media grade vs receptor grade IGF

[gunsbilat]

Now that IGF 1 LR3 has been aroud a while I've noticed that some people are saying media grade isn't even close to receptor grade in effect. Has anyone noticed a big diference? How do you know what you're getting is real receptor grade in the first place. I used to be able to just go to the clasified section and ask around. Now I'm afraid if I use the wrong words I'll get bitch slapped by a Mod.

[NinjaStylistic]

if I'm not mistaken, pure receptor grade costs just under $6000(thats right six grand) per 1MG....So do you reall think that many ppl have used it? I would if I was a millionare, other wise media grade seems to be working just fine.


Ninja

[rickusa2000]

thats alot of cash? maybe im getting ripped but im getting receptor grade igf-1 from argentina alot cheaper than that like 1mg for 400$ also comes with lab report and the usual inserts.

[atomicone]

I've been told over and over by GenSci that there Igtropin is pure pharmacuetical grade and it's $1300 for 500IU including insurance and shipping.

[MaxRep]

Originally Posted by atomicone

I've been told over and over by GenSci that there Igtropin is pure pharmacuetical grade and it's $1300 for 500IU including insurance and shipping.

When they say pharmaceutical grade, I believe that's their way of saying media grade. The price you mention breaks down to $260/1,000mcg... which is pretty much the going price for media grade, when you also factor in the insurance and shipping costs.

Receptor grade is generally going to cost 10x more than media grade. I don't personally know anyone who has used genuine receptor grade. The products coming out of South America and China are knock offs and from what I have seen, researched and been told, are all media grade... despite what some salesman or piece of paper says.

True receptor grade is available from the originator and patent holder, Gropep. I wouldn't get it from anyone else.

MaxRep

[atomicone]

Interesting. Is there that big of a difference between the two?

[MaxRep]

Originally Posted by atomicone

Interesting. Is there that big of a difference between the two?

My understanding is there isn't much, if any, of a difference in effects. A human user could probably never tell which one they were taking. The difference would be noticable to scientists conducting lab experiments using objective measures.

Gropep is the company which originally engineered and patented IGF-1LR3. The following is from their website. You'll notice the difference between media and receptor is in the purity, which is >85% and >95% respectively.

MaxRep
__________________________________________________ _____________
Human LONG™R³IGF-I (Media Grade)
Description:
GroPep scientists have produced Media Grade human LONG™R³IGF-I to provide an inexpensive yet high quality potent IGF-I analog for use as a growth factor supplement for serum-free or reduced-serum culture media. GroPep scientists have engineered this analog with the express purpose of increasing the biological activity of the IGF-I molecule. LONG™R³IGF-I is significantly more potent than human IGF-I in vitro. The enhanced potency is due to decreased binding of LONG™R³IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs.

LONG is a trade mark owned by GroPep Limited

LONG™R³IGF-I is covered by the following patents assigned to GroPep:
US patent 5,330,971; European patent 429,586; Japanese patent 2,682,738; Australian patent 633,099; Canadian patent 2,033,176

Purity:
> 85 % (by HPLC)
Molecular Weight:
9110 +/- 2 daltons – confirmed by Mass Spectrometry
N-terminal sequence analysis:
18 residues > 95 % single sequence


Human LONG™R³IGF-I (Receptor Grade)
Description:
Human LONG™R³ Insulin-like Growth Factor-I (IGF-I) is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R³), and a 13 amino acid extension peptide at the N-terminus. GroPep scientists have engineered this analog with the express purpose of increasing biological activity. Human LONG™R³IGF-I is significantly more potent than human IGF-I in vitro. The enhanced potency is due to the markedly decreased binding of human LONG™R³IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs.

LONG is a trade mark owned by GroPep Limited

LONG™R³IGF-I is covered by the following patents assigned to GroPep:
US patent 5,330,971; European patent 429,586; Japanese patent 2,682,738; Australian patent 633,099; Canadian patent 2,033,176;

Purity:
>95 % (by HPLC and N-terminal sequence analysis)
Molecular Weight:
9111 daltons – confirmed by Mass Spectrometry
N-terminal sequence analysis:
18 residues > 95 % single sequence

[Buckwheat]

Looks like ancillaryguys.com have receptor grade LR3IGF1 for $450 per mg.............

???

[atomicone]

Hell, I emailed GenSci again and their response this time was that their "Igtropin is the same quality as their Jintropin (whatever that means)." The stuff works and is pretty resonably priced so I'll probably stick with it. However, IGF is not hGH, it has way more side effects and is kinda scary in my opinion.