihistamines, they are corticosteroids/ bronchodialtor. Side effects are dose dependant. Systemic effects are usually low. I was used to use lots of inhalers/nebulizers. Asthma is very controlled with singulair. I only take the blue one when I am around heavy allergens/irritants (cats/dogs/smoke)

That's great that the singulair works so well for you. It is very expensive and a disappointment for most adults - although kids tend to get a good result from it.
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Old 03-16-2007, 03:07 PM
zkt zkt is offline
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

"But a prednisone blast can be a godsend when nothing else works."
No doubt about that or sure. I was meaning the long term effects. Good to note thge distinguition
INow that you mention Singulair, I take it and have ben wondering how much good it is relly doing. Might stop it for a while and see what happens.
". It is very expensive" - you know who to thank for that dont you? . Its a good thing I went to Nam instead of Canada. LOL (cant beat the VA prices)
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Old 03-16-2007, 03:23 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by advanced-stealth
Here are some other sides...

* increased appetite and weight gain
* deposits of fat in chest, face, upper back, and stomach
* water and salt retention leading to swelling and edema
* high blood pressure
* diabetes
* black and blue marks
* slowed healing of wounds
* osteoporosis
* cataracts
* acne
* muscle weakness
* thinning of the skin
* increased susceptibility to infection
* stomach ulcers
* increased sweating
* mood swings
* psychological problems such as depression
* adrenal suppression and crisis
Hmmmm....... My chronic cough is sounding better and better lemme tell you... LOL
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Old 03-16-2007, 03:23 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

So what's the consensus?? Shall I use 'em.. or lose 'em??
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Old 03-16-2007, 03:59 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Depends on how much the breathing problem fucks you up. Try em and see if its better. The long term effects arent much when compared to not being able to do what you want. to do. You didnt say how bad is the problem. So how bad ?
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Old 03-16-2007, 04:24 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Quote:
Originally Posted by BigAk
So what's the consensus?? Shall I use 'em.. or lose 'em??

You said this was for allergies, meaning use will probably be occasional or seasonal. To me, that would be OK. This stuff has a way of turning into long-term, regular use, though. So be mindful of that. If the symptoms are tolerable, as it seems they might be, why complicate the picture?


Nasal-crom is a pretty good non-steroid nasal spray. The downside is that you need to use more often than a corticosteroid like flonase.
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Old 03-16-2007, 04:30 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

My issue is not that severe.... I just can't seem to shake this persistent cough that sometimes it's pretty bad.... It's as if something is not getting cleared in my lungs... I've been like this since Mid December. I don't predict this will be a life long issue as I'm 40 now and never experienced it. Besides, allergies here in the south east are pretty bad due to the blooming trees and pollen etc... so this could be seasonal.. I may try the stuff for a little while and see.. Once I start experiencing bad sides, I'll quit.
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Old 03-16-2007, 04:49 PM
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Default Re: Would ADVAIR and/or FLONASE impact my HPTA negatively?

Sounds like chronic bronchitus to me. Which is probably not a revelation Do you smoke ? Funny if its allergen induced it stared when the pollens are a low. But heat ducts are full of stuff. Is the cough productive or the dry hacking kind?
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