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Old 10-28-2008, 08:12 AM
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Default Long term effects of DNP?

Does it reduce mitochondrial efficiency in producing ATP? I'm talking about off-cycle of course, as in a permanent effect.

Cardiac or respiratory damage perhaps?

Shortened lifespan because of oxidative stress?

Etc.
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Old 10-28-2008, 02:01 PM
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Default Re: Long term effects of DNP?

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Old 10-28-2008, 08:32 PM
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Default Re: Long term effects of DNP?

Quote:
Originally Posted by LiveForDaPump View Post
Does it reduce mitochondrial efficiency in producing ATP? I'm talking about off-cycle of course, as in a permanent effect.
No, it does the opposite. When you go off, efficiency returns to normal, while mitochondrial density is increased.
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Cardiac or respiratory damage perhaps?
There's no reason to think DNP would damage either. As Simkins said in his extensive research on DNP in humans, "Dinitrophenol is remarkable for its lack of significant effects on the cardiovascular system even when the basal metabolic rate is raised to high levels".
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Shortened lifespan because of oxidative stress?
No, DNP decreases oxidative stress. Studies in three different specieis have shown DNP to increase lifespan. The most recent one, in mice, concluded that DNP is a "highly effective in vivo antioxidant strategy". Other effects of DNP that might increase longevity include reduced inflammation and a slowing of telomeric senescence (aging from telomere shortening).
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Old 10-28-2008, 09:48 PM
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Default Re: Long term effects of DNP?

Thanks for posting, Conciliator.

I have two other questions, if you don't mind. First, P's new formula does not include NAC, forskolin, pantothenic acid and green tea extract. Should I be worried about that? Are they required or recommended?

Second, I think one of the compounds in his new formula is lactose. I am somewhat lactose intolerant, so do you think I'd have trouble taking P's new DNP?

Last edited by LiveForDaPump; 10-28-2008 at 09:54 PM.
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Old 10-29-2008, 03:59 AM
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Default Re: Long term effects of DNP?

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Originally Posted by LiveForDaPump View Post
Thanks for posting, Conciliator.

I have two other questions, if you don't mind. First, P's new formula does not include NAC, forskolin, pantothenic acid and green tea extract. Should I be worried about that? Are they required or recommended?
I think they were good additions, but I've mentioned in the past that I think there was potential for a reaction between the DNP and the NAC. I would like to see forskolin in the formula still, but I do think the new ingredients are better fillers for the DNP. The new ingredients are used as packing agents all the time because they work well for that purpose.
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Second, I think one of the compounds in his new formula is lactose. I am somewhat lactose intolerant, so do you think I'd have trouble taking P's new DNP?
I don't think you'd have any problems. The amout of lactose is very low. While a cup of milk has somewhere around 13g, one of his caps has 0.25g. Even if you took four capsules all at once, that would still be only 1g of lactose. Probably not enough to ever notice. Lactose is actually a pretty common filler. There's just not very much in a capsule.
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Old 10-29-2008, 11:31 AM
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Default Re: Long term effects of DNP?

I know im new to this board but ive been reading alot of the threads by conciliator and have used your words of wisdom as a guideline when i first ran dnp six weeks ago. I lost 10lbs over 2 weeks working up from 200mg for the first 5 days, to 400 mg for the remaining days. im not asking for a source directly but i was wondering if someone could pm me and let me know who p is so i could get in touch with him. my usual source is a chem supplier and they have an inspection so can only do bulk shipments and not capsules due to legislation etc. I'm not confident on capping my own dnp becuase im not sure i would get measurements correct and cant find a protecol on the net which i can place my trust in. id appreciate your input guys. have a good day

thanks guys
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Old 10-29-2008, 05:00 PM
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Default Re: Long term effects of DNP?

Yeah i'd be interested to know where one might get DNP too, is it something people generally make for themselves? I haven't seen it on any online pharmacys(maybe DNP isn't the name I should search for?). Also, i've asked around the gym and haven't come in contact with anyone who knows what it is...
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Old 10-29-2008, 05:10 PM
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Default Re: Long term effects of DNP?

It's not one of the usual products used by the masses. I can get it but only in bulk- 1kg upwards, my source is reliable but im not confident on mxing it with the corn starch etc and measuring and capping it by myself. (this post hasnt infringed any forum rules has it?)

conciliator.....

do you know any good info on how to prepare your own dnp? id be really greatful as i do have access to it, but like i said its only in bulk supply so id have to cap it myself. everything i have found is pretty vague....

thanks buddy, i'd appreciate your insight
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Old 10-29-2008, 07:31 PM
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Default Re: Long term effects of DNP?

You're not talking about ScienceLabs DNP are you? 90% assay...eck.
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Old 10-29-2008, 08:31 PM
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Default Re: Long term effects of DNP?

no geeza, havent heard of them.... is that "eck" meaning theyre crap?

i get my dnp off a supplier through a close friend of mine in a different country... wont name anyone.

anyone got any info on capping your own dnp?
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