Tolerance to Clen?

[Zandria]

Hi I built myself a t3+clen cycle.

Bought tabs from a .com and started my cycle. I was doing clen 20mg, 40mg, 60mg, one week on, one week off. During the first week i uped the dose to 40mg, and the second clen on week i did 40mg-60mg. After one month i tapered down and ended the cycle early. During that whole month i felt no change, never had any sides, and following the same diet and exercise routine i notticed NO change.

I decided it was my source, i got riped off. I bought 4 bottles of t3, and 6 of clen from ag-guys.com, ive heard their products were good, and with their rep they would not pass of fakes. I built another t3 and clen cycle. The t3 ammounts were the same, but i started with 40mg of clen, after a few days went to 65mg, then the next clen on week was doing 60mg-80mg. Then i taped down and stoped, i didnt want to over dose.... strange though again i felt no sides and no effects. I know the ag-guys research cem was real, so why is it not effecting me?

I am female, whats the max dose i can experiment with? And why would Clen not effect me?

[Zandria]

please, anyone... i know alot of you have taken clen before and i cant be the only one to not feel effects

[MaxRep]

First, let's talk about these products in the correct dosages. When talking about T4, T3 or clen, we're talking about microgram (mcg) dosages.

Second, there are no black and white dosage numbers. You simply take an amount of clen which should work, and adjust it based on exactly how it works for you. I advise most people to go up to 100mcg/day and adjust up or down from there. I've got a very large friend who doesn't seem to get much benefit or heart rate increast/temperature increase at anything less than 200mcg's/day.

As far as overdosing, you'll know it when it happens. If you go up in roughly 25mcg increments, you won't ever overdose to the point of harm. You may feel slightly uncomfortable... big deal... and you just back down a little.

On Clen, you should be able to go about 2 weeks before needing to stop due to receptor down-regulation.

T3 amounts should probably be roughly half your clen amounts. T3 however can be run for several months before you start to suppress your natural thyroid production.

Good luck,
MaxRep

P.S. to explain what I mean by "go up to 100mcg/day" ... you start at 25mcg for a few days, then go to 50mcg/day for a few days, then 75mcg/day for a few days, and at any time you may be at the right dosage for you. However, you'll probably not stop until 75mcg/day or for most people 100mcg/day. Then at 100, you may feel that's too much, and need to back down... or it will be necessary to keep going up until you hit that point where you're taking a little too much, and then you back down and in the future, you'll know the right amount for you.

[rpmjr19]

MaxRep, whe you said "T3 however can be run for several months before you start to suppress your natural thyroid production." I have read otherwise from some other sites, I was under the impression you can suppress your natural thyroid production much faster than a couple months, like within 6 weeks.

Is that information wrong that I have found?

[MaxRep]

In terms of what amount of t4 causes suppression, there's a fairly wide range in the area of 100mcg - 300mcg/day. The amount of T3 that will after time cause suppression would be approximately 25mcg-75mcg/day. In terms of what time frame does it take for suppression to occur, that's hard to say but could be as long as 6 months. It changes with several variables but to be safe, I personally don't take daily t4/t3 for more than one-two months at a time.

J Clin Endocrinol Metab. 1978 Jul;47(1):78-83.
"...The mean T4 dose that nearly obliterated the TSH response was 200 micrograms; this degree of suppression occurred with doses of 100-300 micrograms T4 in individual patients. Suppression of thyroid uptake correlated closely with suppression of the TSH response to TRH..."

J Clin Endocrinol Metab. 1987 Apr;64(4):849-55.
"... The duration of treatment also proved to be an important parameter, since in both groups the percentage of patients with suppressed TSH secretion increased if TRH testing was carried out after at least 6 months after the initiation of therapy...
...In conclusion: TSH suppression requires daily doses of T4 between 2.5 and 2.9 micrograms/kg BW in athyreotic patients and between 1.9 and 2.3 micrograms/kg BW in goitrous patients, with appropriate adjustments in relation to the age of the patient;..."

Note that when talking about thyroid suppression, we're really talking about suppression of Thyroid Stimulating Hormone, as it's the suppression of this hormone which then causes the thyroid to Not produce any t4/t3.

Best regards,
MaxRep

[van-man]

more eye opening advice from everybodies favorite mod...MaxRep!

Now I wonder how much T3 and T4 is produced per uIU/ml of TSH?
I suppose that varies per individual too though...

[MaxRep]

Originally Posted by van-man

Now I wonder how much T3 and T4 is produced per uIU/ml of TSH?
...

Uhhhh... I'll let you research that one Van...

Best regards,
MaxRep

[van-man]

Originally Posted by MaxRep

Uhhhh... I'll let you research that one Van...

Best regards,
MaxRep

I wouldn't even know where to begin...
and if I ask my doc, he'll just give me shit like he always does... "Van, do you try to make things more complicated or is this just something that comes natural to you?"

[MaxRep]

Originally Posted by van-man

if I ask my doc, he'll just give me shit like he always does... "Van, do you try to make things more complicated or is this just something that comes natural to you?"

Well... I see I'm not the only one that feels that way...

Oh Yeah! I almost forgot... I kind of already know the answer to part of your question. T4 is actually the hormone primarily produced by thyroid gland. Very little T3 is actually produced, somewhere around 10-15%% of the amount of T4 produced, as the body converts the produced T4 into T3. The amount of T4 produced daily is in the area of 100-150mcg's, plus about 10-20mcg's of T3.

Best regards,
MaxRep

[van-man]

hmm... I knew that there was conversion that happened between the T4 and T3, but I didn't know how much.

I'm a little bit intimidated by T3 due to the power of that hormone so I want to really have a good grasp of how its going to be working before I go introducing it into any cycles. And to be honest I'm not too sure I couldn't get away with something easier.

[bastiaan0740]

Clen is a weird compound forsure. I've seen guys not able to tolerate 100mµg, and others taking 200mµg without any positive effect or side-effect. And I'm talking about tabs from the same bottle.

[Zandria]

Thank you for the help. So just to clairify before i start my next cycle. because i have used ag-gys t3+clen and at 80mcg at the max, i should start at 75mcg then every 3 days increase it by 25 if i feel no effects? How would i be able to guage if my T3 is effecting me? or should i just keep that at what it was before?

And just saying this again because its kinda important, i am a woman! (one time asking about var and primo some guy was telling me to take test e and sust - so now i try to make my gender known).

As far as tolerance goes, when i run my first var cycle in the spring should i consider running into a tolerance problem? I was planing to take 5mg-15mg in an 11 week cycle.

[van-man]

With any AAS cycle man or woman I've always believed that one should just just what is necessary to provide adequate gains and nothing more. If your are seeing satisfactory results with 5 or 10mg, then there is no need to push it up IMO.

[jboldman]

and of course do not forget the damage to your heart at relatively how doses from clen.

jb