Steroid Forum: This is a discussion on How to not fuck up DNP within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; Originally Posted by ziggy
Hey bro I appreciate your evidence for DNP however I was a little concerned by the ...
Hey bro I appreciate your evidence for DNP however I was a little concerned by the spec sheet for the antibody for DNP as an antidote. Antibodies aren't antidotes; they do however have an integral part in the adaptive immune response. This is done by immature B-cells in the bone marrow being selected for affinity for an antigen. Once selection has taken place the B-cell becomes a plasma cell secreting antibodies specific for the antigen. The way the antibody can kill/remove the antigen is to be recognized by a T-helper cell which is MHC-restricted. Then programmed death (apotosis) can occur. The antibody on the spec sheet is made from a host other than human which means that if you introduced this Ig into a human the host will recognize this as foreign and build an immune response to it. Also if the foreign Ig is able to bind DNP in the host it would not allow program cell death because the T-helper cell has to be MHC restricted meaning that it will not recognize anitigen that is in the binding pocket of the major histocompatibility complex. That's all I have to say about that but I would like to try some DNP, maybe pm me so that I can get some, Thanks
Wow....someone likes to use their science book to write. I'll try and keep my explanation down a little closer to those of us that read plain old English.
Why does DNP work, it basically causes the KATP gateway to stay open, allowing a inefficiency in the formation of ATP (energy packets) and the need for the body to use more fat to produce the same amount of energy. The Antidote (ne: antibody), is actually a proteolytic (sorry...big word) that allows the KATP gateway to be shut....thereby causing DNP to have less effect.
I like your thoughts Ziggy, but in this case the agent acts a little different than through the binding of antibody to the DNP molecule. Cellular death in this case does not result from a suppression of the immune system (re: T-Cell activity). The antibody is not designed to help the immune system, so therefore there is no need for it to be MHC restricted, and at the required doseage and time frame the half-life is such that the immune system should not immediately respond in a fashion which would reduce it's effectiveness.
Bottom line: Keep with the required doses and the last two posts become totally irrelevant unless you are an ER doc who is about to $h!t his pants because he has an idiot laying on a table in a pool of sweat.
As far as "giving it a try", please don't until you read much more research about the drug and the action that it has on a cellular level.
Now after that last post I have questions.... Is it safe or not? Can see the safe dose recommendations and feel that only an idiot would test the limits of those.
Kemo, what other research would you recommend.
I am 38, around 200lbs and play competitive racquetball. I need to cut about 15 pounds. Racquetball has aerobic and anaerobic components. I want to drop some excess weight and then get stronger. Any thoughts?
As far as DNP being safe or not, it's more or less like asking if steroids, insulin, or diuretics are safe or not. Yes and no. If you use them responsibly and follow the rules, you'll be fine. If you fuck around and do stupid shit like use rec drugs or take too much, then you may have a problem. It's clearly explained at the beginning of the post how much to use and for how long, but to recap you take 200mg the first few days to see how you react, and then you can bump it up to 400mg for about a week at most. After that the fat-loss effect becomes greatly diminished, but you can cycle it like gear (time on=time off) until you get where you want to go.
Obviously I have a vested interest in saying it's safer than most people think, but I firmly believe insulin and diuretics are FAR more dangerous than DNP, and look at how many people use those. Look at how many pros have DIED from both of those items, but they don't have the same fear factor that DNP seems too. A healthy respect for DNP is good though, because the only time a drug becomes dangerous is when you lose your fear of it and become careless.
Regards,
-H-
heretic-what are your thoughts on a week on, week off cycling of dnp? or would 2 weeks on, 2 weeks off be more effective? running a 4day warm up of 200, then 2 days 400, then 600 to see how my tolerance is at that doseage. then if i take a week off would i have to run the same steps? or can i start right at 400? I will most likely use 400 for a while if its effective enough.
Anyone feel free to leave their opinion on this cycle. thank you.
One week would be better than two, like I said after about 9 days it kind of loses it's kick, plus you'll be miserable and want to stop anyway. I'd then take at least a week off, maybe two, to let the water bloat drain out and allow for glycogen supercompensation (anabolic rebound). But damn, when that water comes off and you see the results it's something else.
Regards,
-H-
PL posted: "but another famous quote is, 'DNP will raise your body temp high enough to kill you!' This also proves that he has never done it because as you will find, your body temp only goes up about one degree. Ok, enough about the fake guru."
DNP will kill a person if doses are too high, to say differently is not only false but also dangerous to people that read that information. This isnt specifically against PL, but anyone who says that DNP cant be lethal. Whether death occurs from a rise in oral temperature or through some other factor isnt important. Id have to look up and see what the reasoning is.
I'll try and keep my explanation down a little closer to those of us that read plain old English.
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