I've been reading a lot lately on PCT and came across an article talking about long term use of
clomid and nolva. I found it pretty interesting to read that nolva and
clomid actually have pretty horribly bad side effects after a long term use and there is a safer and more effective way to do PCT with Dermacrin Sustain. Now I really don't know too much about it but I read that it is a lot safer and effecitve. The down side to it is that it is 90 times less effective than nolva and 30 times less effective than clomid because of its low binding effect. But I would think that if somebody were to be taking Adex for their PCT and using the dermacrine sustain that it would be far more effective than just the nolva or clomid run by themselves. Here is a couple paragraphs that I was reading from an article I saw.
"Another SERM that may be useful for post cycle therapy is resveratrol.87,88 Resveratrol is a natural polyphenol extracted from grape skin, that has recently been under heavy research for its cancer fighting effects in the breast, prostate and liver.63-69 Contrary to Nolva or Clomid, resveratrol appears to actually have beneficial effects on the liver,70 as well as having multiple benefits on cardiovascular health by limiting LDL oxidation and improving endothelial function.71-73 Improved blood vessel function may be a mechanism by which resveratrol improves erectile function in many men. Research also suggests that resveratrol may actually extend life, by reducing oxidative stress on organs such as the heart,77 and preventing the metabolic syndrome by fighting insulin resistence.79,80 It’s becoming well known that insulin resistance is a leading cause of low
testosterone.82 More specifically, improving insulin sensitivity will increase your leydig cell sensitivity, and therefore increase the testes response to LH.81
It should be pointed out that resveratrol may not be the best choice to combating emergency gyno, due to its lower binding affinity to the human ER of about 90x less than tamoxifen, and about 30x less than clomiphene.75,76 However, considering that resveratrol is a pure estrogen antagonist at the pituitary,89 while Clomid has mixed agonist/antagonistic effects,90-94 resveratrol could be a suitable substitute for PCT. Aside from acting as a SERM, resveratrol can also help control estrogen by actually limiting aromatase enzyme production.82 Based on the research, it appears that at least 100mg/day would needed to increase LH, FSH and
testosterone production.84 This is comparable dose of resveratrol found in an advanced topical based product, Dermacrine Sustain (found here -
http://www.**************************). "(this article was off of meso and written by Eric Potratz)
I was just wondering if anybody had anymore thoughts on this? And would it be mroe effective to run adex and dermacrin instead of nolva or clomid for PCT?
Dermacrin Sustain for PCT 
Linear Mode
