How to not fuck up DNP

[bigntasty21]

Originally Posted by krayg

has anybody had real good results with this stuff? I want to do it but can't afford to be a worthless slug at work.

hard to say for results since this is my 4th day...but i seem a little leaner...although it hasnt really kicked in yet...either that or i can handle the sides well =). Woke up the last 2 mornings with a wet back...didnt like that too much..otherwise no sweating...just overal warmness...started taking 400mgs yesterday...taking the same today and going to stick with that since its my first dnp cycle..will update in a day or 2 =)

[bigntasty21]

[okay...end of day 5...not much difference but overall pretty warm but definately nothing i cant handle. been on 400mgs for 3 days now so im deciding to bump it up to 600mgs...and i dont think ill go above this dose..since its my first cycle...wish me luck =)

[BEEFarmer]

BACKGROUND-

"Body weight is regulated by an endogenous body mechanism. Physiological and neurological properties establish and maintain a given weight. Briefly stated, glycerol which is released during hydrolysis of triglycerides and adipose tissue is widely believed to regulate caloric intake and metabolism. Others have postulated that caloric intake is affected by both body temperature and environmental temperature. In addition, cell size and number affect energy regulation. Weight gain cannot be predicted solely on the amount of calories ingested.

In normal persons, thermogenesis is an adaptive mechanism which increases the metabolic rate after overeating. While a normal person will experience an increase in thermogenesis following increased caloric intake, the obese either has a substantially decreased thermogenic mechanism or lacks this particular mechanism entirely.

The use of dinitrophenol to treat obesity is known. Dinitrophenol is known to elevate the body temperature and produces a marked increase in caloric metabolism. However, ingestion of massive amounts of dinitrophenol causes toxicity by the uncoupling of oxidative phosphorylation in the mitochondria of cells. Because of this toxicity, excessive amounts can result in profuse diaphoresis, fever, thirst, tachycardia and respiratory distress which can lead to hyperpyrexia, profound weight loss, respiratory failure and death. The minimum fatal human oral dose is estimated at one to three grams (approximately 20-30 mg/kg).

In methods heretofore known to using dinitrophenol to induce weight loss, while initial daily dosages have usually been much less than the toxic amount, about 100-250 mg, as the treatment progressed the patient normally developed a tolerance for dinitrophenol and the dosage was increased to obtain the same results. This increased dosage led to an increased frequency of toxic symptoms and general disuse of dinitrophenol in inducing weight loss. "


DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT

It has been discovered that the ingestion of dinitrophenol induces hypothyroidism. Athough it is not fully understood, it is believed that the normal thyroid gland produces both thyroxine (referred to herein as T4) and 3,5,3'-triiodothyronine (referred to herein as T3). However, approximately eighty percent of the serum T3 present in the body is produced by the extrathyroidal monodeiodination of T4 to T3. When dosages of dinitrophenol are taken, hypothyroidism is induced, not by a reduction in activity of the thyroid, but by a reduction of the rate of extrathyroidal conversion of T4 to T3. While both T4 and T3 are biologically active, T3 is much more active than T4. Thus, the reduction in serum T3 concentration induced by taking dinitrophenol substantially offsets the metabolic effect of the dinitrophenol. By analogy, the reduction in serum T3 concentration is similar to that observed in fasting patients. Typically, normal serum T3 concentration ranges from about 70 to about 200 ng/dl.

It has further been discovered that deficient serum T3 concentrations resulting from administration of dinitrophenol can be restored to normal concentrations by concurrently administering a thyroid hormone preparation therewith.

The amount of dinitrophenol given should be sufficient so that the patient experiences increased body temperature. Preferably, the body temperature is elevated approximately 1.degree. F. The dose of dinitrophenol required to obtain this result varies from patient to patient, depending on factors such as, for example, weight, age, health, environmental conditions, physical activity, nutrition, and psychological state, but will normally be in the range of from about 60 to about 500 mg per day, or about 0.60 to about 5.0 mg/kg of body weight per day. Preferably, the dinitrophenol is administered in daily or alternating daily dosages, insuring that no cumulative effective results, such as excessive thermogenesis.

It is essential that the amount of dinitrophenol administered not exceed toxic doses. In a few patients, adverse reactions may occur at dosages of dinitrophenol which are not effective to elevate the body temperature, contraindications including any clinical state in which there is hypermetabolism, such as hyperthyroidism, ongoing infections, and pregnancy, and any other clinical conditions such as heart disease, chronic obstructive pulmonary disease, Addison's disease, liver disorders, or renal failure. Most are safely treated with suitable results from the aforementioned dosages.

Concurrently with the administering of the dinitrophenol, or shortly thereafter, a thyroid hormone preparation is administered to the patient. As used herein, the term thyroid hormone preparation includes any suitable preparation which restores the serum T3 concentration, including preparations containing 3,5,3'-triiodothyronine, thyroxine, derivatives thereof or combinations thereof. Preferably, the thyroid hormone preparation contains T3. Because of the varying potency of such preparations, dosages of thyroid harmone preparation are reported herein on a T3 equivalent basis.

The thyroid hormone preparation is administered in an amount sufficient to maintain the pretreatment serum T3 concentration in the patient, typically about 70-200 ng/dl in normal patients. Generally, from about 25 to about 200 mcg T3 equivalent per day, or from about 0.3 to about 2.7 mcg T3 equivalent per kilogram of body weight per day, is sufficient. Preferably, the thyroid hormone preparation is administered daily. In an especially preferred embodiment, the thyroid hormone preparation is administered orally with the dinitrophenol.

As described above, the rate of extrathyroidal conversion of T4 to T3 may vary as treatment with the dinitrophenol progresses. Thus, it may be necessary to increse or decrease the dosage of the thyroid hormone preparation accordingly.

It is preferred that in the practice of the method of this invention, the patient be closely monitored, especially in the initial stages of treatment. Recommended pretreatment and initial treatment protocol includes physical examination, electrocardiogram, and stress electrocardiogram if indicated, complete blood count, urinalysis, thyroid function studies (T3, T4 and reverse T3), serum electrolytes, HDL cholesterol, serum creatinine, blood urea nitrogen, uric acid, calcium, pulmonary function tests and liver function tests including liver enzymes, biliribin, and alkaline phosphatase.

In an especially preferred embodiment, the patient is started on initially lower dosage rates of dinitrophenol, about 250 mg every other day, and thyroid hormone preparation, about 25-50 mcg/day on a T3 equivalent basis. After 2-12 weeks of this treatment, if no adverse reactions are noted, the dosage rates may be increased to about 250 mg dinitrophenol alternated daily with about 125 mg, i.e. 250 mg on even-numbered days and 125 mg on odd-numbered days, and to about 100 mcg/day thyroid hormone preparation on a T3 equivalent basis. When the weight goal of the patient is achieved, the administration of the dinitrophenol may be discontinued, and the thyroid hormone preparation continued to maintain the patient's weight. While dietary control need not be strict, weight loss and weight maintenance are facilitated by moderate caloric intake of less than about 1800 calories per day, during and following treatment. "

=============END QUOTES============

This is an exerpt from the United States Patent Office on a study of DNP use with Thyroid hormones for weight loss,then the study lists 3 examples with very good results. Each person used DNP + Thyroid drugs for almost 1 year each.


The full report can be found here:

http://patft.uspto.gov/netacgi/nph-P...S=PN/4,673,691



Just something else to ponder.

DNP works, it does downregulate the thyroid so supplementation is advised, and there are potential side effects for certain people.

PLEASE BE CAREFUL


BTW- Heretec- you should give credit to ELITE FITNESS and their "DNP for DUMMIES" page where you copied most of your information from. Not the "Gods" as you claim. Give credit where credit is due man

[Heretic]

I did, it says "credit to the gods that wrote this". I think most of it was written by DNP Guru and Animal.
The thyroid downregulation is not permanent, in fact all of DNP's side effects stop once you stop DNP use. The only documented permanent effect is cataracts, which only occured in women and only in 1 in 100,000.
Everyone knows DNP can be lethal, but only an idiot would take 2-3 GRAMS in one day (the lethal dose). Would you take 2-3 grams of Ephedrine, Clen, or Slin? No, but those can all be deadly too.
One misconception about DNP is that it works by elevating the body's temperature, which is incorrect. The increased heat is the result of ATP not being generated, which is what is actually consuming calories. In fact, if you take your core temperature during a DNP cycle you will see that is normal, and often times a degree or so LOWER than normal. It is only when your core temperature rises above normal that there may be a problem and DNP use should be stopped immediately.
At any rate that's good info bro, but I don't see much in there that hasn't been stated before and that indicates DNP should not be used for any reason. It sounds more like the opposite, they are giving details on how to use DNP therapeutically to treat obesity.
Regards,
-H-

[ironcowboy]

Just a note on the thyroid issue. I'm not disputing that it downregulates the thyroid but my personal experience has not indicated that on me. I've done blood tests the week following 10 day DNP cycles on three ocassions and my TSH levels have been uneffected by the cycle. TSH may not be a direct measure of the thyroid levels but it's the one your body uses and is the cheapest and easiest to check so I do that test along with liver, kidney, heart functions. I believe it might be longer cycles which would lower thyroid levels.

[ironcowboy]

btw, I just finished a cycle about 8 days ago and I feel great! Strong and lean, hard. I thinking that a good way to jump start a anabolic cycle would be to proceed it with a 7-10 day DNP cycle. Give yourself a few days to recover and then start the juice. Use the anabolic rebound effect from the DNP to start you cycle lean and strong. Anybody else ever do this?

[scrappy]

Originally Posted by ironcowboy

btw, I just finished a cycle about 8 days ago and I feel great! Strong and lean, hard. I thinking that a good way to jump start a anabolic cycle would be to proceed it with a 7-10 day DNP cycle. Give yourself a few days to recover and then start the juice. Use the anabolic rebound effect from the DNP to start you cycle lean and strong. Anybody else ever do this?

This is exactly what I'm planning soon. I am going to run H's DNP for 7 days, probably only at 200mg/day throughout with all the supps and preventatives, then I'm gonna hit the juice. Iron, did you run T-3 after with the juice?
After all that I'm gonna try some lipostabil to see how that goes.

[ironcowboy]

Scrappy,

I've never used T3 while on DNP. (See my post at the end of the previous page.) If I were to do a long, low dose DNP cycle then I may supplement with T3 but the short cycles don't appear to effect it or at least it doesn't register in TSH measures. I would be afraid that taking T3 during DNP would then just delay thyroid recovery even more.

[mr_meanor]

Im staarting my first cycle of DNP tomorrow,any one interested in a Diary?

[bobbo23]

Originally Posted by mr_meanor

Im staarting my first cycle of DNP tomorrow,any one interested in a Diary?

Hell yeah man the more threads about dnp, the better.

[LightWeightBaby!]

This is slightly random, but to the 2 guys (LuvMuhRoids and C A) who asked a few months ago if I was the same LWB who posts on AR, well lol I'm not! The irony being that about a week after I registered this name on Meso, I just happened to be on AR and saw someone with the same username! Clearly we both be Ronnie Coleman fans If you see...

[clomidclown]

Originally Posted by LightWeightBaby!

This is slightly random, but to the 2 guys (LuvMuhRoids and C A) who asked a few months ago if I was the same LWB who posts on AR, well lol I'm not! The irony being that about a week after I registered this name on Meso, I just happened to be on AR and saw someone with the same username! Clearly we both be Ronnie Coleman fans If you see...

I just finished an 8 day DNP cycle, and lost 9lbs. I am very pleased!!

[tcso1506]

Originally Posted by clomidclown

I just finished an 8 day DNP cycle, and lost 9lbs. I am very pleased!!

Just a shame you didnt fall over a die , scamming mother fucker!!!!!!!!!!!!!!!!!!!

[EuroDomestic]

How long should you wait in between DNP cycles?

[adrianelli]

Originally Posted by Heretic

One week would be better than two, like I said after about 9 days it kind of loses it's kick, plus you'll be miserable and want to stop anyway. I'd then take at least a week off, maybe two, to let the water bloat drain out and allow for glycogen supercompensation (anabolic rebound). But damn, when that water comes off and you see the results it's something else.
Regards,
-H-

Dove si trova il DNP?

Il suo costo ?

E come si usa a livello corporeo?