OK AAS Chemists, Question 4 U

[role model]

OK, let's say I was to run test/deca/winny...do they hit diff. receptor sites or hit receptor sites differently? If not, what would be the point in using diff. types of AAS, why not only use one compound?

I know winny is 17 alpha-methyl-5alpha- androstano
and Deca is 19-Nor-4-androstene-3-one,17b-ol
and test is 4-androstene-3-one,17beta-ol

But damed if I know if they hit receptor sites differently to work better?

Thank you.

[Beefy]

The exact mechanism of action with all steroids is not fully understood yet. All steroids are received at the receptor in the muscle tissue, however they may also trigger anabolic or androgenic actions by other means.

Winstrol and masteron are known to lower sex hormone binding globunin (SHBG) throughout your body, and therefore increase the effectiveness of all AAS you may be taking. Deca and trenbolone are very well received at the muscle receptor site, and can stay bound and active for weeks after you have discontinued usage. There is much more to learn about the positive and negative effects of AAS use. I recommend Anabolics 2006 as a great reference tool for learning the basics of AAS and how they work. I ordered a copy from Meso some time ago.

[rpmjr19]

Class I steroids are steroids that bond strongly to the receptors. These include Testosterone, Fina, EQ, Anavar, and Primobolan.

Class II steroids are steroids that promote protein synthesis by other means than bonding to the receptor sites. This means that their primary anabolic action is not from binding to the receptors (they may bond a little, but very weakly) and they promote growth by other means such as glycogen retention, etc., or even by some "unknown" means in some cases. These steroids would include D-bol, Anadrol, Winstrol, and Halotestin.

Generally, a well-rounded cycle will have Test as it's base. Then a drug from either or both Class I or II.

For instance, it would not make as much sense to make a cycle out of Test, Fina and Anavar (all Class I steroids). Not to say you wouldn't have good gains from such a cycle. But perhaps making a cycle out of Test, Fina and a little D-bol would be more "complete." You could get anabolic activity by more various means and PERHAPS have better gains.

Also, it is not wise to combine more than one 17-alpha-alkalated (17-aa) steroids at the same time. These steroids are made to withstand being destroyed by the liver on the first pass and therefore give the liver additional stress. They are made this way to increase the half-life of the steroid. So combining two of these types of steroids is not healthy on the liver. 17-aa steroids include D-bol, Anadrol, Winstrol, Anavar, and Halotestin.





thats a copied and pasted, so it reads like a newbie to understand,i know your not a newbie but I think it answers your question, atleast a little bit

[Beefy]

Good post , rpmjr19. You said what I wanted to, but couldn't.

[rpmjr19]

Originally Posted by Beefy

Good post , rpmjr19. You said what I wanted to, but couldn't.

thanks

[role model]

Originally Posted by rpmjr19

Class I steroids are steroids that bond strongly to the receptors. These include Testosterone, Fina, EQ, Anavar, and Primobolan.

Class II steroids are steroids that promote protein synthesis by other means than bonding to the receptor sites. This means that their primary anabolic action is not from binding to the receptors (they may bond a little, but very weakly) and they promote growth by other means such as glycogen retention, etc., or even by some "unknown" means in some cases. These steroids would include D-bol, Anadrol, Winstrol, and Halotestin.

Generally, a well-rounded cycle will have Test as it's base. Then a drug from either or both Class I or II.

For instance, it would not make as much sense to make a cycle out of Test, Fina and Anavar (all Class I steroids). Not to say you wouldn't have good gains from such a cycle. But perhaps making a cycle out of Test, Fina and a little D-bol would be more "complete." You could get anabolic activity by more various means and PERHAPS have better gains.

Also, it is not wise to combine more than one 17-alpha-alkalated (17-aa) steroids at the same time. These steroids are made to withstand being destroyed by the liver on the first pass and therefore give the liver additional stress. They are made this way to increase the half-life of the steroid. So combining two of these types of steroids is not healthy on the liver. 17-aa steroids include D-bol, Anadrol, Winstrol, Anavar, and Halotestin.

thats a copied and pasted, so it reads like a newbie to understand,i know your not a newbie but I think it answers your question, atleast a little bit

I found this also.

STACKING 101:

Okay, I'm going to attempt to address a piece of the puzzle towards effective combinations of compounds from a more scientific standpoint than just throwing two drugs together haphazardly so we can say we're"stacking". Keep in mind there are MANY variables here, and I'm only addressing one key (yet important) issue: Anabolic steroids work through more than one pathway-activating the androgen receptor (A/R) is only one of them. Some A/S is effective in certain pathways but not others. It's best to use a combination that covers both androgen receptors mediated activity and non-A/R mediated activity (outside of the A/R). Examples of drugs that do not bind well to the A/R and thus achieve their effectiveness through other pathways are Anadrol-50, Dianabol, and winstrol. Drugs that possess strong binding affinity to the A/R and thus achieve their effects through this mechanism are as follows: Oxandrolone, equipoise, primobolan depot, and nandrolone (deca). *Note-Testosterone exhibits powerful effects through both A/R and non-A/R pathways. This is one of the reasons that it is universally accepted as the most powerful "stand-alone" muscle builder (trenbolone also shares similar characteristics). Based on the above information, let's look at combining groups for complete growth through different pathways. Effective combinations could be (but are not limited to)--Testosterone/trenbolone + Dianabol or winstrol***Deca/equipoise + winstrol or dianabol***Primobolan/Equipoise + winstrol, d-bol or anadrol-50***Oxandrolone + winstrol or d-bol (*note-even though this would be a double AA-17 cycle, oxandrolone actually, for some odd reason exhibits very little liver toxicity, hence the 2 together should be okay). There are many different combinations that can be played with from the above selection, just be sure to include one from each group (A/R**non-A/R activity) for maximum effectiveness. Well, as stated above, this gives only a piece of the puzzle, but hopefully it will lay a little groundwork down for some of you guys, so you can start experimenting with different compounds with a direct purpose in mind.
A classic example of this type of synergy exists in the age-old deca/d-bol stack. Most users years ago probably had no idea why these two compounds worked so terrifically together, they just knew that when combined, they seemed to amplify the effects of each other. This is due to the fact that deca has a potent binding affinity to the A/R, whereas dianabol is very powerful outside of the A/R, thus each one takes up the space where the others weakness left off, making for a potent one-two punch of anabolic activity....
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[atomicone]

I would guess that like many other substances that are 'similar' or in the same drug class, Test, Deca, and Winny would attach to some of the same receptors (although at various degrees), and would also individually hit specific receptors unique to each substance. IMO, taking multiple AAS can be quite effective (especially when mixed properly). However, combining certain AAS that share to many chemical properties is usually a waste of time and money (e.g. Deca +Eq, Test Cyp +Test E, and even Winstrol + Anavar). That's my .02!

Good Luck!

Note: Very good question and I think that combining Test, Deca, and Winstrol is a pretty effective stack.