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Steroid Forum: This is a discussion on pct question within the Anabolic Steroids forums, part of the extensive steroid information at MESO-Rx; i read in a few posts that Nolvadex lowers IGF -1 by more then 15%...i know Arimidex is an alternitive ...

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Old 12-05-2009, 11:21 PM
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Default pct question

i read in a few posts that Nolvadex lowers IGF-1 by more then 15%...i know Arimidex is an alternitive but might block out all estro (which i believe is not advisable)...how about clomid?
i know its primary use is to bring back natural test production but will it also help with water retention and gyno?
im starting 1st cyc in jan...test e 250mg weekly.
Thank you all for your help!!!
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Old 12-06-2009, 03:08 AM
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Default Re: pct question

Quote:
Originally Posted by number11 View Post
i read in a few posts that Nolvadex lowers IGF-1 by more then 15%...i know Arimidex is an alternitive but might block out all estro (which i believe is not advisable)...how about clomid?
i know its primary use is to bring back natural test production but will it also help with water retention and gyno?
im starting 1st cyc in jan...test e 250mg weekly.
Thank you all for your help!!!
Some writers like Dharkam recommend avoiding Nolvadex for this and other reasons :

Quote:
Nolvadex has been shown to behave as estrogens in skeletal muscles (5). This is a very good thing for every athletes except bodybuilders. You see, estrogens protect muscle cells from the training-induced damages (5-6). It means that one can train more without damaging his muscles. Recovery will also be much faster. But for bodybuilders, the training-induced damages are a key ingredient to trigger growth. Nolvadex will therefore reduce the muscle building effects of resistance training.

As for the impact of Tamoxifen on IGF-1, it simply demonstrates another estrogen-like action of Nolvadex. By rendering the liver less sensitive to growth hormone (probably by reducing the liver density of GH receptors), estrogens and tamoxifen diminish the production of IGF-1. This action of estrogens explains why women produce less IGF-1 than men even though the have a higher GH level.

Should Nolvadex be Avoided at All Cost? by Dharkam
But not everyone's share this viewpoint:

Oxandrolon questions
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Old 12-06-2009, 01:22 PM
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Default Re: pct question

great responce, thx!
i leaning more towards clomid for both my estro blocker and part of my pct.
i know that hcg is the best but since this will be my first test cyc (250mgtest e per week) im hoping clomid would be good enough. 250 per week is real light 10 weeks (hoping to avoid hcg)
would i be correct in saying that clomid aids in bringing back natural test production as well? if so then i think i will stay with clomid only.
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Old 12-06-2009, 01:42 PM
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Default Re: pct question

Quote:
Originally Posted by number11 View Post
great responce, thx!
i leaning more towards clomid for both my estro blocker and part of my pct.
i know that hcg is the best but since this will be my first test cyc (250mgtest e per week) im hoping clomid would be good enough. 250 per week is real light 10 weeks (hoping to avoid hcg)
would i be correct in saying that clomid aids in bringing back natural test production as well? if so then i think i will stay with clomid only.
Clomid helps recovery at the pituitary level. HCG helps recovery at the testicular level.
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Old 12-06-2009, 02:13 PM
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Default Re: pct question

Quote:
Originally Posted by number11 View Post
great responce, thx!
i leaning more towards clomid for both my estro blocker and part of my pct.
i know that hcg is the best but since this will be my first test cyc (250mgtest e per week) im hoping clomid would be good enough. 250 per week is real light 10 weeks (hoping to avoid hcg)
would i be correct in saying that clomid aids in bringing back natural test production as well? if so then i think i will stay with clomid only.
In all likelihood, you do not need to do any PCT after delatestryl (testosterone enanthate 250mg/week). I can guarantee that the HPTA will return to normal naturally. Ten weeks is a very short course. I have had a few patients with problems of HPTA normalization after a short course of nandrolone.

However, if you want to do a PCT, one should strongly consider hCG. I have published and posted in details on hCG, clomiphene, and tamoxifen. If you search posts, you will find plenty of info. The only sure way to know about the HPTA - TESTING.

Millard is correct that the use of these drugs are for different purposes. In any PCT, the first objective is to return testes function. After, the goal is to return hypothalamo-pituitary function.

Do you know the differences between tamoxifen and clomiphene? Do you know the use of an aromatization inhibitor while using a testosterone ester might aid in HPTA return?
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Old 12-06-2009, 10:38 PM
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Default Re: pct question

thanks for the reply
i actually do not know the differences between tamoxifen and clomiphene but i will def look it up. thanks
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Old 12-06-2009, 11:31 PM
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Default Re: pct question

I've been using Toremifene and the boys come back very quickly.
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Old 12-07-2009, 12:42 AM
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Default Re: pct question

Quote:
Originally Posted by asih.net View Post
In all likelihood, you do not need to do any PCT after delatestryl (testosterone enanthate 250mg/week). I can guarantee that the HPTA will return to normal naturally. Ten weeks is a very short course. I have had a few patients with problems of HPTA normalization after a short course of nandrolone.

However, if you want to do a PCT, one should strongly consider hCG. I have published and posted in details on hCG, clomiphene, and tamoxifen. If you search posts, you will find plenty of info. The only sure way to know about the HPTA - TESTING.

Millard is correct that the use of these drugs are for different purposes. In any PCT, the first objective is to return testes function. After, the goal is to return hypothalamo-pituitary function.

Do you know the differences between tamoxifen and clomiphene? Do you know the use of an aromatization inhibitor while using a testosterone ester might aid in HPTA return?
tamoxifen = nolva clomiphene=clomid
i believe one actually inhibitos while the other,nolva mimics the estro receptor...?
i also believe that clomid also aids in hpta, pls correct me if im wrong.
thx
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